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A critical role of the Erk1/2 downstream targets c-Fos, Egr-1, and Egr-2 in PU.1-driven monocyte development Open

Hamid Bashir, G C Binod, Arshad Rahman, Fan Dong · 2025

The Ets family transcription factor PU.1 plays multiple roles in hematopoiesis. PU.1 acts in a graded manner to regulate myeloid and lymphoid development with high expression levels promoting monopoiesis and low expression levels instructi…

Occludin Is Essential to Maintain Normal Alveolar Barrier Integrity and Its Protective Role During ARDS Progression Open

Xin Lin, Haiqing Bai, Michael Barravecchia, Rosemary Norman, Gillian M. Schiralli Lester , et al. · 2024

Biology Medicine

Acute respiratory distress syndrome (ARDS) is a severe lung condition without targeted therapy that is characterized by the disruption of epithelial and endothelial barriers. The role of the tight junction protein occludin in the pathogene…

Bovine Pericardium Scaffold as a Critical Tool for Cardiac Surgery with Mesenchymal Stem Cell Seeding : A Narrative Review Open

Heroe Soebroto, Ferdiansyah Mahyudin, Gondo Mastutik, Ahmad Fiko Nugraha, Arshad Rahman , et al. · 2024

Medicine Biology

This review explores the significance of pericardial dissection in cardiac surgery for managing congenital heart disease (CHD). The procedure often results in intrapericardial adhesion formation, impacting outcomes and increasing hospitali…

Impact of Peptide Sequence on Functional siRNA Delivery and Gene Knockdown with Cyclic Amphipathic Peptide Delivery Agents Open

Melissa L. Jagrosse, Uday Baliga, Christopher W. Jones, J. Russell, C. Garcia , et al. · 2023

Chemistry Biology

Short-interfering RNA (siRNA) oligonucleotide therapeutics that modify gene expression by accessing RNA-interference (RNAi) pathways have great promise for the treatment of a range of disorders; however, their application in clinical setti…

Supplementary Methods from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine

Supplementary Methods from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 1 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Biology Medicine

Supplementary Figure 1 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 9 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine

Supplementary Figure 9 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 1 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Figure 1 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figures 2-5 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Figures 2-5 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure Legends 1-10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Art Biology Medicine

Supplementary Figure Legends 1-10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 6 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Figure 6 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 8 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine

Supplementary Figure 8 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure Legends 1-10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Art Biology Economics

Supplementary Figure Legends 1-10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Data from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Angiogenesis is a critical step during cancer progression. The VEGF is a major stimulator for angiogenesis and is predominantly contributed by cancer cells in tumors. Inhibition of the VEGF signaling pathway has shown promising therapeutic…

Supplementary Figure 9 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Biology Medicine Economics

Supplementary Figure 9 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Data from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Angiogenesis is a critical step during cancer progression. The VEGF is a major stimulator for angiogenesis and is predominantly contributed by cancer cells in tumors. Inhibition of the VEGF signaling pathway has shown promising therapeutic…

Supplementary Figure 10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Figure 10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine

Supplementary Figure 10 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figures 2-5 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Figures 2-5 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 8 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine

Supplementary Figure 8 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 6 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Figure 6 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 7 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Art Medicine Economics

Supplementary Figure 7 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Figure 7 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Figure 7 from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Supplementary Methods from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression Open

Liquan Yang, Guangchun Chen, Sonali Mohanty, Glynis Scott, Fabeha Fazal , et al. · 2023

Medicine Economics

Supplementary Methods from GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression

Therapeutic Targeting of NF-κB in Acute Lung Injury: A Double-Edged Sword Open

Michelle Warren Millar, Fabeha Fazal, Arshad Rahman · 2022

Medicine

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating disease that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most recently, COVID-19. Although our understanding of the mec…

Essential Role of Rho-Associated Kinase in ABO Immune Complex-Mediated Endothelial Barrier Disruption Open

Hannah L. McRae, Michelle Warren Millar, Spencer Slavin, Neil Blumberg, Arshad Rahman , et al. · 2021

Chemistry Biology Medicine

ABO immune complexes (ABO-IC) formed by ABO-incompatible antigen-antibody interaction are associated with hemolysis and platelet destruction in patients transfused with ABO-nonidentical blood products. However, the effects of ABO-IC on end…

Phosphodiesterase 10A Is a Key Mediator of Lung Inflammation Open

Chia George Hsu, Fabeha Fazal, Arshad Rahman, Bradford C. Berk, Yan Chen · 2021

Medicine Biology

Cyclic nucleotides cAMP and cGMP are important regulators of immune cell functions. Phosphodiesterases (PDEs) hydrolyze cAMP and/or cGMP and, thus, play crucial roles in cyclic nucleotide homeostasis. Abnormal alterations of PDE expression…

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