Arnaud Gacouin
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View article: Factors associated with ICU mortality and long-term outcomes in immunocompromised patients admitted to the intensive care unit for acute respiratory failure
Factors associated with ICU mortality and long-term outcomes in immunocompromised patients admitted to the intensive care unit for acute respiratory failure Open
View article: Correction: Transplant-free survival in acute liver failure patients receiving MARS®, plasma exchange or no liver support. A real-life 21-year retrospective cohort study in a referral center
Correction: Transplant-free survival in acute liver failure patients receiving MARS®, plasma exchange or no liver support. A real-life 21-year retrospective cohort study in a referral center Open
View article: Transplant-free survival in acute liver failure patients receiving MARS®, plasma exchange or no liver support. A real-life 21-year retrospective cohort study in a referral center
Transplant-free survival in acute liver failure patients receiving MARS®, plasma exchange or no liver support. A real-life 21-year retrospective cohort study in a referral center Open
Background Whether Molecular Adsorbent Recirculating System (MARS) dialysis and high-volume plasma exchange (HVPE) may improve survival in acute liver failure (ALF) remains unclear. A referral center retrospective cohort study was conducte…
View article: Predictive value of chest tomography at early stage in moderate to severe ARDS
Predictive value of chest tomography at early stage in moderate to severe ARDS Open
Background: Computed tomography (CT) is widely used in the early stages of acute respiratory distress syndrome (ARDS) for diagnose and patient management. Recent ARDS guidelines have questioned the utility of identifying ARDS subphenotype …
View article: Hypnosis for unplanned procedural pain in the intensive care unit: the HYPIC randomized clinical trial
Hypnosis for unplanned procedural pain in the intensive care unit: the HYPIC randomized clinical trial Open
View article: A Bundle of Interventions to Prevent Pressure Ulcers During Prone Position in Adult Patients With Acute Respiratory Distress Syndrome: Results of a French Stepped‐Wedge Randomized Controlled Trial
A Bundle of Interventions to Prevent Pressure Ulcers During Prone Position in Adult Patients With Acute Respiratory Distress Syndrome: Results of a French Stepped‐Wedge Randomized Controlled Trial Open
Background In patients with moderate‐to‐severe acute respiratory distress syndrome, the frequency of pressure ulcers is higher in the prone position than in the supine position. Aim To assess the effect of a bundle of interventions to prev…
View article: Are presentations of thoracic CT performed on admission to the ICU associated with mortality at day-90 in COVID-19 related ARDS?
Are presentations of thoracic CT performed on admission to the ICU associated with mortality at day-90 in COVID-19 related ARDS? Open
In patients with moderate to severe COVID-19 ARDS, systematic CT assessment of lung parenchymal injury was not a reliable predictor of 90-day mortality or ICU-related complications.
View article: Prognosis of critically ill immunocompromised patients with COVID-19 admitted for acute respiratory failure: a retrospective propensity score analysis
Prognosis of critically ill immunocompromised patients with COVID-19 admitted for acute respiratory failure: a retrospective propensity score analysis Open
After adjustment for prognostic variables, the immunocompromised status of patients admitted to the ICU for SARS-CoV-2-related ARF was not associated with increased mortality, despite a significantly longer ICU stay and a greater rate of I…
View article: Association of obesity on short- and long-term survival in patients with moderate to severe pneumonia-related ARDS: a retrospective cohort study
Association of obesity on short- and long-term survival in patients with moderate to severe pneumonia-related ARDS: a retrospective cohort study Open
View article: Anti-factor Xa during unfractionated heparin therapy in critically ill patients: Development of prediction models using machine learning
Anti-factor Xa during unfractionated heparin therapy in critically ill patients: Development of prediction models using machine learning Open
Objective Unfractionated heparin (UFH) is a widely used therapy in intensive care units (ICUs) and is associated with an increased risk of serious adverse events or death if the therapeutic target is not reached quickly. Adjusting UFH dosa…
View article: Effects of Antifungal Treatment in COVID-19-Associated Pulmonary Aspergillosis: A European Multicenter Cohort Study
Effects of Antifungal Treatment in COVID-19-Associated Pulmonary Aspergillosis: A European Multicenter Cohort Study Open
View article: Admission chest CT scan of intensive care patients with interstitial lung disease: Unveiling its limited predictive value through visual and automated analyses in a retrospective study (ILDICTO)
Admission chest CT scan of intensive care patients with interstitial lung disease: Unveiling its limited predictive value through visual and automated analyses in a retrospective study (ILDICTO) Open
Our study showed that the extent of radiological findings and the severity of fibrosis indices on admission chest CT scans of ILD patients admitted to the ICU for ARF were not associated with subsequent deterioration.
