Hadi D. Arman
YOU?
Author Swipe
View article: Enantioconvergent Access to Chiral S(VI) Stereocenters by Kinetic Resolution of Sulfonimidoyl Chlorides
Enantioconvergent Access to Chiral S(VI) Stereocenters by Kinetic Resolution of Sulfonimidoyl Chlorides Open
Sulfur chirality has recently gained in importance across a wide range of chemical domains. However, the dearth of catalytic approaches for sulfur(VI) stereocenters continues to present a challenge for the broader utilization of chiral‐at‐…
View article: Enantioconvergent Access to Chiral S(VI) Stereocenters by Kinetic Resolution of Sulfonimidoyl Chlorides
Enantioconvergent Access to Chiral S(VI) Stereocenters by Kinetic Resolution of Sulfonimidoyl Chlorides Open
Sulfur chirality has recently gained in importance across a wide range of chemical domains. However, the dearth of catalytic approaches for sulfur(VI) stereocenters continues to present a challenge for the broader utilization of chiral‐at‐…
View article: Reduced Cobalt Corroles: Isolation, Reactivity, and Electronic Structure
Reduced Cobalt Corroles: Isolation, Reactivity, and Electronic Structure Open
Chemical reduction of [CoIII(py)2(TPC)] (TPC = trianion of 5,10,15-triphenylcorrole) with one or two molar equivalents of KC8 or Na(Hg) generates the reduced cobalt corrolate species, [CoII(TPC)]…
View article: The Synthesis of 1beta-Hydroxytestosterone, a Testosterone Metabolite of Xenobiotic Human Cytochrome P450 Enzymes from a Borylation of Androsta-1,4-diene-3,17-dione
The Synthesis of 1beta-Hydroxytestosterone, a Testosterone Metabolite of Xenobiotic Human Cytochrome P450 Enzymes from a Borylation of Androsta-1,4-diene-3,17-dione Open
Xenobiotic cytochrome P450 enzymes have been shown to hydroxylate testosterone at various positions in the steroid backbone including 1beta-hydroxytestosterone. Despite the potential application to study the biochemistry of these enzymes, …
View article: Construction of sulfur stereocenters by asymmetric geminate recasting
Construction of sulfur stereocenters by asymmetric geminate recasting Open
The reactions of radical pairs formed by light- or heat-induced homolysis are of fundamental importance to many biochemical processes, as well as production of pharmaceuticals, industrial chemicals, and polymers. For chiral compounds, clea…
View article: Photolytic Access to Oxaspirodecanes and Chromenes from Vinyldiazo Ester Cycloaddition with p-Quinones. A Vinylcarbene is not Involved
Photolytic Access to Oxaspirodecanes and Chromenes from Vinyldiazo Ester Cycloaddition with p-Quinones. A Vinylcarbene is not Involved Open
Synthetic methods that provide access to skeletally diverse heterocyclic motifs are poised to accelerate drug discovery and streamline synthesis of advanced intermediates and materials. However, the development of such synthetic methods ne…
View article: A synthesis of 1β-hydroxytestosterone, a metabolite of xenobiotic human cytochrome P450 enzymes, beginning with a borylation of boldione
A synthesis of 1β-hydroxytestosterone, a metabolite of xenobiotic human cytochrome P450 enzymes, beginning with a borylation of boldione Open
An 8-step synthesis of 1β-hydroxytestosterone was accomplished beginning with a conjugate borylation reaction of boldione.
