Arnaud Augert
YOU?
Author Swipe
View article: MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues
MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues Open
The MYC transcription factor requires MAX for DNA binding and widespread activation of gene expression in both normal and neoplastic cells. Inactivating mutations in MAX are associated with a subset of neuroendocrine cancers including pheo…
View article: MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues
MAX inactivation deregulates the MYC network and induces neuroendocrine neoplasia in multiple tissues Open
The MYC transcription factor requires MAX for DNA binding and widespread activation of gene expression in both normal and neoplastic cells. Surprisingly, inactivating mutations in MAX are associated with a subset of neuroendocrine cancers …
View article: Data from PTEN Is a Potent Suppressor of Small Cell Lung Cancer
Data from PTEN Is a Potent Suppressor of Small Cell Lung Cancer Open
Small cell lung carcinoma (SCLC) is a highly metastatic tumor type with neuroendocrine features and a dismal prognosis. PTEN mutations and PIK3CA activating mutations have been reported in SCLC but the functional relevance of this pathway …
View article: Figures S1-S16 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition
Figures S1-S16 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition Open
Supplementary Figures S1 to S16
View article: Supplementary Figures 1 - 4 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer
Supplementary Figures 1 - 4 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer Open
PDF file - 1172KB, S1. Neuroendocrine lung tumors in Rb/p53 AdCre model. S2. Neuroendocrine lung tumors in Rb/p53/Ptenlox/+AdCre model. S3. Analyses of Rb, p53 and Pten recombination in lung tumors. S4. Comparison of Rb/p53/Ptenlox/+ vs. R…
View article: Data from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition
Data from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition Open
CREBBP, encoding an acetyltransferase, is among the most frequently mutated genes in small cell lung cancer (SCLC), a deadly neuroendocrine tumor type. We report acceleration of SCLC upon Crebbp inactivation in an autochthonous mouse model…
View article: Figures S1-S16 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition
Figures S1-S16 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition Open
Supplementary Figures S1 to S16
View article: Data from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition
Data from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition Open
CREBBP, encoding an acetyltransferase, is among the most frequently mutated genes in small cell lung cancer (SCLC), a deadly neuroendocrine tumor type. We report acceleration of SCLC upon Crebbp inactivation in an autochthonous mouse model…
View article: Tables S1-S5 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition
Tables S1-S5 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition Open
Supplementary tables S1 to S5
View article: Supplementary Tables 1 - 2 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer
Supplementary Tables 1 - 2 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer Open
XLSX file - 38KB, Supplemental Table 1. Primer sequences used for Real Time PCR Supplemental Table 2. Coverage of mouse exome samples.
View article: Tables S1-S5 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition
Tables S1-S5 from <i>Crebbp</i> Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition Open
Supplementary tables S1 to S5
View article: Data from PTEN Is a Potent Suppressor of Small Cell Lung Cancer
Data from PTEN Is a Potent Suppressor of Small Cell Lung Cancer Open
Small cell lung carcinoma (SCLC) is a highly metastatic tumor type with neuroendocrine features and a dismal prognosis. PTEN mutations and PIK3CA activating mutations have been reported in SCLC but the functional relevance of this pathway …
View article: Supplementary Tables 1 - 2 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer
Supplementary Tables 1 - 2 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer Open
XLSX file - 38KB, Supplemental Table 1. Primer sequences used for Real Time PCR Supplemental Table 2. Coverage of mouse exome samples.
View article: Supplementary Figures 1 - 4 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer
Supplementary Figures 1 - 4 from PTEN Is a Potent Suppressor of Small Cell Lung Cancer Open
PDF file - 1172KB, S1. Neuroendocrine lung tumors in Rb/p53 AdCre model. S2. Neuroendocrine lung tumors in Rb/p53/Ptenlox/+AdCre model. S3. Analyses of Rb, p53 and Pten recombination in lung tumors. S4. Comparison of Rb/p53/Ptenlox/+ vs. R…
View article: Supplementary Figure 6 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 6 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 83KB, PKA activation favors escape from OIS hallmarks.
View article: Supplementary Materials and Methods from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Materials and Methods from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 100KB, Supplementary Materials and Methods
View article: Supplementary Figure 3 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 3 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 151KB, KCNA1 knockdown and KCNA1 mutant S446E promote OIS escape.
View article: Supplementary Figure 7 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 7 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 1285KB, PKA activation favors OIS escape.
View article: Supplementary Figure 3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
Supplementary Figure 3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence Open
Supplementary Figure 3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
View article: Supplementary Figure 2 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 2 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 923KB, KCNA1 impacts RAF-induced hallmarks of OIS.
View article: Supplementary Figure 2 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 2 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 923KB, KCNA1 impacts RAF-induced hallmarks of OIS.
View article: Supplementary Figure 3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
Supplementary Figure 3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence Open
Supplementary Figure 3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
View article: Supplementary Figure Legends 1-3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
Supplementary Figure Legends 1-3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence Open
Supplementary Figure Legends 1-3 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
View article: Supplementary Figure 3 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 3 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 151KB, KCNA1 knockdown and KCNA1 mutant S446E promote OIS escape.
View article: Supplementary Figure 5 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 5 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 5961KB, KCNA1 localization is regulated by PKA.
View article: Supplementary Figure 1 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
Supplementary Figure 1 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence Open
Supplementary Figure 1 from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
View article: Supplementary Figure 8 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 8 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 2383KB, PKA activation reverses the transformation blockage induced by KCNA1.
View article: Supplementary Figure 7 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Supplementary Figure 7 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation Open
PDF - 1285KB, PKA activation favors OIS escape.
View article: Data from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence
Data from A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence Open
Normal cell growth can be permanently blocked when cells enter a state known as senescence. This phenomenon can be triggered by various stresses, such as replicative exhaustion, oncogenic stimulation, or oxidative stress. Senescence preven…