Aapo L. Aro
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View article: Cost Differences Between Oral Anticoagulation Therapies in Patients with Atrial Fibrillation in Finland
Cost Differences Between Oral Anticoagulation Therapies in Patients with Atrial Fibrillation in Finland Open
EUPAS29845.
View article: Oral anticoagulation in patients with gastrointestinal bleeding and new‐onset atrial fibrillation: A population‐based registry‐linkage study
Oral anticoagulation in patients with gastrointestinal bleeding and new‐onset atrial fibrillation: A population‐based registry‐linkage study Open
Background Limited data exist on the prevalence of gastrointestinal bleeding (GIB) in patients with new‐onset atrial fibrillation (AF) and the impact of GIB on the initiation of oral anticoagulation (OAC) therapy. Methods A population‐base…
View article: Arrhythmia care in ESC member countries: the 2025 ESC-EHRA atlas on heart rhythm disorders
Arrhythmia care in ESC member countries: the 2025 ESC-EHRA atlas on heart rhythm disorders Open
The ESC-EHRA Atlas on Heart Rhythm Disorders was developed to comprehensively map arrhythmia care across the European Society of Cardiology (ESC) member countries. A survey of National Cardiac Societies, Working Groups, and other EHRA part…
View article: Factors associated with oral anticoagulant non-use at first ischemic stroke in atrial fibrillation: A nationwide study
Factors associated with oral anticoagulant non-use at first ischemic stroke in atrial fibrillation: A nationwide study Open
Background: Limited data exist on characteristics and patterns associated with patients with atrial fibrillation (AF) who encounter first-ever ischemic stroke (IS) while not on oral anticoagulation (OAC) therapy. Methods: From a nationwide…
View article: Hemorrhagic Stroke in Atrial Fibrillation: Trends in Incidence, Case Fatality, and Prior Oral Anticoagulation
Hemorrhagic Stroke in Atrial Fibrillation: Trends in Incidence, Case Fatality, and Prior Oral Anticoagulation Open
Background Despite increased atrial fibrillation (AF) and oral anticoagulation (OAC) use among patients with intracerebral hemorrhage, trends in hemorrhagic stroke (HS) incidence in AF remain unclear. We examined recent epidemiological tre…
View article: Complications and adverse events after atrial fibrillation catheter ablation procedures: a Nationwide Cohort Study
Complications and adverse events after atrial fibrillation catheter ablation procedures: a Nationwide Cohort Study Open
Background Catheter ablation is a well-established treatment to prevent atrial fibrillation (AF) recurrences and to relieve symptoms. More information is needed on the occurrence of adverse events following the procedure. Purpose We invest…
View article: Reduced dose direct oral anticoagulants and time-in-therapeutic-range defined warfarin in new-onset atrial fibrillation: a report from the nationwide FinACAF study
Reduced dose direct oral anticoagulants and time-in-therapeutic-range defined warfarin in new-onset atrial fibrillation: a report from the nationwide FinACAF study Open
Aims Direct oral anticoagulants (DOACs) at reduced dosage regimens are the first choice of ischaemic stroke (IS) prevention for patients with atrial fibrillation (AF) and elevated bleeding risk or renal insufficiency. We compared the outco…
View article: Adrenal aldosterone synthase (CYP11B2) histopathology and its association with disease-induced sudden death: a cross-sectional study
Adrenal aldosterone synthase (CYP11B2) histopathology and its association with disease-induced sudden death: a cross-sectional study Open
Finnish State Research funds and independent research foundations: Aarne Koskelo Foundation, the Finnish Kidney Foundation, and the Finnish Foundation for Cardiovascular Research.
View article: Physician Preferences in Using Novel Digital Devices for the Management of Atrial Fibrillation—A DAS‐CAM III Survey
Physician Preferences in Using Novel Digital Devices for the Management of Atrial Fibrillation—A DAS‐CAM III Survey Open
Aim A recent European Heart Rhythm Association (EHRA) practical guide provides guidance on the use of novel digital devices for heart rhythm analysis using either electrocardiogram (ECG) or photoplethysmography (PPG) technology for the dia…
View article: Temporal trends of catheter ablation procedures in patients with atrial fibrillation and atrial flutter: A nationwide cohort study
Temporal trends of catheter ablation procedures in patients with atrial fibrillation and atrial flutter: A nationwide cohort study Open
The use of catheter ablation more than doubled during 2012-2018 and the increase was particularly seen in the elderly patients. Nevertheless, only a minority of AF and AFL patients were treated with catheter ablations.