View article: Effects of Neutral and Charged Tectons on the Hydrogen-Bonded Network and Crystal Packing of N,Nʹ-bis(phosphonomethyl)-1,4,5,8-naphthalenediimide
Effects of Neutral and Charged Tectons on the Hydrogen-Bonded Network and Crystal Packing of N,Nʹ-bis(phosphonomethyl)-1,4,5,8-naphthalenediimide Open
View article: Correction to Linker Engineering toward Tunable Emission Behavior of Porous Interpenetrated Zr-Organic Frameworks
Correction to Linker Engineering toward Tunable Emission Behavior of Porous Interpenetrated Zr-Organic Frameworks Open
View article: Multimodal Acridine Photocatalysis Enables Direct Access to Thiols from Carboxylic Acids and Elemental Sulfur
Multimodal Acridine Photocatalysis Enables Direct Access to Thiols from Carboxylic Acids and Elemental Sulfur Open
Development of photocatalytic systems that facilitate mechanistically divergent steps in complex catalytic manifolds by distinct activation modes can enable previously inaccessible synthetic transformations. However, multimodal photocataly…
View article: Acridine Photocatalysis Enables Tricomponent Direct Decarboxylative Amine Construction
Acridine Photocatalysis Enables Tricomponent Direct Decarboxylative Amine Construction Open
Amines are centrally important motifs in medicinal chemistry and biochemistry, and indispensable intermediates and linchpins in organic synthesis. Despite their cross-disciplinary prominence, synthetic access to amine continues to rely on …
View article: Multimodal Acridine Photocatalysis Enables Direct Access to Thiols from Carboxylic Acids and Elemental Sulfur
Multimodal Acridine Photocatalysis Enables Direct Access to Thiols from Carboxylic Acids and Elemental Sulfur Open
Development of photocatalytic systems that facilitate mechanistically different steps in complex catalytic manifolds by distinct activation modes can enable previously inaccessible synthetic transformations. However, multimodal photocataly…
View article: Aquabis(2,2′-bipyridine-κ<sup>2</sup> <i>N</i>,<i>N</i>′)(isonicotinamide-κ<i>N</i>)ruthenium(II) bis(trifluoromethanesulfonate)
Aquabis(2,2′-bipyridine-κ<sup>2</sup> <i>N</i>,<i>N</i>′)(isonicotinamide-κ<i>N</i>)ruthenium(II) bis(trifluoromethanesulfonate) Open
In the title complex, [Ru(C 10 H 8 N 2 ) 2 (C 6 H 6 N 2 O)(H 2 O)](CF 3 SO 3 ) 2 , the central Ru II atom is sixfold coordinated by two bidentate 2,2′-bipyridine, an isonicotinamide ligand, and a water molecule in a distorted octahedral en…
View article: (2,2′-Bipyridine-κ<sup>2</sup> <i>N</i>,<i>N</i>′)(4,4′-dimethoxy-2,2′-bipyridine-κ<sup>2</sup> <i>N</i>,<i>N</i>′)palladium(II) bis(trifluoromethanesulfonate)
(2,2′-Bipyridine-κ<sup>2</sup> <i>N</i>,<i>N</i>′)(4,4′-dimethoxy-2,2′-bipyridine-κ<sup>2</sup> <i>N</i>,<i>N</i>′)palladium(II) bis(trifluoromethanesulfonate) Open
In the title complex salt, [Pd(C 10 H 8 N 2 )(C 12 H 12 N 2 O 2 )](CF 3 SO 3 ) 2 , the palladium(II) atom is fourfold coordinated by two chelating ligands, 2,2′-bipyridine and 4,4′-dimethoxy-2,2′-bipyridine, in a distorted square-planar en…
View article: Bis[2,6-bis(benzimidazol-2-yl)pyridine-κ<sup>3</sup> <i>N</i>,<i>N</i>′,<i>N</i>′′]nickel(II) bis(trifluoromethanesulfonate) diethyl ether monosolvate
Bis[2,6-bis(benzimidazol-2-yl)pyridine-κ<sup>3</sup> <i>N</i>,<i>N</i>′,<i>N</i>′′]nickel(II) bis(trifluoromethanesulfonate) diethyl ether monosolvate Open
In the title complex, [Ni(C 19 H 13 N 5 ) 2 ](CF 3 SO 3 ) 2 ·(CH 3 CH 2 ) 2 O, the central Ni II atom is sixfold coordinated by three nitrogen atoms of each 2,6-bis(2-benzimidazolyl)pyridine ligand in a distorted octahedral geometry with t…
View article: CCDC 2324427: Experimental Crystal Structure Determination
CCDC 2324427: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Dichlorido(4,7-dimethoxy-1,10-phenanthroline-κ<sup>2</sup> <i>N</i>,<i>N</i>′)zinc(II)
