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View article: Predictors of Treatment Failure, Second-Line Therapy Outcomes, and Patient Satisfaction after Prostatic Artery Embolization: A Retrospective Study in Benign Prostatic Hyperplasia
Predictors of Treatment Failure, Second-Line Therapy Outcomes, and Patient Satisfaction after Prostatic Artery Embolization: A Retrospective Study in Benign Prostatic Hyperplasia Open
Introduction: This study aims to evaluate the effectiveness of prostatic artery embolization (PAE) in treating benign prostatic hyperplasia (BPH), focusing on identifying the predictors of treatment failure and assessing patient satisfacti…
View article: Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin
Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin Open
Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify …
View article: Preoperative semen quality is superior to the quality shortly after orchiectomy in patients with testicular germ cell tumour – a retrospective study from two centres in Germany
Preoperative semen quality is superior to the quality shortly after orchiectomy in patients with testicular germ cell tumour – a retrospective study from two centres in Germany Open
Background Sperm cryopreservation in patients with testicular germ cell tumours (GCTs) is traditionally performed after orchiectomy. But, some evidence suggests preoperative semen quality to be superior. We aimed to clarify the optimal tim…
View article: Biomarker microRNA-371a-3p - expression in malignancies other than germ-cell tumours
Biomarker microRNA-371a-3p - expression in malignancies other than germ-cell tumours Open
View article: Andrologie
Andrologie Open
View article: Patient-reported outcomes after one-stage neourethral reconstruction in transmen with phalloplasty-associated strictures and fistulas
Patient-reported outcomes after one-stage neourethral reconstruction in transmen with phalloplasty-associated strictures and fistulas Open
Introduction Urethral strictures and fistulas arising after gender-affirming surgery in transmen require meticulous management strategies. This study evaluates the safety and efficacy of urethral reconstruction and patient satisfaction pos…
View article: Serum Levels of MicroRNA-371a-3p for Predicting the Histology of Postchemotherapy Residual Masses of Germ Cell Tumours
Serum Levels of MicroRNA-371a-3p for Predicting the Histology of Postchemotherapy Residual Masses of Germ Cell Tumours Open
The microRNA-371a-3p (M371) test can identify about two-thirds of patients with viable cancer in residual metastatic masses following chemotherapy for germ cell tumours. Only masses with high percentages of viable cancer cells can be ident…
View article: TRACK_9: Testosterone replacement assessment: Classical vs. functional hypogonadism‐knowledge from a 9‐year study
TRACK_9: Testosterone replacement assessment: Classical vs. functional hypogonadism‐knowledge from a 9‐year study Open
Background and objective The longitudinal efficacy and clinical utility of Testosterone Therapy (TTh) in ameliorating functional hypogonadism (FH) remain contentious, with long‐term data being scarce. To address this lacuna, a comprehensiv…
View article: Advancing Intraoperative Assessment of Urethral Stricture Anatomic Variation: A Prospective Proof-of-Concept Study
Advancing Intraoperative Assessment of Urethral Stricture Anatomic Variation: A Prospective Proof-of-Concept Study Open
Introduction: Urethral strictures, particularly those refractory to endoscopic interventions, are commonly treated through open urethroplasty. However, predicting recurrence in homogeneous patient populations remains challeng…
View article: What do patients with Peyronie's disease expect from therapy? A prospective multi‐center study
What do patients with Peyronie's disease expect from therapy? A prospective multi‐center study Open
Background Little is known about patients’ pre‐treatment expectations in Peyronie's disease (PD). Objective To evaluate in detail patients’ expectations of conservative therapy and surgery. Patients and methods This multi‐center study pros…
View article: Exploring the Relationship between (De-)Centralized Health Care Delivery, Client-Centeredness, and Health Outcomes—Results of a Retrospective, Single-Center Study of Transgender People Undergoing Vaginoplasty
