Arkadij Kummer
YOU?
Author Swipe
View article: The physiological landscape and specificity of antibody repertoires are consolidated by multiple immunizations
The physiological landscape and specificity of antibody repertoires are consolidated by multiple immunizations Open
Diverse antibody repertoires spanning multiple lymphoid organs (i.e., bone marrow, spleen, lymph nodes) form the foundation of protective humoral immunity. Changes in their composition across lymphoid organs are a consequence of B-cell sel…
View article: mtx-COBRA: Subcellular localization prediction for bacterial proteins
mtx-COBRA: Subcellular localization prediction for bacterial proteins Open
Background Bacteria can have beneficial effects on our health and environment; however, many are responsible for serious infectious diseases, warranting the need for vaccines against such pathogens. Bioinformatic and experimental technolog…
The Physiological Landscape and Specificity of Antibody Repertoires Open
Diverse antibody repertoires spanning multiple lymphoid organs (e.g., bone marrow, spleen, lymph nodes) form the foundation of protective humoral immunity. Changes in their composition across lymphoid organs are a consequence of B-cell sel…
Principled Decision-Making Workflow with Hierarchical Bayesian Models of High-Throughput Dose-Response Measurements Open
We present a case study applying hierarchical Bayesian estimation on high-throughput protein melting-point data measured across the tree of life. We show that the model is able to impute reasonable melting temperatures even in the face of …
Principled decision-making workflow with hierarchical Bayesian models of high throughput dose-response measurements Open
We present a case study applying hierarchical Bayesian estimation on high throughput protein melting point data measured across the tree of life. We show that the model is able to impute reasonable melting temperatures even in the face of …
Reimplementing Unirep in JAX Open
UniRep is a recurrent neural network model trained on 24 million protein sequences, and has shown utility in protein engineering. The original model, however, has rough spots in its implementation, and a convenient API is not available for…