Explanipedia

General Surgery and Kidney Transplantation Open

G. Peluso, Nicola Carlomagno, Alessandro Scotti, Akbar Jamshidi, Vincenzo Cerbone , et al. · 2025

Achalasia and Thyroid Disorders: A Hidden Autoimmune Overlap? Epidemiology, Mechanisms, and Clinical Relevance of an Emerging Association Open

Agostino Fernicola, Armando Calogero, Felice Crocetto, Giacomo Capece, Guido Bocchino , et al. · 2025

Background: Achalasia is a rare primary esophageal motility disorder characterized by impaired lower esophageal sphincter relaxation and progressive loss of peristalsis. Although its pathogenesis remains incompletely understood, autoimmune…

Surgical Reconstruction of Abdominal Wall Endometriosis Post-Cesarean Section: A Monocentric Experience of a Rare Pathology Open

Agostino Fernicola, Armando Calogero, G. Peluso, Alfonso Santangelo, Domenico Santangelo , et al. · 2025

Background: Abdominal wall endometriosis (AWE) is a rare pathological condition that mostly occurs in the post-cesarean section. This study aimed to describe the surgical approach employed in treating 31 patients at our center over the pas…

Achalasia and Gut Microbiota: Is Dysbiosis an Overlooked Factor in Postoperative Surgical Outcomes? Open

Agostino Fernicola, Giuseppe Palomba, Armando Calogero, Antonella Sciarra, Annachiara Cavaliere , et al. · 2025

Background: Esophageal achalasia is a rare motility disorder characterized by impaired lower esophageal sphincter (LES) relaxation and food stasis. Surgical interventions, including Heller myotomy with fundoplication or peroral endoscopic …

Nuck Cyst, an Unexpected Amethyst Gem in the Inguinal Canal: A Case Report and Literature Review Open

Agostino Fernicola, Armando Calogero, Giuseppe Palomba, George H. Petti, Mario Pochet , et al. · 2025

AIM: Nuck cyst is rare female saccular hydroceles. It appears at birth or months or years later in adulthood, resulting from imperfect closure of the canal of Nuck. Its diagnosis is often incorrect and confused with an inguinal or femoral …

Dark Topics on Giant Retroperitoneal Liposarcoma: A Systematic Review of 157 Cases Open

Alfonso Santangelo, Agostino Fernicola, Domenico Santangelo, G. Peluso, Armando Calogero , et al. · 2025

Background/Objectives: Giant Retroperitoneal Liposarcomas (giant RPLs) represent a rare malignant disease of adulthood that does not yet have a univocal definition in the scientific literature. The symptoms may be late, depending on the po…

The Role of Butirprost® as an Adjuvant in Enhancing the Effect of Antibiotics in Patients Affected by Chronic Bacterial Prostatitis: A Randomized Prospective Trial Open

Felice Crocetto, Armando Calogero, Michele Santangelo, Agostino Fernicola, Filippo Varlese , et al. · 2025

Bacterial prostatitis (BP) is a common prostatic infection characterized by pain and urinary symptoms, often with negative bacterial cultures from prostatic secretions. It affects young and older men bimodally and impacts quality of life (…

Endoscopic Sleeve Gastroplasty for the Treatment of Obesity: A Single-Centre Experience and Literature Review Open

Agostino Fernicola, Giuseppe Palomba, Armando Calogero, Michele Santangelo, Alessandro Salvucci , et al. · 2024

ESG was an effective, reversible, and repeatable surgical procedure for bariatric patients.

Theodor Billroth: The Pioneer Gastrectomy Surgeon and His Contributions to the Evolution of General Surgery Open

Agostino Fernicola, Armando Calogero, Michele Santangelo · 2024

Advances in Urinary Diversion: From Cutaneous Ureterostomy to Orthotopic Neobladder Reconstruction—A Comprehensive Review Open

Biagio Barone, Luigi Napolitano, Pasquale Reccia, Francesco Paolo Calace, Luigi De Luca , et al. · 2024

Bladder cancer ranks as the 10th most prevalent cancer globally with an increasing incidence. Radical cystectomy combined with urinary diversion represents the standard treatment for muscle-invasive bladder cancer, offering a range of tech…

Unlocking Precision Medicine: Liquid Biopsy Advancements in Renal Cancer Detection and Monitoring Open

Felice Crocetto, Alfonso Falcone, Benito Fabio Mirto, Enrico Sicignano, Giovanni Pagano , et al. · 2024

