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View article: Effect of nerve sparing gestures on oncological and functional outcomes during robotic-assisted radical prostatectomy
Effect of nerve sparing gestures on oncological and functional outcomes during robotic-assisted radical prostatectomy Open
View article: A Narrative Review of Treatment Options for Patients with Node-Positive Disease After Radical Prostatectomy: Current Evidence and Controversies
A Narrative Review of Treatment Options for Patients with Node-Positive Disease After Radical Prostatectomy: Current Evidence and Controversies Open
Purpose of Review: In approximately 10–15% of patients with prostate cancer (PCa), pathological lymph node metastases (pN1) are detected at radical prostatectomy (RP). The aim of this review is to describe the various treatment options for…
View article: The Role of Genomic Scores in the Management of Prostate Cancer Patients: A Comprehensive Narrative Review
The Role of Genomic Scores in the Management of Prostate Cancer Patients: A Comprehensive Narrative Review Open
Genomic score testing is increasingly being integrated into the management of prostate cancer (PCa) to overcome the limitations of traditional clinical and pathological parameters. Genomic tools will represent essential components of preci…
View article: Impact of <scp>three‐dimensional</scp> prostate models during robot‐assisted radical prostatectomy on surgical margins and functional outcomes
Impact of <span>three‐dimensional</span> prostate models during robot‐assisted radical prostatectomy on surgical margins and functional outcomes Open
Background Robot‐assisted radical prostatectomy (RARP) is the standard surgical procedure for the treatment of prostate cancer. RARP requires a trade‐off between performing a wider resection in order to reduce the risk of positive surgical…
View article: Impact of ISUP grade group on cancer-specific mortality in radical prostatectomy-treated prostate cancer patients with organ-confined disease
Impact of ISUP grade group on cancer-specific mortality in radical prostatectomy-treated prostate cancer patients with organ-confined disease Open
Introduction: We aimed to test the impact of International Society of Urological Pathology (ISUP) grade group (GG) on cancer-specific mortality (CSM) in organ-confined (pT2) prostate cancer (PCa) at radical prostatectomy (RP). Methods: RP …
View article: Established focal therapy—HIFU, IRE, or cryotherapy—where are we now?—a systematic review and meta-analysis
Established focal therapy—HIFU, IRE, or cryotherapy—where are we now?—a systematic review and meta-analysis Open
View article: Autologous Stem Cell Transplantation in HIVPositive and HIV-Negative Patients with Lymphoma: A Propensity Score Matched Comparative Analysis
Autologous Stem Cell Transplantation in HIVPositive and HIV-Negative Patients with Lymphoma: A Propensity Score Matched Comparative Analysis Open
Treatment of HIV-associated lymphoma (HIV-Ly) with autologous stem cell transplantation (ASCT) has shown a surprisingly low relapse rate in several series. The aim of this study was to compare the clinical outcomes of HIV-Ly and lymphomas …
View article: Reduction of surgical complications via 3D models during robotic assisted radical prostatectomy: review of current evidence and meta-analysis
Reduction of surgical complications via 3D models during robotic assisted radical prostatectomy: review of current evidence and meta-analysis Open
View article: Cost Analysis of Prostate Cancer Care Using a Biomarker-enhanced Diagnostic Strategy with Stockholm3
Cost Analysis of Prostate Cancer Care Using a Biomarker-enhanced Diagnostic Strategy with Stockholm3 Open
We explored different ways to detect prostate cancer more cost-effectively. We found that using a specific blood test, called Stockholm3, after a PSA (prostate-specific antigen) test to decide if an MRI scan (magnetic resonance imaging) is…