Dichlorido(4,7-dimethoxy-1,10-phenanthroline-κ<sup>2</sup> <i>N</i>,<i>N</i>′)zinc(II) Open
In the title complex, [ZnCl 2 (C 14 H 12 N 2 O 2 )], the Zn II atom is located on a twofold rotation axis and is fourfold coordinated by two chlorido ligands and a bidentate 4,7-methoxy-1,10-phenanthroline ligand in a distorted tetrahedral…
View article: Acridine photocatalysis enables tricomponent direct decarboxylative amine construction
Acridine photocatalysis enables tricomponent direct decarboxylative amine construction Open
Diverse amines and amino acids are now readily accessed from carboxylic acids, aldehydes, and amine precursors in a direct decarboxylative reaction enabled by a homogeneous triple catalytic system based on acridine photocatalysis.
View article: Peptide recognition by a synthetic receptor at subnanomolar concentrations
Peptide recognition by a synthetic receptor at subnanomolar concentrations Open
The synthetic receptor cucurbit[8]uril (Q8) binds the N-terminal dipeptide site Lys-Phe with subnanomolar affinity in neutral aqueous buffer.
View article: Denitrogenative dismantling of heteroaromatics by nucleophilic substitution reactions with diazomethyl compounds
Denitrogenative dismantling of heteroaromatics by nucleophilic substitution reactions with diazomethyl compounds Open
We report divergent reactions of 1,2,3-triazines and 1,2,3-triazine 1-oxides with diazomethyl compounds, the former yielding diazovinylketoesters, and the latter giving rise to pyrazole derivatives through extrusion of ethyl cyanocarboxyla…
View article: Photoinduced [4 + 2]-cycloaddition reactions of vinyldiazo compounds for the construction of heterocyclic and bicyclic rings
Photoinduced [4 + 2]-cycloaddition reactions of vinyldiazo compounds for the construction of heterocyclic and bicyclic rings Open
Under blue light vinyldiazoacetate reagents selectively form unstable cyclopropenes that undergo intermolecular cycloaddition reactions at a faster rate than their competitive ene dimerization.
View article: The “cesium effect” magnified: exceptional chemoselectivity in cesium ion mediated nucleophilic reactions
The “cesium effect” magnified: exceptional chemoselectivity in cesium ion mediated nucleophilic reactions Open
Synthetically challenging pyridones and pyridylpyridones can now be readily accessed from simple precursors in a chemodivergent oxadiaza excision cross-coupling enabled by an unprecedented conformational accommodation-driven cesium effect.
View article: Accessing Thiols Directly from Carboxylic Acids and Elemental Sulfur by Multimodal Acridine Photocatalysis
Accessing Thiols Directly from Carboxylic Acids and Elemental Sulfur by Multimodal Acridine Photocatalysis Open
The thiol group is one of the most biologically important and synthetically versatile organosulfur functionalities that can serve as a central entry point to a wide range of other sulfur-containing functional groups. Despite their cross-di…
View article: CCDC 2114169: Experimental Crystal Structure Determination
CCDC 2114169: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2170584: Experimental Crystal Structure Determination
CCDC 2170584: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2170582: Experimental Crystal Structure Determination
CCDC 2170582: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2176484: Experimental Crystal Structure Determination
CCDC 2176484: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2170581: Experimental Crystal Structure Determination
CCDC 2170581: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2170585: Experimental Crystal Structure Determination
CCDC 2170585: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2170572: Experimental Crystal Structure Determination
CCDC 2170572: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …