Armando Puocci
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View article: Adipose-tumor crosstalk in colorectal cancer: Identifying (Epi)genetic biomarkers for tumor progression and cachexia
Adipose-tumor crosstalk in colorectal cancer: Identifying (Epi)genetic biomarkers for tumor progression and cachexia Open
View article: Bridging the gap between GLP1-receptor agonists and cardiovascular outcomes: evidence for the role of tirzepatide
Bridging the gap between GLP1-receptor agonists and cardiovascular outcomes: evidence for the role of tirzepatide Open
View article: Evidence that tirzepatide protects against diabetes-related cardiac damages
Evidence that tirzepatide protects against diabetes-related cardiac damages Open
View article: Tirzepatide prevents neurodegeneration through multiple molecular pathways
Tirzepatide prevents neurodegeneration through multiple molecular pathways Open
Background Several evidence demonstrated that glucagon-like peptide 1 receptor agonists (GLP1-RAs) reduce the risk of dementia in type 2 diabetes patients by improving memory, learning, and overcoming cognitive impairment. In this study, w…
View article: Myocardial sodium–glucose cotransporter <scp>2</scp> expression and cardiac remodelling in patients with severe aortic stenosis: The <scp>BIO‐AS</scp> study
Myocardial sodium–glucose cotransporter <span>2</span> expression and cardiac remodelling in patients with severe aortic stenosis: The <span>BIO‐AS</span> study Open
Aim Cardiac remodelling plays a major role in the prognosis of patients with aortic stenosis (AS) and could impact the benefits of aortic valve replacement. Our study aimed to evaluate the expression of sodium–glucose cotransporter 2 (SGLT…
View article: Targeting high glucose-induced epigenetic modifications at cardiac level: the role of SGLT2 and SGLT2 inhibitors
Targeting high glucose-induced epigenetic modifications at cardiac level: the role of SGLT2 and SGLT2 inhibitors Open
View article: Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists
Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists Open
Reactive oxygen species (ROS) have emerged as essential signaling molecules regulating cell survival, death, inflammation, differentiation, growth, and immune response. Environmental factors, genetic factors, or many pathological condition…
View article: Meccanismi comuni tra diabete e declino cognitivo
Meccanismi comuni tra diabete e declino cognitivo Open
The increased prevalence of diabetes (DM) constitutes a major public health problem, primarily due to its numerous comorbidity and complications. It is widely demonstrated that DM is a significant risk factor for the development of cogniti…
View article: Targeting High Glucose-Induced Epigenetic Modifications at Cardiac Levels: The Role of SGLT2 and SGLT2 Inhibitors
Targeting High Glucose-Induced Epigenetic Modifications at Cardiac Levels: The Role of SGLT2 and SGLT2 Inhibitors Open
Background: Sodium-glucose co-transporters inhibitors showed many beneficial effects at the cardiovascular level. Several mechanisms of action have been identified. However, no data are reported on their capability to act via epigenetic me…
View article: Anti-inflammatory role of SGLT2 inhibitors as part of their anti-atherosclerotic activity: Data from basic science and clinical trials
Anti-inflammatory role of SGLT2 inhibitors as part of their anti-atherosclerotic activity: Data from basic science and clinical trials Open
Atherosclerosis is a progressive inflammatory disease leading to mortality and morbidity in the civilized world. Atherosclerosis manifests as an accumulation of plaques in the intimal layer of the arterial wall that, by its subsequent eros…