Amit K. Mathur
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View article: Updates on the impact of the new liver allocation policy on national liver transplants
Updates on the impact of the new liver allocation policy on national liver transplants Open
View article: Survey of Early Practices and Perceptions of Liver Machine Perfusion Among US Liver Transplant Surgeons
Survey of Early Practices and Perceptions of Liver Machine Perfusion Among US Liver Transplant Surgeons Open
Background. Ex vivo machine perfusion (MP) has transformed organ preservation, offering significant benefits in liver transplantation (LT), particularly with high-risk donor grafts. However, adoption in the United States has been limited. …
View article: Donation After Circulatory Death Liver Transplantation: Impact of Normothermic Machine Perfusion on Key Variables
Donation After Circulatory Death Liver Transplantation: Impact of Normothermic Machine Perfusion on Key Variables Open
BACKGROUND: During orthotopic liver transplantation, allograft reperfusion is a dynamic point in the operation and often requires vasoactive medications and blood transfusions. Normothermic machine perfusion (NMP) of liver allografts has e…
View article: Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Neuroprotection strategies in the neonate
Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Neuroprotection strategies in the neonate Open
BACKGROUND: Cerebral intraventricular hemorrhage (IVH) is a major cause of neurodevelopmental impairment in preterm infants.IVH is characterized by vessel rupture and a rapid accumulation of blood within the ventricles.Subsequent hemolysis…
View article: Commentary: DCD liver transplant in patients with a MELD over 35
Commentary: DCD liver transplant in patients with a MELD over 35 Open
This article is a commentary on: DCD liver transplant in patients with a MELD over 35 Read original article
View article: The Dallas Donation after Circulatory Death Transplantation Summit: expanding donation after circulatory death procedures through process improvement, broader utilization, and innovation
The Dallas Donation after Circulatory Death Transplantation Summit: expanding donation after circulatory death procedures through process improvement, broader utilization, and innovation Open
Despite a significant increase in utilization over the past decade, the number of donation after circulatory death (DCD) organs that are procured and transplanted in the United States (US) remains well below its potential. There is still r…
View article: Pragmatic strategies to address health disparities along the continuum of care in chronic liver disease
Pragmatic strategies to address health disparities along the continuum of care in chronic liver disease Open
Racial, ethnic, and socioeconomic disparities exist in the prevalence and natural history of chronic liver disease, access to care, and clinical outcomes. Solutions to improve health equity range widely, from digital health tools to policy…
View article: Table of Contents
Table of Contents Open
View article: Autophagy: a necessary evil in cancer and inflammation
Autophagy: a necessary evil in cancer and inflammation Open
View article: Breaking Barriers and Bridging Gaps: Advancing Diversity, Equity, and Inclusion in Kidney Transplant Care for Black and Hispanic Patients in the United States
Breaking Barriers and Bridging Gaps: Advancing Diversity, Equity, and Inclusion in Kidney Transplant Care for Black and Hispanic Patients in the United States Open
Kidney transplantation offers better mortality and quality of life outcomes to patients with end-stage renal failure compared to dialysis. Specifically, living donor kidney transplantation is the best treatment for end-stage renal disease,…
View article: Safety attitudes culture remain stable in a transplant center: evidence from the coronavirus pandemic
Safety attitudes culture remain stable in a transplant center: evidence from the coronavirus pandemic Open
Background We sought to understand how safety culture may evolve during disruption, by using the COVID-19 pandemic as an example, to identify vulnerabilities in the system that could impact patient outcomes. Methods A cross-sectional analy…
View article: Early patient and liver allograft outcomes from donation after circulatory death donors using thoracoabdominal normothermic regional: a multi-center observational experience
Early patient and liver allograft outcomes from donation after circulatory death donors using thoracoabdominal normothermic regional: a multi-center observational experience Open
Background Donation after circulatory death (DCD) liver allografts are associated with higher rates of primary non-function (PNF) and ischemic cholangiopathy (IC). Advanced recovery techniques, including thoracoabdominal normothermic regio…
View article: Spontaneous middle lobe torsion: An institutional case series
Spontaneous middle lobe torsion: An institutional case series Open
As the result of its rarity, radiographic and clinical diagnosis of spontaneous pulmonary lobar torsion is challenging; a high index of suspicion for spontaneous middle lobe torsion must be maintained to avoid delays in diagnosis. Prompt s…
View article: Financial, policy, and ethical barriers to the expansion of living donor liver transplant: Meeting report from a living donor liver transplant consensus conference
Financial, policy, and ethical barriers to the expansion of living donor liver transplant: Meeting report from a living donor liver transplant consensus conference Open
Introduction In October 2021, the American Society of Transplantation (AST) hosted a virtual consensus conference aimed at identifying and addressing barriers to the broader, safe expansion of living donor liver transplantation (LDLT) thro…
View article: Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis
Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis Open
The acuity circles (AC) liver distribution policy, implemented in February 2020 in the United States, was intended to address concerns over geographic variability in the median model for end-stage liver disease at transplant (MMaT) across …
View article: Cover Image, Volume 6, Issue 2
Cover Image, Volume 6, Issue 2 Open
The cover image is based on the Research Letter Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis by Emmanouil Giorgakis et al., ht…
View article: The impact of COVID-19 on kidney transplant care
The impact of COVID-19 on kidney transplant care Open
The SARS-CoV-2 virus precipitated the coronavirus 2019 (COVID-19) pandemic, which placed considerable strain on healthcare systems and necessitated immediate and rapid alterations in the delivery of healthcare. In the transplant population…
View article: Association of DGF and Early Readmissions on Outcomes Following Kidney Transplantation
Association of DGF and Early Readmissions on Outcomes Following Kidney Transplantation Open
Concerns regarding outcomes and early resource utilization are potential deterrents to broader use of kidneys at risk for delayed graft function (DGF). We assessed outcomes specific to kidneys with DGF that required early readmission follo…
View article: Financial Impact of a Culturally Sensitive Hispanic Kidney Transplant Program on Increasing Living Donation
Financial Impact of a Culturally Sensitive Hispanic Kidney Transplant Program on Increasing Living Donation Open
Background. In the United States, Hispanic/Latinx patients receive disproportionately fewer living donor kidney transplants (LDKTs) than non-Hispanic White patients. Northwestern Medicine’s culturally targeted Hispanic Kidney Transplant Pr…
View article: Outcomes of endoscopic retrograde cholangiography and percutaneous transhepatic biliary drainage in liver transplant recipients with a Roux-en-Y biliary-enteric anastomosis
Outcomes of endoscopic retrograde cholangiography and percutaneous transhepatic biliary drainage in liver transplant recipients with a Roux-en-Y biliary-enteric anastomosis Open
In LT patients with Roux-BE anastomosis requiring biliary intervention, ERC with a balloon-assisted enteroscope is safe with a success rate comparable to PTBD. Both ERC and PTBD can be considered as first-line therapies for LT recipients w…
View article: Hepatocellular Carcinoma, Alpha Fetoprotein, and Liver Allocation for Transplantation: Past, Present and Future
Hepatocellular Carcinoma, Alpha Fetoprotein, and Liver Allocation for Transplantation: Past, Present and Future Open
Hepatocellular carcinoma (HCC) is one of the leading indications for liver transplantation and has been the treatment of choice due to the oncologic benefit for patients with advanced chronic liver disease (AdvCLD) and small tumors for the…
View article: DCD Liver Grafts Can Safely Be Used for Recipients With Grade I–II Portal Vein Thrombosis: A Multicenter Analysis
DCD Liver Grafts Can Safely Be Used for Recipients With Grade I–II Portal Vein Thrombosis: A Multicenter Analysis Open
Background. With donation after circulatory death (DCD) liver transplantation (LT), the goal of the recipient implantation procedure is to minimize surgical complexity to avoid a tenuous environment for an already marginal graft. The prese…
View article: Risk factors associated with urgent surgical reintervention due to postoperative hemorrhage after orthotopic liver transplantation
Risk factors associated with urgent surgical reintervention due to postoperative hemorrhage after orthotopic liver transplantation Open
Studies reporting risk factors associated with reoperation due to hemorrhage after orthotopic liver transplantation (OLT) have presented conflicting results and several limitations. In a large contemporary cohort of OLT, we sought to ident…
View article: Decreasing Significance of Early Allograft Dysfunction with Rising Use of Nonconventional Donors
Decreasing Significance of Early Allograft Dysfunction with Rising Use of Nonconventional Donors Open
Background and Objectives: Early allograft dysfunction (EAD) is considered a surrogate marker for adverse post-liver transplant (LT) outcomes. With the increasing use of nonconventional donors, EAD has become a more frequent occurrence. Gi…
View article: Disparities in the Use of Older Donation After Circulatory Death Liver Allografts in the United States Versus the United Kingdom
Disparities in the Use of Older Donation After Circulatory Death Liver Allografts in the United States Versus the United Kingdom Open
Background. This study aimed to assess the differences between the United States and the United Kingdom in the characteristics and posttransplant survival of patients who received donation after circulatory death (DCD) liver allografts fro…
View article: Immune Checkpoint Inhibitors as Therapy to Down-Stage Hepatocellular Carcinoma Prior to Liver Transplantation
Immune Checkpoint Inhibitors as Therapy to Down-Stage Hepatocellular Carcinoma Prior to Liver Transplantation Open
Hepatocellular Carcinoma (HCC) is the most common liver malignancy and third leading cause of cancer death worldwide. For early- and intermediate-stage disease, liver-directed therapies for locoregional control, or down-staging prior to de…
View article: Donation after circulatory death transplant outcomes using livers recovered by local surgeons
Donation after circulatory death transplant outcomes using livers recovered by local surgeons Open
Donation after circulatory death (DCD) liver transplantation (LT) outcomes have been attributed to multiple variables, including procurement surgeon recovery techniques. Outcomes of 196 DCD LTs at Mayo Clinic Arizona were analyzed based on…
View article: Clinical outcomes for hilar and extrahepatic cholangiocarcinoma with adjuvant, definitive, or liver transplant-based neoadjuvant chemoradiotherapy strategies: a single-center experience
Clinical outcomes for hilar and extrahepatic cholangiocarcinoma with adjuvant, definitive, or liver transplant-based neoadjuvant chemoradiotherapy strategies: a single-center experience Open
Outcomes for patients with extrahepatic CCA were superior for those who underwent nCRT/orthotopic liver transplant or postsurgical aCRT than for patients treated with dCRT. The excellent outcomes after nCRT/orthotopic liver transplant prov…
View article: Anorectal Manometry Profile among Patients with Chronic Constipation and Faecal Incontinence in Western India: A Retrospective Study
Anorectal Manometry Profile among Patients with Chronic Constipation and Faecal Incontinence in Western India: A Retrospective Study Open
Introduction: About 50% of patients referred to tertiary care centre for constipation in the western countries have faecal evacuation disorder. A diagnosis of faecal evacuation disorder requires specialised investigations such as anorectal…
View article: Corrigendum to: Center volume impact on graft survival and waitlist time in donation after circulatory death (DCD) liver transplantation in the United States
Corrigendum to: Center volume impact on graft survival and waitlist time in donation after circulatory death (DCD) liver transplantation in the United States Open