Armaghan Shafaei
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View article: Cruciferous vegetables improve glycaemic control compared to root/squash vegetables in a randomized, controlled, crossover trial: The <scp>VEgetableS</scp> for <scp>vaScular hEaLth</scp> ( <scp>VESSEL</scp> ) study
Cruciferous vegetables improve glycaemic control compared to root/squash vegetables in a randomized, controlled, crossover trial: The <span>VEgetableS</span> for <span>vaScular hEaLth</span> ( <span>VESSEL</span> ) study Open
Aims Higher cruciferous vegetable (e.g., broccoli) intake is associated with lower risk of type 2 diabetes and cardiovascular disease, but limited causal evidence exists. We investigated if cruciferous vegetable intake improved glycaemic c…
View article: What are the best cooking methods to retain sulfur-containing compounds in cruciferous vegetables?
What are the best cooking methods to retain sulfur-containing compounds in cruciferous vegetables? Open
Observational studies suggest higher intake of cruciferous vegetables (e.g., broccoli, cauliflower, kale) is associated with lower chronic disease risk (1,2) . Glucosinolates (GSL) and cysteine sulfoxides such as S- methyl cysteine sulfoxi…
View article: S-methyl-L-cysteine sulfoxide and glucosinolate levels in Australian-sourced Brassica vegetables before and after domestic cooking
S-methyl-L-cysteine sulfoxide and glucosinolate levels in Australian-sourced Brassica vegetables before and after domestic cooking Open
Currently no data exists on S-methyl-L-cysteine sulfoxide (SMCSO) levels in Australian-sourced vegetables and limited data exists for glucosinolates. The effect of various cooking methods on the retention of SMCSO and glucosinolates in Aus…
View article: Cruciferous vegetables lower blood pressure in adults with mildly elevated blood pressure in a randomized, controlled, crossover trial: the VEgetableS for vaScular hEaLth (VESSEL) study
Cruciferous vegetables lower blood pressure in adults with mildly elevated blood pressure in a randomized, controlled, crossover trial: the VEgetableS for vaScular hEaLth (VESSEL) study Open
Background Higher cruciferous vegetable intake is associated with lower cardiovascular disease risk in observational studies. The pathways involved remain uncertain. We aimed to determine whether cruciferous vegetable intake (active) lower…
View article: S‐Methyl Cysteine Sulfoxide Does Not Ameliorate Weight Gain or Hyperlipidemia in Mice Fed a High‐Fat Diet
S‐Methyl Cysteine Sulfoxide Does Not Ameliorate Weight Gain or Hyperlipidemia in Mice Fed a High‐Fat Diet Open
Scope Higher intake of cruciferous and allium vegetables is associated with lower cardiometabolic risk. Little research has investigated the cardiometabolic effects of S‐methyl cysteine sulfoxide (SMCSO), found abundant in these vegetables…
View article: Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis Open
Obesity is in epidemic proportions in many parts of the world, contributing to increasing rates of non-alcoholic fatty liver disease (NAFLD). NAFLD represents a range of conditions from the initial stage of fatty liver to non-alcoholic ste…
View article: Development of a food composition database for the estimation of dietary S-methyl cysteine sulfoxide from vegetables
Development of a food composition database for the estimation of dietary S-methyl cysteine sulfoxide from vegetables Open
View article: Simultaneous extraction and quantitative analysis of S-Methyl-l-Cysteine Sulfoxide, sulforaphane and glucosinolates in cruciferous vegetables by liquid chromatography mass spectrometry
Simultaneous extraction and quantitative analysis of S-Methyl-l-Cysteine Sulfoxide, sulforaphane and glucosinolates in cruciferous vegetables by liquid chromatography mass spectrometry Open
View article: S-methyl cysteine sulfoxide and its potential role in human health: a scoping review
S-methyl cysteine sulfoxide and its potential role in human health: a scoping review Open
Higher intakes of cruciferous and allium vegetables are associated with a lower risk of cardiometabolic-related outcomes in observational studies. Whilst acknowledging the many healthy compounds within these vegetables, animal studies indi…
View article: S-methyl cysteine sulfoxide and its potential role in human health: a scoping review
S-methyl cysteine sulfoxide and its potential role in human health: a scoping review Open
Higher intakes of cruciferous and allium vegetables are associated with a lower risk of cardiometabolic-related outcomes in observational studies. Whilst acknowledging the many healthy compounds within these vegetables, animal studies indi…
View article: Development of Nanoliposome of Labisia pumila Standardized Extract
Development of Nanoliposome of Labisia pumila Standardized Extract Open
Background: Labisia pumila Labisia pumila Labisia pumila Labisia pumila Labisia pumila Labisia pumila Labisia pumila Labisia pumila Labisia pumila has been used traditionally for the treatment of several ailments such as gonorrhoea, dysmen…
View article: Sulfur compounds: From plants to humans and their role in chronic disease prevention
Sulfur compounds: From plants to humans and their role in chronic disease prevention Open
Sulfur is essential for the health of plants and is an indispensable dietary component for human health and disease prevention. Its incorporation into our food supply is heavily reliant upon the uptake of sulfur into plant tissue and our s…
View article: Sensitive and quantitative determination of short-chain fatty acids in human serum using liquid chromatography mass spectrometry
Sensitive and quantitative determination of short-chain fatty acids in human serum using liquid chromatography mass spectrometry Open
View article: Data supporting development and validation of liquid chromatography tandem mass spectrometry method for the quantitative determination of bile acids in feces
Data supporting development and validation of liquid chromatography tandem mass spectrometry method for the quantitative determination of bile acids in feces Open
View article: Pharmacokinetics and antiangiogenic studies of potassium koetjapate in rats
Pharmacokinetics and antiangiogenic studies of potassium koetjapate in rats Open
The results indicate that bioabsorption of KKA from oral route was considerably efficient with longer retention in body than compared to that of the intravenous route. Further, improved antiangiogenic activity of KKA was recorded which cou…
View article: Anti-Uterine Fibroid Effect of Standardized Labisia Pumila Var. Alata Extracts In Vitro and in Human Uterine Fibroid Cancer Xenograft Model
Anti-Uterine Fibroid Effect of Standardized Labisia Pumila Var. Alata Extracts In Vitro and in Human Uterine Fibroid Cancer Xenograft Model Open
This work provide significant data of the potential of L. pumila in management of uterine fibroids..