View article: Defining the optimal target-to-background ratio to identify positive lymph nodes in prostate cancer patients undergoing robot-assisted [99mTc]Tc-PSMA radioguided surgery: updated results and ad interim analyses of a prospective phase II study
Defining the optimal target-to-background ratio to identify positive lymph nodes in prostate cancer patients undergoing robot-assisted [99mTc]Tc-PSMA radioguided surgery: updated results and ad interim analyses of a prospective phase II study Open
View article: Systematic Review and Meta-Analysis of Salvage Ablation for Radiation-Recurrent Localized Prostate Cancer – A Focal Therapy Society Project
Systematic Review and Meta-Analysis of Salvage Ablation for Radiation-Recurrent Localized Prostate Cancer – A Focal Therapy Society Project Open
View article: Global Variation in Magnetic Resonance Imaging Quality of the Prostate
Global Variation in Magnetic Resonance Imaging Quality of the Prostate Open
Background High variability in prostate MRI quality might reduce accuracy in prostate cancer detection. Purpose To prospectively evaluate the quality of MRI scanners taking part in the quality control phase of the global PRIME (Prostate Im…
View article: Active surveillance should not be routinely considered in ISUP grade group 2 prostate cancer
Active surveillance should not be routinely considered in ISUP grade group 2 prostate cancer Open
View article: The Highest Grade Group Does Not Drive the Risk of Recurrence when Systematic and Multiparametric Magnetic Resonance Imaging (MRI)-targeted Biopsies are Discordant: Preliminary Findings Using Radical Prostatectomy Pathology as a Surrogate for MRI-targeted Biopsy Grade
The Highest Grade Group Does Not Drive the Risk of Recurrence when Systematic and Multiparametric Magnetic Resonance Imaging (MRI)-targeted Biopsies are Discordant: Preliminary Findings Using Radical Prostatectomy Pathology as a Surrogate for MRI-targeted Biopsy Grade Open
View article: Implementation of 4Kscore as a Secondary Test Before Prostate Biopsy: Impact on US Population Trends for Prostate Cancer
Implementation of 4Kscore as a Secondary Test Before Prostate Biopsy: Impact on US Population Trends for Prostate Cancer Open
We estimate that use of a test called 4Kscore to predict the probability that a patient has high-grade prostate cancer has significantly reduced the number of unnecessary biopsies and overdiagnosis of low-grade cancer in the USA. These dec…
View article: Impact of prostate imaging quality (PI-QUAL) score on the detection of clinically significant prostate cancer at biopsy
Impact of prostate imaging quality (PI-QUAL) score on the detection of clinically significant prostate cancer at biopsy Open
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Contents Open
View article: Long-term oncologic outcomes of robot-assisted radical cystectomy: update series from a high-volume robotic center beyond 10 years of follow-up
Long-term oncologic outcomes of robot-assisted radical cystectomy: update series from a high-volume robotic center beyond 10 years of follow-up Open
View article: Are Urologists Ready for Interpretation of Multiparametric MRI Findings? A Prospective Multicentric Evaluation
Are Urologists Ready for Interpretation of Multiparametric MRI Findings? A Prospective Multicentric Evaluation Open
Aim: To assess urologists’ proficiency in the interpretation of multiparametric magnetic resonance imaging (mpMRI). Materials and Methods: Twelve mpMRIs were shown to 73 urologists from seven Italian institutions. Responders were asked to …
View article: Prostate-specific Antigen Density Cutoff of 0.15 ng/ml/cc to Propose Prostate Biopsies to Patients with Negative Magnetic Resonance Imaging: Efficient Threshold or Legacy of the Past?
