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View article: Long‐term risk and predictors of high‐risk human papillomavirus persistence after thermal ablation amongst women living with <scp>HIV</scp> in West Africa
Long‐term risk and predictors of high‐risk human papillomavirus persistence after thermal ablation amongst women living with <span>HIV</span> in West Africa Open
Introduction Mounting evidence supports the use of thermal ablation in women positively screened with high‐risk Human Papillomaviruses ( hrHPV ) but limited data are available on the long‐term post‐treatment outcomes in women living with H…
View article: Molecular epidemiology of tuberculosis in Western Burkina Faso: insights from a MIRU-VNTR study
Molecular epidemiology of tuberculosis in Western Burkina Faso: insights from a MIRU-VNTR study Open
This study provides new insights into the genetic diversity and transmission dynamics of MTBC strains in Burkina Faso. While the observed low clustering suggests limited recent TB transmission, the findings require further validation throu…
View article: Molecular Epidemiology of Tuberculosis in Western Burkina Faso: Insights from a MIRU-VNTR Study
Molecular Epidemiology of Tuberculosis in Western Burkina Faso: Insights from a MIRU-VNTR Study Open
Introduction : Tuberculosis (TB) remains a significant public health challenge in Burkina Faso, with limited molecular epidemiology data available to track strain diversity and transmission patterns. This study aims to characterize the gen…
View article: Socio-Demographic Characteristics of Newly Diagnosed People Living with HIV Initiating Antiretroviral Treatment at the Adult Day Hospital of Bobo-Dioulasso Over a Five-year Period
Socio-Demographic Characteristics of Newly Diagnosed People Living with HIV Initiating Antiretroviral Treatment at the Adult Day Hospital of Bobo-Dioulasso Over a Five-year Period Open
Background: HIV infection is a major public health problem in sub-Saharan Africa, particularly in Burkina Faso. This study aimed to describe the socio-demographic characteristics of newly person living with HIV initiating antiretroviral tr…
View article: Impact of switching to a dolutegravir‐based regimen on body weight changes: insights from West African adult HIV cohorts
Impact of switching to a dolutegravir‐based regimen on body weight changes: insights from West African adult HIV cohorts Open
Introduction Adverse metabolic effects related to dolutegravir (DTG) are increasingly reported as countries are adopting DTG‐based regimens as first‐line antiretroviral therapy (ART), but there is limited data from sub‐Saharan Africa. We e…
View article: Performance of visual inspection, partial genotyping, and their combination for the triage of women living with HIV who are screen positive for human papillomavirus: Results from the AIMA‐CC ANRS 12375 multicentric screening study
Performance of visual inspection, partial genotyping, and their combination for the triage of women living with HIV who are screen positive for human papillomavirus: Results from the AIMA‐CC ANRS 12375 multicentric screening study Open
The WHO recommends the use of human papillomavirus (HPV) testing for primary cervical cancer (CC) screening because of its high sensitivity. However, triage is desirable to correctly identify HPV+ women who have high‐grade lesions (CIN2+) …
View article: Genetic diversity of enteric viruses responsible of gastroenteritis in urban and rural Burkina Faso
Genetic diversity of enteric viruses responsible of gastroenteritis in urban and rural Burkina Faso Open
Background Viral gastrointestinal infections remain a major public health concern in developing countries. In Burkina Faso, there are very limited updated data on the circulating viruses and their genetic diversity. Objectives This study i…
View article: Implementation of a Clinical Decision Support System for Antimicrobial Prescribing in Sub-Saharan Africa: Multisectoral Qualitative Study
Implementation of a Clinical Decision Support System for Antimicrobial Prescribing in Sub-Saharan Africa: Multisectoral Qualitative Study Open
Background Suboptimal use of antimicrobials is a driver of antimicrobial resistance in West Africa. Clinical decision support systems (CDSSs) can facilitate access to updated and reliable recommendations. Objective This study aimed to asse…
View article: Knowledge and practices of hand hygiene among healthcare workers in three urban hospitals in Bobo-Dioulasso city, 2022 (Burkina Faso)
Knowledge and practices of hand hygiene among healthcare workers in three urban hospitals in Bobo-Dioulasso city, 2022 (Burkina Faso) Open
Background The hands of healthcare workers are the major source of healthcare-associated infection transmission. Hand hygiene (HH) remains the most effective measure for preventing such infections. This study aimed to assess knowledge, tec…
View article: Efficacy and safety of three antiretroviral therapy regimens for treatment-naive African adults living with HIV-2 (FIT-2): a pilot, phase 2, non-comparative, open-label, randomised controlled trial