View article: Effect of high-flow nasal cannula oxygen versus standard oxygen on mortality in patients with acute hypoxaemic respiratory failure: protocol for a multicentre, randomised controlled trial (SOHO)
Effect of high-flow nasal cannula oxygen versus standard oxygen on mortality in patients with acute hypoxaemic respiratory failure: protocol for a multicentre, randomised controlled trial (SOHO) Open
Introduction First-line oxygenation strategy in patients with acute hypoxaemic respiratory failure consists in standard oxygen or high-flow nasal oxygen therapy. Clinical practice guidelines suggest the use of high-flow nasal oxygen rather…
View article: Factors associated with cancer treatment resumption after ICU stay in patients with solid tumors
Factors associated with cancer treatment resumption after ICU stay in patients with solid tumors Open
View article: Impact of cardiovascular risk factors and cardiac diseases on mortality in patients with moderate to severe ARDS: A retrospective cohort study
Impact of cardiovascular risk factors and cardiac diseases on mortality in patients with moderate to severe ARDS: A retrospective cohort study Open
History of CAD and/or AF and/or VR was associated with mortality in ARDS. Prompt referral to cardiologists for comprehensive management post-ICU discharge may be warranted to optimize outcomes in this vulnerable population.
View article: Development and validation of a community acquired sepsis-worsening score in the adult emergency department: a prospective cohort: the CASC score
Development and validation of a community acquired sepsis-worsening score in the adult emergency department: a prospective cohort: the CASC score Open
View article: Development and validation of a community acquired sepsis-worsening score in the adult emergency department: a prospective cohort. The CASC score
Development and validation of a community acquired sepsis-worsening score in the adult emergency department: a prospective cohort. The CASC score Open
Background Sepsis is a leading cause of death and serious illness that requires early recognition and therapeutic management to improve survival. The quick-SOFA score helps in its recognition, but its diagnostic performance is insufficient…
View article: Sex difference in the risk of extubation failure in ICUs
Sex difference in the risk of extubation failure in ICUs Open
View article: Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS
Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS Open
Importance Prone positioning may improve outcomes in patients with severe acute respiratory distress syndrome (ARDS), but it is unknown whether prone positioning improves clinical outcomes among patients with ARDS who are undergoing venove…
View article: Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial
Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial Open
View article: Early discontinuation of combination antibiotic therapy in severe community-acquired pneumonia: a retrospective cohort study
Early discontinuation of combination antibiotic therapy in severe community-acquired pneumonia: a retrospective cohort study Open
View article: Impact of Arterial CO<sub>2</sub> Retention in Patients With Moderate or Severe ARDS
Impact of Arterial CO<sub>2</sub> Retention in Patients With Moderate or Severe ARDS Open
Severe hypercapnia was associated with mortality in subjects with ARDS who received lung-protective ventilation. Our results deserve further evaluation of the strategies and treatments that aim to control CO2 retention.
View article: Moderate-to-severe ARDS: COVID-19 patients compared to influenza patients for ventilator parameters and mortality
Moderate-to-severe ARDS: COVID-19 patients compared to influenza patients for ventilator parameters and mortality Open
Background This study aimed to compare ventilatory parameters recorded in the first days of acute respiratory distress syndrome (ARDS) and mortality at day 60 between coronavirus disease 2019 (COVID-19) and influenza ARDS patients with art…
View article: Continued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial
Continued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial Open
View article: Legionella Pneumophila Serogroup 1 Serum LPS Detection as a Biomarker for Legionnaires’ Disease Prognosis: A Multicentre Prospective Cohort Study
Legionella Pneumophila Serogroup 1 Serum LPS Detection as a Biomarker for Legionnaires’ Disease Prognosis: A Multicentre Prospective Cohort Study Open
View article: Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece
Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece Open
Among patients who had a high risk of extubation failure, spontaneous-breathing trials performed with PSV did not result in significantly more ventilator-free days at day 28 than spontaneous-breathing trials performed with a T-piece. (Supp…
View article: Effect of High-Flow Nasal Cannula Oxygen vs Standard Oxygen Therapy on Mortality in Patients With Respiratory Failure Due to COVID-19
Effect of High-Flow Nasal Cannula Oxygen vs Standard Oxygen Therapy on Mortality in Patients With Respiratory Failure Due to COVID-19 Open
Importance The benefit of high-flow nasal cannula oxygen (high-flow oxygen) in terms of intubation and mortality in patients with respiratory failure due to COVID-19 is controversial. Objective To determine whether the use of high-flow oxy…
View article: Acquired agitation in acute respiratory distress syndrome with COVID-19 compared to influenza patients: a propensity score matching observational study
Acquired agitation in acute respiratory distress syndrome with COVID-19 compared to influenza patients: a propensity score matching observational study Open
View article: Fiberoptic endoscopic validation of a clinical screening test of swallowing function in critically ill patients performed within 24 h after extubation
Fiberoptic endoscopic validation of a clinical screening test of swallowing function in critically ill patients performed within 24 h after extubation Open
View article: Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest
Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest Open
ClinicalTrials.gov Identifier: NCT02876458.