Renal cell carcinoma (RCC) remains a formidable diagnostic challenge, especially in the context of small renal masses. The quest for non-invasive screening tools and biomarkers has steered research towards liquid biopsy, focusing on microR…

Multidisciplinary Approach to the Diagnosis and Therapy of Mycosis Fungoides Open

Paola Vitiello, Caterina Sagnelli, Andrea Ronchi, Renato Franco, Stefano Caccavale , et al. · 2023

Mycosis fungoides is the most common primary cutaneous T-cell lymphoma, characterized by skin-homing CD4+ T cells derivation, indolent course, and low-grade of malignancy. Mycosis fungoides’s classic type typically onsets with cutaneous er…

Dyslipidemia in Transplant Patients: Which Therapy? Open

Gabriella Iannuzzo, Gianluigi Cuomo, Anna Di Lorenzo, Maria Tripaldella, Vania Mallardo , et al. · 2022

Cardiovascular disease is the most important cause of death worldwide in recent years; an increasing trend is also shown in organ transplant patients subjected to immunosuppressive therapies, in which cardiovascular diseases represent one …

Epidemiological and clinical aspects of hepatitis B virus infection in Italy over the last 50 years Open

Caterina Sagnelli, Antonello Sica, Massimiliano Creta, Armando Calogero, Massimo Ciccozzi , et al. · 2022

A relevant gradual reduction of both the incidence rate of acute hepatitis B (AHB) and prevalence of chronic hepatitis B has occurred in Italy in the last 50 years, due to substantial epidemiological changes: Improvement in socioeconomic a…

Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence Open

Giuseppe Celentano, Massimiliano Creta, Luigi Napolitano, Marco Abate, Roberto La Rocca , et al. · 2022

The management of patients with prostate cancer (PCa) and previous or synchronous colorectal cancer (CRC) represents a challenging issue. A systematic review was performed in May 2022 to summarize available evidence about the diagnosis, ma…

Immune Checkpoint Inhibitors as a Neoadjuvant/Adjuvant Treatment of Muscle-Invasive Bladder Cancer: A Systematic Review Open

Biagio Barone, Armando Calogero, Luca Scafuri, Matteo Ferro, Giuseppe Lucarelli , et al. · 2022

Bladder cancer is the ninth most common cancer worldwide. Over 75% of non-muscle invasive cancer patients require conservative local treatment, while the remaining 25% of patients undergo radical cystectomy or radiotherapy. Immune checkpoi…

Metastasis-Directed Radiation Therapy with Consolidative Intent for Oligometastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis Open

Nicola Longo, Giuseppe Celentano, Luigi Napolitano, Roberto La Rocca, Marco Capece , et al. · 2022

The management of patients with oligometastatic urothelial carcinoma (UC) represents an evolving field in uro-oncology, and the role of metastasis-directed therapies, including metastasectomy and metastasis-directed radiation therapy (MDRT…

Promoting Laparoscopic Anterior Approach for a Very Low Presacral Primary Neuroendocrine Tumor Arising in a Tailgut Cyst Open

Maria Michela Di Nuzzo, Carlo De Werra, Mirella Pace, Raduan Ahmed Franca, Maria DʼArmiento , et al. · 2022

Background: Tailgut cysts are rare congenital lesions that develop in the presacral space. As they can potentially conceal primary neuroendocrine tumors, surgical excision is suggested as the treatment of choice. However, specific manageme…

Epithelioid Hemangioma of the Nose: A Challenging Diagnosis Open

Fabrizio Schönauer, Annachiara Cavaliere, Giuseppe Pezone, Armando Calogero, Caterina Sagnelli , et al. · 2022

Epithelioid hemangioma is a rare reactive vasoproliferative disease presenting with painless vascular nodules in the dermal and subcutaneous tissues of the head and neck. Clinical diagnosis can be difficult as, in most cases, the only symp…

Cardiovascular adverse events in patients with kidney cancer receiving combination of angiogenesis inhibitors plus immune checkpoint inhibitors vs. angiogenesis inhibitors vs. immune checkpoint inhibitors: a network analysis of randomized controlled trials. Open

Felice Crocetto, Carlo Buonerba, Luca Bardi, Antonio Verde, Simone Cilio , et al. · 2021

