Arkady M. Pertsov
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View article: Individualization of atrial tachycardia models for clinical applications: Performance of fiber-independent model
Individualization of atrial tachycardia models for clinical applications: Performance of fiber-independent model Open
One of the challenges in the development of patient-specific models of cardiac arrhythmias for clinical applications has been accounting for myocardial fiber organization. The fiber varies significantly from heart to heart, but cannot be d…
View article: Fiber Organization has Little Effect on Electrical Activation Patterns during Focal Arrhythmias in the Left Atrium.
Fiber Organization has Little Effect on Electrical Activation Patterns during Focal Arrhythmias in the Left Atrium. Open
Over the past two decades there has been a steady trend towards the development of realistic models of cardiac conduction with increasing levels of detail. However, making models more realistic complicates their personalization and use in …
View article: Fiber Organization Has Little Effect on Electrical Activation Patterns During Focal Arrhythmias in the Left Atrium
Fiber Organization Has Little Effect on Electrical Activation Patterns During Focal Arrhythmias in the Left Atrium Open
Over the past two decades there has been a steady trend towards the development of realistic models of cardiac conduction with increasing levels of detail. However, making models more realistic complicates their personalization and use in …
View article: Patient-Specific Heart Model Towards Atrial Fibrillation
Patient-Specific Heart Model Towards Atrial Fibrillation Open
Atrial fibrillation is a heart rhythm disorder that affects tens of millions people worldwide. The most effective treatment is catheter ablation. This involves irreversible heating of abnormal cardiac tissue facilitated by electroanatomica…
View article: Patient-specific heart model towards atrial fibrillation
Patient-specific heart model towards atrial fibrillation Open
Atrial fibrillation is a heart rhythm disorder that affects tens of millions\npeople worldwide. The most effective treatment is catheter ablation. This\ninvolves irreversible heating of abnormal cardiac tissue facilitated by\nelectroanatom…
View article: Atrial fibrillation source area probability mapping using electrogram patterns of multipole catheters
Atrial fibrillation source area probability mapping using electrogram patterns of multipole catheters Open
Background Catheter ablation therapy involving isolation of pulmonary veins (PVs) from the left atrium is performed to terminate atrial fibrillation (AF). Unfortunately, standalone PV isolation procedure has shown to be a suboptimal succes…
View article: Locating Atrial Fibrillation Rotor and Focal Sources Using Iterative Navigation of Multipole Diagnostic Catheters
Locating Atrial Fibrillation Rotor and Focal Sources Using Iterative Navigation of Multipole Diagnostic Catheters Open
The algorithm could play a critical role in clinical electrophysiology laboratories for mapping patient-specific ablation of AF sources located outside the pulmonary veins and improving the procedure success.
View article: Iterative navigation of multipole diagnostic catheters to locate repeating‐pattern atrial fibrillation drivers
Iterative navigation of multipole diagnostic catheters to locate repeating‐pattern atrial fibrillation drivers Open
Introduction Targeting repeating‐pattern atrial fibrillation (AF) sources (reentry or focal drivers) can help in patient‐specific ablation therapy for AF; however, the development of reliable and accurate tools for locating such sources re…
View article: Developing an Iterative Tracking Algorithm to Guide a Catheter Towards Atrial Fibrillation Rotor Sources in Simulated Fibrotic Tissue
Developing an Iterative Tracking Algorithm to Guide a Catheter Towards Atrial Fibrillation Rotor Sources in Simulated Fibrotic Tissue Open
Locating atrial fibrillation (AF) rotor sources can help target ablation therapy for AF. Our aim was to develop a catheter-tracking algorithm to locate AF rotor sources using a conventional 20-electrode circular catheter. We simulated roto…
View article: Determining the light scattering and absorption parameters from forward-directed flux measurements in cardiac tissue
Determining the light scattering and absorption parameters from forward-directed flux measurements in cardiac tissue Open
We describe a method to accurately measure the light scattering model parameters from forward-directed flux (FDF) measurements carried out with a fiber-optic probe (optrode). Improved determination of light scattering parameters will, in t…
View article: A novel catheter-guidance algorithm for localization of atrial fibrillation rotor and focal sources
A novel catheter-guidance algorithm for localization of atrial fibrillation rotor and focal sources Open
Locating atrial fibrillation (AF) focal and rotor sources can help improve target ablation therapy for AF. However, it remains unclear how to use the information provided by multi-polar diagnostic catheters (MPDC) to locate AF sources. Our…
View article: Catheter simulator software tool to generate electrograms of any multi-polar diagnostic catheter from 3D atrial tissue
Catheter simulator software tool to generate electrograms of any multi-polar diagnostic catheter from 3D atrial tissue Open
Simulations are excellent tools for assessing new therapeutic strategies and are often conducted before implementing new therapy options in a clinical practice. For patients suffering from a heart arrhythmia, the main source of information…
View article: Cardiac Response to Low-Energy Field Pacing Challenges the Standard Theory of Defibrillation
Cardiac Response to Low-Energy Field Pacing Challenges the Standard Theory of Defibrillation Open
Background— The electric response of myocardial tissue to periodic field stimuli has attracted significant attention as the basis for low-energy antifibrillation pacing, potentially more effective than traditional single high-energy shocks…
View article: Evolution of Action Potential Alternans in Rabbit Heart during Acute Regional Ischemia
Evolution of Action Potential Alternans in Rabbit Heart during Acute Regional Ischemia Open
This study investigates the development of the spatiotemporal pattern of action potential alternans during acute regional ischemia. Experiments were carried out in isolated Langendorff-perfused rabbit heart using a combination of optical m…
View article: Characterization of Electrograms from Multipolar Diagnostic Catheters during Atrial Fibrillation
Characterization of Electrograms from Multipolar Diagnostic Catheters during Atrial Fibrillation Open
Atrial fibrillation (AF) is the most common arrhythmia in USA with more than 2.3 million people affected annually. Catheter ablation procedure is a method for treatment of AF, which involves 3D electroanatomic mapping of the patient's left…