Efficacy and safety of three antiretroviral therapy regimens for treatment-naive African adults living with HIV-2 (FIT-2): a pilot, phase 2, non-comparative, open-label, randomised controlled trial Open
View article: Sex-Based Disparities in the Transition to Dolutegravir-Based Antiretroviral Therapy in West African HIV Cohorts
Sex-Based Disparities in the Transition to Dolutegravir-Based Antiretroviral Therapy in West African HIV Cohorts Open
Transition to dolutegravir among 21 167 individuals experienced in antiretroviral therapy in West Africa showed heterogeneous timelines and patterns. Initially reported sex disparities tended to catch up over time with persisting dispariti…
View article: Effects of the COVID-19 Pandemic on ART Initiation and Access to HIV Viral Load Monitoring in Adults Living With HIV in West Africa: A Regression Discontinuity Analysis
Effects of the COVID-19 Pandemic on ART Initiation and Access to HIV Viral Load Monitoring in Adults Living With HIV in West Africa: A Regression Discontinuity Analysis Open
Objectives: Efforts to control the COVID-19 pandemic have potentially compromised the availability and/or quality of HIV services. We aimed to assess the pandemic's impact on antiretroviral therapy (ART) initiation and HIV viral load (VL) …
View article: Using adult care visits to diagnose HIV infection in children, Burkina Faso
Using adult care visits to diagnose HIV infection in children, Burkina Faso Open
Testing HIV-exposed children through their mothers in outpatient clinics is feasible and effective in a low HIV-prevalence setting such as Burkina Faso. Implementation of this strategy to detect undiagnosed HIV-infected children is recomme…
View article: Reported antibiotic use among patients in the multicenter ANDEMIA infectious diseases surveillance study in sub-saharan Africa
Reported antibiotic use among patients in the multicenter ANDEMIA infectious diseases surveillance study in sub-saharan Africa Open
View article: Availability of substance use screening and treatment within HIV clinical sites across seven geographic regions within the IeDEA consortium
Availability of substance use screening and treatment within HIV clinical sites across seven geographic regions within the IeDEA consortium Open
View article: The Tuberculosis Sentinel Research Network (TB-SRN) of the International epidemiology Databases to Evaluate AIDS (IeDEA): protocol for a prospective cohort study in Africa, Southeast Asia and Latin America
The Tuberculosis Sentinel Research Network (TB-SRN) of the International epidemiology Databases to Evaluate AIDS (IeDEA): protocol for a prospective cohort study in Africa, Southeast Asia and Latin America Open
Introduction Tuberculosis (TB) is a leading infectious cause of death globally. It is the most common opportunistic infection in people living with HIV, and the most common cause of their morbidity and mortality. Following TB treatment, su…
View article: Characterization of extended-spectrum beta-lactamase and carbapenemase genes in bacteria from environment in Burkina Faso
Characterization of extended-spectrum beta-lactamase and carbapenemase genes in bacteria from environment in Burkina Faso Open
Introduction: This study aimed to characterize extended-spectrum beta-lactamase (ESBL) and carbapenemase genes in bacteria from the environment in Bobo-Dioulasso, Burkina Faso. Methodology: This study was conducted from January 18 to Decem…
View article: Preexposure prophylaxis availability among health facilities participating in the global International epidemiology Databases to Evaluate AIDS (IeDEA) consortium
Preexposure prophylaxis availability among health facilities participating in the global International epidemiology Databases to Evaluate AIDS (IeDEA) consortium Open
Background: While recognized as a key HIV prevention strategy, preexposure prophylaxis (PrEP) availability and accessibility are not well documented globally. We aimed to describe PrEP drug registration status and the availability of PrEP …
View article: A Qualitative Study of the Experience of COVID-19 Patients in Burkina Faso
A Qualitative Study of the Experience of COVID-19 Patients in Burkina Faso Open
In Burkina Faso, the health system is characterized by systemic insufficient and antiquated health-care infrastructures. Consequently, few health-care establishments have the required resources to diagnose and manage patients with COVID-19…
View article: The burden of the coronavirus disease 2019 virus infection in Burkina Faso: Results from a World Health Organization UNITY population‐based, age‐stratified sero‐epidemiological investigation
The burden of the coronavirus disease 2019 virus infection in Burkina Faso: Results from a World Health Organization UNITY population‐based, age‐stratified sero‐epidemiological investigation Open
Background This study aimed to estimate the anti‐SARS‐CoV‐2 antibody seroprevalence in the general population of Bobo‐Dioulasso and Ouagadougou (Burkina Faso). Methods We collected from March to April 2021 blood samples from randomly selec…
View article: Automated blood culture systems for isolation of bacterial pathogens of bloodstream infection: The experience of Bobo-Dioulasso Teaching Hospital, Burkina Faso