Exploring the Relationship between (De-)Centralized Health Care Delivery, Client-Centeredness, and Health Outcomes—Results of a Retrospective, Single-Center Study of Transgender People Undergoing Vaginoplasty Open
Introduction: Transgender health care interventions (e.g., gender-affirming surgery) support transgender and gender-diverse people to transition to their gender and are delivered in both centralized (by one interdisciplinary institution) a…
View article: Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue
Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue Open
Human prepubertal testicular tissues are rare, but organ culture conditions to develop a system for human in vitro-spermatogenesis are an essential option for fertility preservation in prepubertal boys subjected to gonadotoxic therapy. To …
View article: ‘Case of the Month’ from University Medical Center Hamburg‐Eppendorf, Germany: vulvar cancer after female–male gender reassignment
‘Case of the Month’ from University Medical Center Hamburg‐Eppendorf, Germany: vulvar cancer after female–male gender reassignment Open
While the true prevalence of gender dysphoria ranges between 0.5% and 1.3%, it has been reported that the amount of gender-affirming surgery is growing at high rates of up to 155% per annum [1, 2]. Gender dysphoria has been associated with…
View article: Large-scale analyses of the X chromosome in 2,354 infertile men discover recurrently affected genes associated with spermatogenic failure
Large-scale analyses of the X chromosome in 2,354 infertile men discover recurrently affected genes associated with spermatogenic failure Open
View article: Penile Flap Inversion Vaginoplasty in Transgender Women: Contemporary Morbidity and Learning-Curve Analysis From a High-Volume Reconstructive Center
Penile Flap Inversion Vaginoplasty in Transgender Women: Contemporary Morbidity and Learning-Curve Analysis From a High-Volume Reconstructive Center Open
Objectives Numbers of PIV are rising. The aim of this study is to analyze the surgical learning-curve (LC) on the grounds of perioperative complications. Patients and Methods 108 PIVs, performed by a single surgeon between 2015 and 2018 ha…
View article: Oncologic impact of concomitant prostate cancer characteristics at the time of radical cystoprostatectomy for bladder cancer: a population-based analysis
Oncologic impact of concomitant prostate cancer characteristics at the time of radical cystoprostatectomy for bladder cancer: a population-based analysis Open
Objective: The aim of this study was to evaluate the prognostic impact of concomitant prostate cancer (PCa) of the cancer-specific mortality (CSM) in the aging patient’s papulation with bladder cancer (BCa) treated with radical cystoprosta…
View article: Early testicular maturation is sensitive to depletion of spermatogonial pool in sickle cell disease
Early testicular maturation is sensitive to depletion of spermatogonial pool in sickle cell disease Open
ATS indicates acute thorax syndrome; FI: feritlity index; S/T: spermatogonia per round tubular cross-section; Hb: hemoglobin; HbF: fetal hemoglobin; HbS: sickle hemoglobin; HU: hydroxyurea; y: year; x d: per day; LDH: lactate dehydrogenase…
View article: Squamous cell carcinoma of the renal pelvis in a patient with long-term spinal cord injury—a case report
Squamous cell carcinoma of the renal pelvis in a patient with long-term spinal cord injury—a case report Open
View article: ESSM Position Statement on Surgical Treatment of Peyronie's Disease
ESSM Position Statement on Surgical Treatment of Peyronie's Disease Open
Introduction Patients with Peyronie's disease may experience significat distress. The choice of treatment depends on a variety of factors, including the stage of the disease, the presence of pain, severity and direction of the curvature, p…
View article: Exploring the intersection of functional recurrence, patient-reported sexual function, and treatment satisfaction after anterior buccal mucosal graft urethroplasty
Exploring the intersection of functional recurrence, patient-reported sexual function, and treatment satisfaction after anterior buccal mucosal graft urethroplasty Open
View article: Continence and Complication Rates of Artificial Urinary Sphincter Devices (AMS 800) for Parkinson and Stroke Patients with Incontinence after Prostate Surgery: Retrospective Analysis of a Prospective Database
Continence and Complication Rates of Artificial Urinary Sphincter Devices (AMS 800) for Parkinson and Stroke Patients with Incontinence after Prostate Surgery: Retrospective Analysis of a Prospective Database Open
