Arina Tamborska
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View article: OpenPrescribing Hospitals: An open access analytics platform for hospital medicines use in England
OpenPrescribing Hospitals: An open access analytics platform for hospital medicines use in England Open
Primary care prescribing data for general practices in England has been openly published since 2011. The OpenPrescribing platform provides an open, transparent and easy-to-use interface to this data. OpenPrescribing is widely used by NHS p…
View article: <i>OpenCodeCounts</i>: An open-access, interactive online tool and R package for analysing clinical code usage in England
<i>OpenCodeCounts</i>: An open-access, interactive online tool and R package for analysing clinical code usage in England Open
Clinical codes are unique identifiers used in electronic health records to document specific information, such as diagnoses, procedures or medications. Because of their structured and systematic nature, they are often used for research, au…
View article: Assessing the global variation in patient characteristics, management and short-term outcomes of spontaneous intracranial haemorrhage worldwide: a protocol for a global observational prospective multicentre study (the PLOT-ICH study)
Assessing the global variation in patient characteristics, management and short-term outcomes of spontaneous intracranial haemorrhage worldwide: a protocol for a global observational prospective multicentre study (the PLOT-ICH study) Open
Introduction Stroke is the second leading cause of death worldwide, with the greatest burden in low- and middle-income countries (LMICs). Haemorrhagic stroke or spontaneous intracranial haemorrhage (sICH), including intraparenchymal haemor…
View article: The coding of migration status in English General Practice data from 2011 to 2024
The coding of migration status in English General Practice data from 2011 to 2024 Open
ObjectivesMigration status is a determinant of health, but it is not routinely recorded in General Practice (GP) records. We explored the recording of migration-related SNOMED-CT codes (a structured clinical vocabulary used in GP records) …
View article: The relationship between general practice characteristics, case-mix, and secondary care attendances/admissions before and after the COVID-19 pandemic: Protocol for an OpenSAFELY cohort study
The relationship between general practice characteristics, case-mix, and secondary care attendances/admissions before and after the COVID-19 pandemic: Protocol for an OpenSAFELY cohort study Open
Background Healthcare services in England experience increased pressure during winter months due to seasonal infectious diseases, increased multimorbidity, and fluctuating demand. Understanding how characteristics of general practices, and…
View article: The coding of migration status in English primary care from 2011 to 2024: a pilot use of Open Code Counts
The coding of migration status in English primary care from 2011 to 2024: a pilot use of Open Code Counts Open
Background The migration status of the 9.8 million migrants living in England is not systematically recorded in primary care electronic health records (EHRs). Codelist approaches enable us to create cohorts of individuals who have had a pr…
View article: Utilising accessible and reproducible neurological assessments in clinical studies: Insights from use of the Neurological Impairment Scale in the multi-centre COVID-CNS study
Utilising accessible and reproducible neurological assessments in clinical studies: Insights from use of the Neurological Impairment Scale in the multi-centre COVID-CNS study Open
Reproducible and standardised neurological assessment scales are important in quantifying research outcomes. These scales are often performed by non-neurologists and/or non-clinicians and must be robust, quantifiable, reproducible and comp…
View article: A clinical approach to the investigation and management of long COVID associated neuropathic pain
A clinical approach to the investigation and management of long COVID associated neuropathic pain Open
COVID–19 has been associated with a wide range of ongoing symptoms following recovery from the acute SARS-CoV-2 infection. Around one in three people with COVID-19 develop neurological symptoms with many reporting neuropathic pain and asso…
View article: Corrigendum to “Global uncertainty in the diagnosis of neurological complications of SARS-CoV-2 infection by both neurologists and non-neurologists: An international inter-observer variability study” [Journal of the Neurological Sciences. 2023 Jun 15;449:120646]
Corrigendum to “Global uncertainty in the diagnosis of neurological complications of SARS-CoV-2 infection by both neurologists and non-neurologists: An international inter-observer variability study” [Journal of the Neurological Sciences. 2023 Jun 15;449:120646] Open
View article: Global uncertainty in the diagnosis of neurological complications of SARS-CoV-2 infection by both neurologists and non-neurologists: An international inter-observer variability study
Global uncertainty in the diagnosis of neurological complications of SARS-CoV-2 infection by both neurologists and non-neurologists: An international inter-observer variability study Open
View article: Anosmia: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data
Anosmia: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data Open
This is a Brighton Collaboration case definition of anosmia to be used in the evaluation of adverse events following immunization, and for epidemiologic studies for the assessment of background incidence or hypothesis testing. The case def…
View article: Anosmia: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data (Manuscript draft)
Anosmia: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data (Manuscript draft) Open
This is a Brighton Collaboration case definition of anosmia to be used in the evaluation of adverse events following immunization, and for epidemiologic studies for the assessment of background incidence or hypothesis testing. The case def…
View article: Anosmia: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data
Anosmia: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunization safety data Open
