Arjan Narbad
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View article: Human gut strains of <i>Desulfovibrio piger</i> exhibit spontaneous induction of multiple prophages
Human gut strains of <i>Desulfovibrio piger</i> exhibit spontaneous induction of multiple prophages Open
Sulfate-reducing bacterium Desulfovibrio piger is a common member of the human gastrointestinal microbiome, associated with inflammatory conditions but also prevalent in healthy individuals. This suggests that lifestyle factors may shape i…
View article: Draft genome sequences of <i>Limosilactobacillus fermentum</i> IJAL 01 335, isolated from a traditional cereal fermented dough
Draft genome sequences of <i>Limosilactobacillus fermentum</i> IJAL 01 335, isolated from a traditional cereal fermented dough Open
Limosilactobacillus fermentum IJAL 01 335 was isolated from mawè , a spontaneously fermented cereal dough from Benin. The 1.83 Mb draft genome sequence (52.37% GC) comprises 154 contigs, 1,836 coding sequences, and 23 predicted antibiotic …
View article: Draft genome sequence of a kombucha isolate of <i>Pichia kudriavzevii</i>
Draft genome sequence of a kombucha isolate of <i>Pichia kudriavzevii</i> Open
Pichia kudriavzevii (syn. Candida krusei ) is a fermentative yeast of importance to both the food and biotechnology industries, as well as being of significant clinical concern. Here, we report the draft genome sequence of P. kudriavzevii …
View article: Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson’s disease
Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson’s disease Open
There is strong interest in using the gut microbiome for Parkinson’s disease (PD) diagnosis and treatment. However, a consensus on PD-associated microbiome features and a multi-study assessment of their diagnostic value is lacking. Here, w…
View article: Characterization and immune-modulatory roles of branched glucan and acetylated gluco-oligosaccharides produced by glucansucrase 40 from Leuconostoc mesenteroides YTU 40
Characterization and immune-modulatory roles of branched glucan and acetylated gluco-oligosaccharides produced by glucansucrase 40 from Leuconostoc mesenteroides YTU 40 Open
Glucansucrases (GS) are functional enzymes for the production of distinct glucan and gluco-oligosaccharide structures with potential bioactive characteristics. In this study, an active glucansucrase (GS40) was identified within the genome …
View article: Temporal dynamics of SARS-CoV-2 shedding in feces and saliva: a longitudinal study in Norfolk, United Kingdom during the 2021–2022 COVID-19 waves
Temporal dynamics of SARS-CoV-2 shedding in feces and saliva: a longitudinal study in Norfolk, United Kingdom during the 2021–2022 COVID-19 waves Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was originally described as a respiratory illness; however, it is now known that the infection can spread to the gastrointestinal tract, leading to shedding in feces potentially …
View article: Genome sequence of <i>Eubacterium callanderi</i> AM6, isolated from a Parkinson’s disease patient
Genome sequence of <i>Eubacterium callanderi</i> AM6, isolated from a Parkinson’s disease patient Open
Here, we report the genome sequence of Eubacterium callanderi AM6, isolated from a fecal sample obtained from a Parkinson’s disease patient. The bacterial genome was sequenced using Illumina technology on a NextSeq 500 platform. The assemb…
View article: The nisin O cluster: species dissemination, candidate leader peptide proteases and the role of regulatory systems
The nisin O cluster: species dissemination, candidate leader peptide proteases and the role of regulatory systems Open
Nisin O is an antimicrobial peptide encoded by the human gut bacterium Blautia obeum A2-162 which has antimicrobial activity against clinically relevant organisms. The nisin O biosynthetic gene cluster (BGC) varies from other nisin BGCs as…
View article: <i>Bacteroides thetaiotaomicron</i> enhances H <sub>2</sub> S production in <i>Bilophila wadsworthia</i>
<i>Bacteroides thetaiotaomicron</i> enhances H <sub>2</sub> S production in <i>Bilophila wadsworthia</i> Open
Sulfate- and sulfite-reducing bacteria (SRB) are a group of strict anaerobes found within the human gut. Bilophila wadsworthia, a sulfite-reducing bacterium which produces hydrogen sulfide (H2S) from taurine and isethionate respiration, is…
View article: Bacteroides thetaiotaomicron enhances H<sub>2</sub>S production in Bilophila wadsworthia
Bacteroides thetaiotaomicron enhances H<sub>2</sub>S production in Bilophila wadsworthia Open
Sulfate- and sulfite-reducing bacteria (SRB) are a group of strict anaerobes found within the human gut. Bilophila wadsworthia , a sulfite-reducing bacterium which produces hydrogen sulfide (H 2 S) from taurine and isethionate respiration …
View article: Energy generation drives gut colonization by Bilophila wadsworthia
Energy generation drives gut colonization by Bilophila wadsworthia Open
High-fat diets alter the gut microbiota composition and stimulate proliferation of the sulfidogenic bacterium Bilophila wadsworthia (Bw). Proliferation of B. wadsworthia is linked to gut inflammation, dysfunction of the intestinal barrier …
View article: Characterization of a Ligilactobacillus salivarius Strain Isolated from a Cheese Seal Which Was Last Used in 1936
Characterization of a Ligilactobacillus salivarius Strain Isolated from a Cheese Seal Which Was Last Used in 1936 Open
Cheesemaking played a pivotal role in the life of the Pyrenean villages where cheese was a most prized commodity and the subject of much local competition. In one of them (Sasa de Sobrepuerto), Mrs. Sebastiana Palacio decided in 1877 to la…
View article: Cross-feeding of bifidobacteria promotes intestinal homeostasis: a lifelong perspective on the host health