View article: Zwitterionic HILIC tandem mass spectrometry with isotope dilution for rapid, sensitive and robust quantification of pyridine nucleotides in biological extracts
Zwitterionic HILIC tandem mass spectrometry with isotope dilution for rapid, sensitive and robust quantification of pyridine nucleotides in biological extracts Open
The pyridine nucleotides nicotineamide adenine dinucleotide (NAD) and nicotineamide adenine dinucleotide phosphate (NADP) are conserved coenzymes across all domains of life, and are involved in more than 200 different hydride transfer reac…
View article: Zwitterionic HILIC tandem mass spectrometry with isotope dilution for rapid, sensitive and robust quantification of pyridine nucleotides in biological extracts
Zwitterionic HILIC tandem mass spectrometry with isotope dilution for rapid, sensitive and robust quantification of pyridine nucleotides in biological extracts Open
View article: Establishment of in vitro and in vivo anti-colon cancer efficacy of essential oils containing oleo-gum resin extract of Mesua ferrea
Establishment of in vitro and in vivo anti-colon cancer efficacy of essential oils containing oleo-gum resin extract of Mesua ferrea Open
Proven the great potential of essential oils as anticancer agents, the current study intended to explore molecular mechanisms responsible for in vitro and in vivo anti-colon cancer efficacy of essential oil containing oleo-gum resin extrac…
View article: Application of high performance liquid chromatography and Fourier-transform infrared spectroscopy techniques for evaluating the stability of Orthosiphon aristatus ethanolic extract and its nano liposomes
Application of high performance liquid chromatography and Fourier-transform infrared spectroscopy techniques for evaluating the stability of Orthosiphon aristatus ethanolic extract and its nano liposomes Open
Orthosiphon aristatus (Blume) Miq., Lamiaceae, is a medicinal plant from Southeast Asia. Pharmacological effects of O. aristatus are attributed to the presence of lipophilic flavones. This study aimed to carry out accelerated stability stu…
View article: Standardization of Orthoshiphon stamineus Raw Material and Extracts for Anti-Uterine Fibroid
Standardization of Orthoshiphon stamineus Raw Material and Extracts for Anti-Uterine Fibroid Open
This study aim to evaluate gravimetric parameters and physicochemical of raw materials of Orthosiphon stamineus in order to ascertain the quality of plant materials and achieved standardized material. Anti-uterine fibroid potential was inv…
View article: Preclinical safety assessment and mutagenicity of the hydroethanolic extract of <em>Syzygium campanulatum</em> leaves.
Preclinical safety assessment and mutagenicity of the hydroethanolic extract of <em>Syzygium campanulatum</em> leaves. Open
Syzygium campanulatum (Myrtaceae) is a species indigenous to Southeast Asia, a widely consumed medicinal herb and rich in phytochemical content and notable antiangiogenic and anti-colon cancer. Safety reports of administration of S. campan…
View article: PHARMACOKINETICS AND BIOAVAILABILITY OF ORTHOSIPHON STAMINEUS ETHANOLIC EXTRACT AND ITS-NANO LIPOSOMES IN SPRAGUE-DAWLEY RATS
PHARMACOKINETICS AND BIOAVAILABILITY OF ORTHOSIPHON STAMINEUS ETHANOLIC EXTRACT AND ITS-NANO LIPOSOMES IN SPRAGUE-DAWLEY RATS Open
Objective: This study aimed to perform pharmacokinetic profile of rosmarinic acid (RA), sinensitin (SIN), eupatorin (EUP) and 3΄-hydroxy-5,6,7,4΄-tetramethoxyflavone (TMF) in Orthosiphon stamineus ethan…
View article: Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study
Flavonoids-Rich Orthosiphon stamineus Extract as New Candidate for Angiotensin I-Converting Enzyme Inhibition: A Molecular Docking Study Open
This study aims to evaluate the in vitro angiotensin-converting enzyme (ACE) inhibition activity of different extracts of Orthosiphon stamineus (OS) leaves and their main flavonoids, namely rosmarinic acid (RA), sinensetin (SIN), eupatorin…
View article: Genotoxicity, acute and subchronic toxicity studies of nano liposomes of Orthosiphon stamineus ethanolic extract in Sprague Dawley rats
Genotoxicity, acute and subchronic toxicity studies of nano liposomes of Orthosiphon stamineus ethanolic extract in Sprague Dawley rats Open