Cardiovascular adverse events in patients with kidney cancer receiving

COVID-19 and Prostate Cancer: a Complex Scenario With Multiple Facets Open

Felice Crocetto, Luciana Buonerba, Luca Scafuri, Vincenzo Caputo, Biagio Barone , et al. · 2021

Future Science OAVol. 8, No. 1 EditorialOpen AccessCOVID-19 and prostate cancer: a complex scenario with multiple facetsFelice Crocetto, Luciana Buonerba, Luca Scafuri, Vincenzo Caputo, Biagio Barone, Antonella Sciarra, Antonio Verde, Arma…

Renal involvement in COVID-19: focus on kidney transplant sector Open

Caterina Sagnelli, Antonello Sica, Monica Gallo, G. Peluso, Filippo Varlese , et al. · 2021

Fournier’s Gangrene in Patients with Oncohematological Diseases: A Systematic Review of Published Cases Open

Massimiliano Creta, Antonello Sica, Luigi Napolitano, Giuseppe Celentano, Roberto La Rocca , et al. · 2021

Patients suffering from hematological malignancies are at increased risk of Fournier’s gangrene (FG) due to immunosuppression caused by the disease itself or by disease-related treatments. A systematic review of PubMed, ISI Web of Knowledg…

SARS‐CoV‐2 infection affects the lower urinary tract and male genital system: A systematic review Open

Massimiliano Creta, Caterina Sagnelli, Giuseppe Celentano, Luigi Napolitano, Roberto La Rocca , et al. · 2021

PubMed, Scopus, and ISI Web of Knowledge databases were searched to identify studies published up to December 2020 on the involvement of urinary and male genital systems in COVID‐19. Sixteen studies involving a total of 575 patients (538 m…

How Fear of COVID-19 Can Affect Treatment Choices for Anaplastic Large Cell Lymphomas ALK+ Therapy: A Case Report Open

Antonello Sica, Caterina Sagnelli, Beniamino Casale, Gino Svanera, Massimiliano Creta , et al. · 2021

Background: The t (2; 5) chromosomal rearrangement of the ALK gene with nucleophosmin 1 gene (NPM1), resulting in an NPM1–ALK fusion, was first demonstrated in 1994 in anaplastic large cell lymphoma, (ALCL), a T-cell lymphoma responsive to…

How Fear of COVID-19 Can Affect Treatment Choices for Anaplastic Large Cell Lymphomas Alk+ Therapy: A Case Report Open

Antonello Sica, Caterina Sagnelli, Beniamoni Casale, Gino Svaneta, Massimiliano Creta , et al. · 2021

Background: The t (2; 5) chromosomal rearrangement and resulting nucleophosmin (NPM1) -ALK fusion was first observed in 1994 in anaplastic large cell lymphoma (ALCL), a T-cell lymphoma responsive to cyclophosphamide, abriblastine, vincrist…

Precocious ischemia preceding bilateral adrenal hemorrhage: A case report Open

Roberta Galatola, Michele Gambardella, Carmine Mollica, Armando Calogero, Mario Magliulo , et al. · 2020

An Anecdotal Case Report of Chronic Lymphatic Leukemia with del(11q) Treated with Ibrutinib: Artificial Nourishment and Physical Activity Program Open

Antonello Sica, Caterina Sagnelli, Alfonso Papa, Massimo Ciccozzi, Evangelista Sagnelli , et al. · 2020

Chronic lymphatic leukemia (CLL) is the most frequent type of leukemia in western countries and when association with del(11q) is correlated with a worse prognosis. We reported the clinical case of an 80-year-old patient with CLL related t…

Does Physical Activity Regulate Prostate Carcinogenesis and Prostate Cancer Outcomes? A Narrative Review Open

Marco Capece, Massimiliano Creta, Armando Calogero, Roberto La Rocca, Luigi Napolitano , et al. · 2020

Background: Prostate cancer (PCa) represents a common disease in men aged >65 years. The role of physical activity (PA) in patients at risk or diagnosed with PCa represents an evolving issue. We aimed to summarize available evidences about…

Endoscopic Treatment and Pulmonary Rehabilitation for Management of Lung Abscess in Elderly Lymphoma Patients Open

Roberto Cascone, Antonello Sica, Caterina Sagnelli, Annalisa Carlucci, Armando Calogero , et al. · 2020

Background: The management of lung abscess may be a challenge in elderly patients undergoing chemotherapy and/or radiotherapy for previous malignancy. Herein, we reported a case series of elderly patients with previous lymphoma undergoing …

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