Prostate-specific Antigen Density Cutoff of 0.15 ng/ml/cc to Propose Prostate Biopsies to Patients with Negative Magnetic Resonance Imaging: Efficient Threshold or Legacy of the Past? Open
View article: Impact of Early Dorsal Venous Complex Ligation on Urinary Continence Recovery after Robot-assisted Radical Prostatectomy: Results from a Phase 3 Randomized Controlled Trial
Impact of Early Dorsal Venous Complex Ligation on Urinary Continence Recovery after Robot-assisted Radical Prostatectomy: Results from a Phase 3 Randomized Controlled Trial Open
View article: Should we combine systematic with MRI-targeted biopsy? Implications for the management of patients with prostate cancer
Should we combine systematic with MRI-targeted biopsy? Implications for the management of patients with prostate cancer Open
View article: Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score
Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score Open
In this multinational study, we developed a scoring system incorporating clinical and magnetic resonance imaging characteristics to predict which patients have prostate cancer requiring treatment and which patients can safely forego an inv…
View article: Combining PSA and PET features to select candidates for salvage lymph node dissection in recurrent prostate cancer
Combining PSA and PET features to select candidates for salvage lymph node dissection in recurrent prostate cancer Open
Objective To evaluate the relationship between pre‐operative PSA value, 68 Ga‐prostate‐specific‐membrane‐antigen (PSMA) PET performance and oncologic outcomes after salvage lymph node dissection (sLND) for biochemical recurrent prostate ca…
View article: Prostate-specific membrane antigen Radioguided Surgery to Detect Nodal Metastases in Primary Prostate Cancer Patients Undergoing Robot-assisted Radical Prostatectomy and Extended Pelvic Lymph Node Dissection: Results of a Planned Interim Analysis of a Prospective Phase 2 Study
Prostate-specific membrane antigen Radioguided Surgery to Detect Nodal Metastases in Primary Prostate Cancer Patients Undergoing Robot-assisted Radical Prostatectomy and Extended Pelvic Lymph Node Dissection: Results of a Planned Interim Analysis of a Prospective Phase 2 Study Open
View article: Focal therapy for prostate cancer: what is really needed to move from investigational to valid therapeutic alternative?—a narrative review
Focal therapy for prostate cancer: what is really needed to move from investigational to valid therapeutic alternative?—a narrative review Open
By targeting the three aforementioned weaknesses of FT, greater adoption is expected, finally making FT a valid therapeutic alternative, potentially reshaping prostate cancer treatment and functional outcomes.
View article: The Mount Sinai Prebiopsy Risk Calculator for Predicting any Prostate Cancer and Clinically Significant Prostate Cancer: Development of a Risk Predictive Tool and Validation with Advanced Neural Networking, Prostate Magnetic Resonance Imaging Outcome Database, and European Randomized Study of Screening for Prostate Cancer Risk Calculator
The Mount Sinai Prebiopsy Risk Calculator for Predicting any Prostate Cancer and Clinically Significant Prostate Cancer: Development of a Risk Predictive Tool and Validation with Advanced Neural Networking, Prostate Magnetic Resonance Imaging Outcome Database, and European Randomized Study of Screening for Prostate Cancer Risk Calculator Open
We developed the Mount Sinai Prebiopsy Risk Calculator (MSP-RC) to assess the likelihood of any prostate cancer and clinically significant disease based on a combination of clinical and imaging characteristics. MSP-RC is applicable to all …
View article: Grade and stage misclassification in intermediate unfavorable‐risk prostate cancer radiotherapy candidates
Grade and stage misclassification in intermediate unfavorable‐risk prostate cancer radiotherapy candidates Open
Background We tested for upgrading (Gleason grade group [GGG] ≥ 4) and/or upstaging to non‐organ‐confined stage ([NOC] ≥ pT3/pN1) in intermediate unfavorable‐risk (IU) prostate cancer (PCa) patients treated with radical prostatectomy, sinc…
View article: Available evidence on HIFU for focal treatment of prostate cancer: a systematic review
Available evidence on HIFU for focal treatment of prostate cancer: a systematic review Open
This review highlights that focal HIFU therapy appears to be a safe procedure, while short-term cancer control rate is encouraging. Though, second-line treatment or active surveillance seems to be necessary in a significant number of patie…
View article: Re: Dries Develtere, Giuseppe Rosiello, Pietro Piazza, et al. Early Catheter Removal on Postoperative Day 2 After Robot-assisted Radical Prostatectomy: Updated Real-life Experience with the Aalst Technique. Eur Urol Focus. In press. https://doi.org/10.1016/j.euf.2021.10.003
Re: Dries Develtere, Giuseppe Rosiello, Pietro Piazza, et al. Early Catheter Removal on Postoperative Day 2 After Robot-assisted Radical Prostatectomy: Updated Real-life Experience with the Aalst Technique. Eur Urol Focus. In press. https://doi.org/10.1016/j.euf.2021.10.003 Open