View article: Comorbidities and risk of death in atrial fibrillation: a nationwide cohort study
Comorbidities and risk of death in atrial fibrillation: a nationwide cohort study Open
Background Atrial fibrillation (AF) is associated with increased mortality, cardiovascular morbidity, and risk of stroke. With aging population, the number of AF patients is increasing, and they present with more comorbidities representing…
View article: Sex- and age-specific differences in the use of antiarrhythmic therapies among atrial fibrillation patients: a nationwide cohort study
Sex- and age-specific differences in the use of antiarrhythmic therapies among atrial fibrillation patients: a nationwide cohort study Open
Aims Atrial fibrillation (AF) patients frequently require active rhythm control therapy to maintain sinus rhythm and reduce symptom burden. Our study assessed whether antiarrhythmic therapies (AATs) are used disproportionately between men …
View article: Quo vadis, the leading arrhythmia? Projecting the prevalence of atrial fibrillation up to 2070
Quo vadis, the leading arrhythmia? Projecting the prevalence of atrial fibrillation up to 2070 Open
Introduction The prevalence of atrial fibrillation (AF) is strongly associated with age, and with increasing life expectancy worldwide, the number of AF patients has been steadily rising. However, long-term projections of AF prevalence are…
View article: Single catheter ablation of atrioventricular node in a patient with dextrocardia and permanent atrial fibrillation via peripheral vascular access using remote magnetic navigation: a case report
Single catheter ablation of atrioventricular node in a patient with dextrocardia and permanent atrial fibrillation via peripheral vascular access using remote magnetic navigation: a case report Open
Background Cardiac interventions may be challenging in patients with congenital cardiac abnormalities. This case reports cardiac resynchronisation therapy pacemaker (CRT-P) implantation, and single catheter ablation of atrioventricular (AV…
View article: Temporal trends in mortality and causes of death in patients with incident atrial fibrillation: a nationwide register study from 2010 to 2018
Temporal trends in mortality and causes of death in patients with incident atrial fibrillation: a nationwide register study from 2010 to 2018 Open
Objectives Atrial fibrillation (AF) is associated with increased mortality. Previous studies have reported conflicting results in temporal trends of mortality after AF diagnosis. We aim to address this disparity by investigating the 1-year…
View article: Time-in-therapeutic-range defined warfarin and direct oral anticoagulants in atrial fibrillation: a Nationwide Cohort Study
Time-in-therapeutic-range defined warfarin and direct oral anticoagulants in atrial fibrillation: a Nationwide Cohort Study Open
The outcome was unsatisfactory in the two lowest TTR quartiles - in half of the patients treated with warfarin. The differences between the high TTR groups and standard dose DOACs were absent or modest.
View article: Thromboembolic and bleeding complications after elective cardioversion of atrial fibrillation: a nationwide cohort study
Thromboembolic and bleeding complications after elective cardioversion of atrial fibrillation: a nationwide cohort study Open
Aims Elective cardioversion (ECV) is routinely used in atrial fibrillation (AF) to restore sinus rhythm. However, it includes a risk of thromboembolism even during adequate oral anticoagulation treatment. The aim of this study was to evalu…
View article: Temporal trends of ischemic stroke rates in atrial fibrillation without anticoagulation: a nationwide cohort study from 2007 to 2018
Temporal trends of ischemic stroke rates in atrial fibrillation without anticoagulation: a nationwide cohort study from 2007 to 2018 Open
Background Atrial fibrillation (AF) is a major risk factor for ischemic stroke (IS), but whether the magnitude of this risk has changed over time is unknown. Purpose To evaluate temporal trends in IS rates in patients with AF who have not …
View article: Ischaemic stroke in women with atrial fibrillation: temporal trends and clinical implications
Ischaemic stroke in women with atrial fibrillation: temporal trends and clinical implications Open
Background and Aims Female sex has been linked with higher risk of ischaemic stroke (IS) in atrial fibrillation (AF), but no prior study has examined temporal trends in the IS risk associated with female sex. Methods The registry-linkage F…
View article: Stroke in Patients with Atrial Fibrillation: Epidemiology, Screening, and Prognosis
Stroke in Patients with Atrial Fibrillation: Epidemiology, Screening, and Prognosis Open
Atrial fibrillation (AF) is the most common sustained arrythmia and one of the strongest risk factors and causal mechanisms of ischemic stroke (IS). Acute IS due to AF tends to be more severe than with other etiology of IS and patients wit…
View article: Ischemic Stroke Temporally Associated With New-Onset Atrial Fibrillation: A Population-Based Registry-Linkage Study
Ischemic Stroke Temporally Associated With New-Onset Atrial Fibrillation: A Population-Based Registry-Linkage Study Open
BACKGROUND: Limited data exist on the temporal relationship between new-onset atrial fibrillation (AF) and ischemic stroke and its impact on patients’ clinical characteristics and mortality. METHODS: A population-based registry-linkage dat…
View article: Lower dose direct oral anticoagulation and warfarin in atrial fibrillation. Ischemic stroke, intracranial hemorrhage and mortality in a nationwide registry study
Lower dose direct oral anticoagulation and warfarin in atrial fibrillation. Ischemic stroke, intracranial hemorrhage and mortality in a nationwide registry study Open
Background and aims Direct oral anticoagulants (DOACs) have replaced Vitamin-K antagonists as the primary choice of oral anticoagulation (OAC) in atrial fibrillation (AF). However, after several years of experience with DOACs, no studies h…