Automated blood culture systems for isolation of bacterial pathogens of bloodstream infection: The experience of Bobo-Dioulasso Teaching Hospital, Burkina Faso Open
Background: Identification of the causative agent is an essential requirement for better treatment of bloodstream infection. The BacT/Alert 3D (BioMérieux, Marcy l’Étoile, France), is a blood culture system equipped with CO2 sensors to mon…
View article: Analytical performances of the Xpert MTB/RIF assay using stool specimens to improve the diagnosis of pulmonary tuberculosis in Burkina Faso, a tuberculosis endemic country
Analytical performances of the Xpert MTB/RIF assay using stool specimens to improve the diagnosis of pulmonary tuberculosis in Burkina Faso, a tuberculosis endemic country Open
Timely diagnosis of Pulmonary Tuberculosis (PTB) is associated with good prognosis, but remains difficult in primary healthcare facilities and particularly in children and patients living with HIV. The aim of this study was to compare the …
View article: Acceptability and feasibility of home and hospital follow-up in Burkina Faso and Guinea: A mixed-method study among patients of the COVID-19 Coverage-Africa clinical trial
Acceptability and feasibility of home and hospital follow-up in Burkina Faso and Guinea: A mixed-method study among patients of the COVID-19 Coverage-Africa clinical trial Open
Patient experiences and perspectives on trial participation and follow-up may influence their compliance with research procedures or negatively impact their well-being. We aimed to explore the acceptability and feasibility of home-based an…
View article: Seroprevalence of SARS-CoV-2 IgG and associated factors among people living with HIV over the first 12 months following the outbreak of COVID-19 in Burkina Faso, a sub-Saharan African country
Seroprevalence of SARS-CoV-2 IgG and associated factors among people living with HIV over the first 12 months following the outbreak of COVID-19 in Burkina Faso, a sub-Saharan African country Open
Objective This study aimed to evaluate the seroprevalence of anti-SARS-CoV-2 IgG and factors associated with the infection among PLWHIV over the first 12 months following the outbreak of COVID-19 in Burkina Faso. Design A retrospective cro…
View article: Incidence rate and predictors of COVID-19 in the two largest cities of Burkina Faso - prospective cohort study in 2021 (ANRS-COV13)
Incidence rate and predictors of COVID-19 in the two largest cities of Burkina Faso - prospective cohort study in 2021 (ANRS-COV13) Open
View article: Evaluation of the impact of COVID-19 in people coinfected with HIV and/or tuberculosis in low-income countries: study protocol for mixed methods research in Burkina Faso
Evaluation of the impact of COVID-19 in people coinfected with HIV and/or tuberculosis in low-income countries: study protocol for mixed methods research in Burkina Faso Open
Background An issue of particular concern is the impact of the 2019 novel coronavirus (2019 nCOV) on the people coinfected with the Human Immuno-deficiency Virus (HIV) and/or tuberculosis (TB). Unfortunately, this interaction has not been …
View article: Efficacy and Safety of Three Antiretroviral Therapy Regimens in Treatment-Naive African Adults Infected with HIV-2: A Randomised Controlled Phase II Trial
Efficacy and Safety of Three Antiretroviral Therapy Regimens in Treatment-Naive African Adults Infected with HIV-2: A Randomised Controlled Phase II Trial Open
View article: Can the Urine Dipstick Test Be an Alternative in the Screening of Urinary Tract Infections for Inpatients in the Context of a Low-Income Country?
Can the Urine Dipstick Test Be an Alternative in the Screening of Urinary Tract Infections for Inpatients in the Context of a Low-Income Country? Open
Background: Urinary Tract Infection (UTI), a prevalent bacterial infection in adults, heavily relies on cytobacteriological examination of urine (CBEU) for diagnosis. However, in resource-limited countries, accessibility to CBEU remains hi…
View article: Long-term evolution of immunological and virological parameters in patients undergoing treatments for HIV-1 infection at the Day Hospital of Bobo-Dioulasso, Burkina Faso
Long-term evolution of immunological and virological parameters in patients undergoing treatments for HIV-1 infection at the Day Hospital of Bobo-Dioulasso, Burkina Faso Open
this study highlighted the different trends of viral load and LTCD4 evolution over 10 years of antiretroviral treatment. It showed a good immunovirological response was shown at the beginning of antiretroviral therapy, and then, a poor evo…
View article: Perceptions of COVID-19 among communities of Conakry (Guinea): a qualitative study exploring the context of the ANRS COV33 Coverage-Africa therapeutic trial
Perceptions of COVID-19 among communities of Conakry (Guinea): a qualitative study exploring the context of the ANRS COV33 Coverage-Africa therapeutic trial Open
Objectives To explore communities’ perceptions about COVID-19 in the context of the ANRS COV33 Coverage-Africa clinical trial evaluating the efficacy of treatments in preventing clinical worsening of COVID-19. Design Descriptive qualitativ…