Objectives: The artificial urinary sphincter (AUS) is the gold standard treatment for severe stress urinary incontinence (SUI). According to the literature, patients suffering from Parkinson’s disease (PD) or stroke (ST) show adverse conti…
View article: Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy
Copy number variations in primary tumor, serum and lymph node metastasis of bladder cancer patients treated with radical cystectomy Open
The aim of the present study was to analyze copy number variations (CNV) of multiple oncogenes and tumor suppressor genes in genomic DNA from primary tumor tissue, lymph node metastasis and cell-free DNA (cfDNA) from serum of 72 urothelial…
View article: Learning benefits of live surgery and semi-live surgery in urology—informing the debate with results from the International Meeting of Reconstructive Urology (IMORU) VIII
Learning benefits of live surgery and semi-live surgery in urology—informing the debate with results from the International Meeting of Reconstructive Urology (IMORU) VIII Open
View article: The Impact of Circulating Tumor Cells on Venous Thromboembolism and Cardiovascular Events in Bladder Cancer Patients Treated with Radical Cystectomy
The Impact of Circulating Tumor Cells on Venous Thromboembolism and Cardiovascular Events in Bladder Cancer Patients Treated with Radical Cystectomy Open
Background: Cancer is a relevant risk factor for venous thromboembolism (VTE). Circulating tumor cells (CTC) are associated with an increased risk of VTE in breast cancer. In addition, circulating cell-free nucleic acids have been associat…
View article: Retrograde ejaculation after holmium laser enucleation of the prostate (HoLEP)—Impact on sexual function and evaluation of patient bother using validated questionnaires
Retrograde ejaculation after holmium laser enucleation of the prostate (HoLEP)—Impact on sexual function and evaluation of patient bother using validated questionnaires Open
Background A vast body of literature has focused on erectile function after Holmium Laser Enucleation of the Prostate (HoLEP). Interestingly, retrograde ejaculation (RE), despite its frequency has sparsely been investigated. Objectives To …
View article: Perioperative morbidity after ureterocutaneostomy, conduit, and continent urinary diversion following radical cystectomy: A comparative assessment using the Comprehensive Complication Index® and the updated EAU guidelines of standardized reporting
Perioperative morbidity after ureterocutaneostomy, conduit, and continent urinary diversion following radical cystectomy: A comparative assessment using the Comprehensive Complication Index® and the updated EAU guidelines of standardized reporting Open
View article: Does 5-alpha reductase inhibitor intake impact procedural efficacy, short- and long-term functional outcomes in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP)? A retrospective single-center analysis among 1,360 patients
Does 5-alpha reductase inhibitor intake impact procedural efficacy, short- and long-term functional outcomes in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP)? A retrospective single-center analysis among 1,360 patients Open
View article: Prospective evaluation of genomic aberrations of circulating, cell-free DNA, primary tumor and lymph node metastasis in bladder cancer patients treated with radical cystectomy
Prospective evaluation of genomic aberrations of circulating, cell-free DNA, primary tumor and lymph node metastasis in bladder cancer patients treated with radical cystectomy Open
View article: Does anaesthetic technique (spinal block vs. general anesthesia) impact procedural efficacy and functional outcomes in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP)? A retrospective single-center analysis among 1,159 patients
Does anaesthetic technique (spinal block vs. general anesthesia) impact procedural efficacy and functional outcomes in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP)? A retrospective single-center analysis among 1,159 patients Open
View article: The impact of pain and postoperative complications on outcome in patients treated with buccal mucosa graft urethroplasty – results of a randomized controlled study
The impact of pain and postoperative complications on outcome in patients treated with buccal mucosa graft urethroplasty – results of a randomized controlled study Open