Cross-feeding of bifidobacteria promotes intestinal homeostasis: a lifelong perspective on the host health Open
Throughout the life span of a host, bifidobacteria have shown superior colonization and glycan abilities. Complex glycans, such as human milk oligosaccharides and plant glycans, that reach the colon are directly internalized by the transpo…
View article: <i>Prevotella copri</i>—a potential next‐generation probiotic
<i>Prevotella copri</i>—a potential next‐generation probiotic Open
Prevotella copri , which is divided into four clades, exerts bidirectional effects on host health. These effects include positive improvements in the allergy response and insulin sensitivity. However, P. copri sometimes has adverse effects…
View article: Refined diet consumption increases neuroinflammatory signalling through bile acid dysmetabolism
Refined diet consumption increases neuroinflammatory signalling through bile acid dysmetabolism Open
Over recent decades, dietary patterns have changed significantly due to the increasing availability of convenient, ultra-processed refined foods. Refined foods are commonly depleted of key bioactive compounds, which have been associated wi…
View article: Beneficial effects of GABA-producing potential probiotic Limosilactobacillus fermentum L18 of human origin on intestinal permeability and human gut microbiota
Beneficial effects of GABA-producing potential probiotic Limosilactobacillus fermentum L18 of human origin on intestinal permeability and human gut microbiota Open
Background Gamma-aminobutyric acid (GABA) is a non-protein amino acid with neuroinhibitory, antidiabetic, and antihypertensive properties and is used as a drug for treating anxiety and depression. Some strains of lactobacilli are known to …
View article: Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson’s disease
Machine learning-based meta-analysis reveals gut microbiome alterations associated with Parkinson’s disease Open
There is strong interest in exploring the potential of the gut microbiome for Parkinson’s disease (PD) diagnosis and treatment. However, a consensus on the microbiome features associated with PD and a multi-study assessment of their diagno…
View article: Identification, activity and delivery of new LysFA67 endolysin to target cheese spoilage Clostridium tyrobutyricum
Identification, activity and delivery of new LysFA67 endolysin to target cheese spoilage Clostridium tyrobutyricum Open
Bacteriophages and their endolysins are potential biocontrol agents for the anaerobic spoilage organism Clostridium tyrobutyricum, which causes cheese late blowing defect. This study sequenced and compared the genomes of eight bacteriophag…
View article: Intraspecific difference of <i>Latilactobacillus sakei</i> in inflammatory bowel diseases: Insights into potential mechanisms through comparative genomics and metabolomics analyses
Intraspecific difference of <i>Latilactobacillus sakei</i> in inflammatory bowel diseases: Insights into potential mechanisms through comparative genomics and metabolomics analyses Open
Inflammatory bowel diseases (IBDs) are chronic inflammatory diseases of the gastrointestinal tract that have become a global health burden. Studies have revealed that Latilactobacillus sakei can effectively alleviate various immune disease…
View article: Spontaneous and Microbiota‐Driven Degradation of Anthocyanins in an In Vitro Human Colon Model
Spontaneous and Microbiota‐Driven Degradation of Anthocyanins in an In Vitro Human Colon Model Open
Scope The consumption of dietary anthocyanins is associated with various health benefits. However, anthocyanins are poorly bioavailable, and most ingested anthocyanins will enter the colon where they are degraded to small phenolic metaboli…
View article: Unravelling phenolic metabotypes in the frame of the COMBAT study, a randomized, controlled trial with cranberry supplementation
Unravelling phenolic metabotypes in the frame of the COMBAT study, a randomized, controlled trial with cranberry supplementation Open
Cranberry (poly)phenols may have potential health benefits. Circulating (poly)phenol metabolites can act as mediators of these effects, but they are subjected to an extensive inter-individual variability. This study aimed to quantify both …
View article: In Vitro Fermentation of Hyaluronan with Different Molecular Weights by Human Gut Microbiota: Differential Effects on Gut Microbiota Structure and Metabolic Function
In Vitro Fermentation of Hyaluronan with Different Molecular Weights by Human Gut Microbiota: Differential Effects on Gut Microbiota Structure and Metabolic Function Open
Hyaluronan (HA) has various biological functions and is used extensively as a dietary supplement. Previous studies have shown that the probiotic effects of polysaccharides are closely associated with their molecular properties. The intesti…
View article: Cholestasis: exploring the triangular relationship of gut microbiota-bile acid-cholestasis and the potential probiotic strategies
Cholestasis: exploring the triangular relationship of gut microbiota-bile acid-cholestasis and the potential probiotic strategies Open
Cholestasis is a condition characterized by the abnormal production or excretion of bile, and it can be induced by a variety of causes, the factors of which are extremely complex. Although great progress has been made in understanding chol…
View article: Advances in Lactobacillus Restoration for β-Lactam Antibiotic-Induced Dysbiosis: A System Review in Intestinal Microbiota and Immune Homeostasis
Advances in Lactobacillus Restoration for β-Lactam Antibiotic-Induced Dysbiosis: A System Review in Intestinal Microbiota and Immune Homeostasis Open
A balanced gut microbiota and their metabolites are necessary for the maintenance of the host’s health. The antibiotic-induced dysbiosis can cause the disturbance of the microbial community, influence the immune homeostasis and induce susc…