This is a Brighton Collaboration case definition of anosmia to be used in the evaluation of adverse events following immunization, and for epidemiologic studies for the assessment of background incidence or hypothesis testing. The case def…
View article: Guillain-Barré syndrome following SARS-CoV-2 vaccination in the UK: a prospective surveillance study
Guillain-Barré syndrome following SARS-CoV-2 vaccination in the UK: a prospective surveillance study Open
Objective To investigate features of Guillain-Barré syndrome (GBS) following SARS-CoV-2 vaccines and evaluate for a causal link between the two. Methods We captured cases of GBS after SARS-CoV-2 vaccination through a national, open-access,…
View article: Safety of COVID-19 vaccination and acute neurological events: A self-controlled case series in England using the OpenSAFELY platform
Safety of COVID-19 vaccination and acute neurological events: A self-controlled case series in England using the OpenSAFELY platform Open
View article: Prognostic indicators and outcomes of hospitalised COVID-19 patients with neurological disease: An individual patient data meta-analysis
Prognostic indicators and outcomes of hospitalised COVID-19 patients with neurological disease: An individual patient data meta-analysis Open
Background Neurological COVID-19 disease has been reported widely, but published studies often lack information on neurological outcomes and prognostic risk factors. We aimed to describe the spectrum of neurological disease in hospitalised…
View article: Timing of headache after COVID-19 vaccines and its association with cerebrovascular events: An analysis of 41,700 VAERS reports
Timing of headache after COVID-19 vaccines and its association with cerebrovascular events: An analysis of 41,700 VAERS reports Open
Background Delayed-onset of headache seems a specific feature of cerebrovascular events after COVID-19 vaccines. Methods All consecutive events reported to the United States Vaccine Adverse Reporting System following COVID-19 vaccines (1 J…
View article: COVID-19 vaccine associated demyelination & its association with MOG antibody
COVID-19 vaccine associated demyelination & its association with MOG antibody Open
View article: Neurological Events Reported after COVID‐19 Vaccines: An Analysis of Vaccine Adverse Event Reporting System
Neurological Events Reported after COVID‐19 Vaccines: An Analysis of Vaccine Adverse Event Reporting System Open
Objective To identify the rates of neurological events following administration of mRNA (Pfizer, Moderna) or adenovirus vector (Janssen) vaccines in the U.S. Methods We used publicly available data from the U.S. Vaccine Adverse Event Repor…
View article: Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study
Cerebral venous thrombosis after vaccination against COVID-19 in the UK: a multicentre cohort study Open
View article: Considerations for causality assessment of neurological and neuropsychiatric complications of SARS-CoV-2 vaccines: from cerebral venous sinus thrombosis to functional neurological disorder
Considerations for causality assessment of neurological and neuropsychiatric complications of SARS-CoV-2 vaccines: from cerebral venous sinus thrombosis to functional neurological disorder Open
The scientific community rapidly responded to the COVID-19 pandemic by developing novel SARS-CoV-2 vaccines (table 1). As of early June 2021, an estimated 2 billion doses have been administered worldwide.1 Neurological adverse events follo…
View article: Clinical review of cerebral venous thrombosis in the context of COVID-19 vaccinations: Evaluation, management, and scientific questions
Clinical review of cerebral venous thrombosis in the context of COVID-19 vaccinations: Evaluation, management, and scientific questions Open
View article: Defining Causality in Neurological &amp; Neuropsychiatric COVID-19 Vaccine Complications: What Have We Learnt from Current and Previous Vaccination Campaigns?
Defining Causality in Neurological & Neuropsychiatric COVID-19 Vaccine Complications: What Have We Learnt from Current and Previous Vaccination Campaigns? Open
View article: Diagnosis and management of adult patients with COVID-19 encephalopathy; consensus guidance from the Global COVID-19 Neuro Research Coalition
Diagnosis and management of adult patients with COVID-19 encephalopathy; consensus guidance from the Global COVID-19 Neuro Research Coalition Open
View article: Clinical Review of Cerebral Venous Thrombosis in the Context of COVID-19 Vaccinations: Evaluation, Management, and Scientific Questions
Clinical Review of Cerebral Venous Thrombosis in the Context of COVID-19 Vaccinations: Evaluation, Management, and Scientific Questions Open
View article: Non-invasive measurement of fasciculation frequency demonstrates diagnostic accuracy in amyotrophic lateral sclerosis
Non-invasive measurement of fasciculation frequency demonstrates diagnostic accuracy in amyotrophic lateral sclerosis Open
Delayed diagnosis of amyotrophic lateral sclerosis prevents early entry into clinical trials at a time when neuroprotective therapies would be most effective. Fasciculations are an early hallmark of amyotrophic lateral sclerosis, preceding…
View article: Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD
Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD Open
Background Due to common evolutionary origins, mitochondrial DNA (mtDNA) shares many similarities with immunogenic bacterial DNA. MtDNA is recognized as a pro-inflammatory damage-associated molecular pattern (DAMP) with a pathogenic role i…
View article: Characteristics of Randomized Trials Focusing on Stroke due to Intracerebral Hemorrhage
Characteristics of Randomized Trials Focusing on Stroke due to Intracerebral Hemorrhage Open
Background and Purpose— The absence of treatments for intracerebral hemorrhage with significant consistent benefit in randomized controlled trials (RCTs) could be because of lack of treatment efficacy or the design of RCTs. Methods— We sea…
View article: Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases
Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases Open
Mitochondrial DNA (mtDNA) has many similarities with bacterial DNA because of their shared common ancestry. Increasing evidence demonstrates mtDNA to be a potent danger signal that is recognised by the innate immune system and can directly…