Arthur Nedder
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View article: Systemically injected oxygen within rapidly dissolving microbubbles improves the outcomes of severe hypoxaemia in swine
Systemically injected oxygen within rapidly dissolving microbubbles improves the outcomes of severe hypoxaemia in swine Open
View article: Absorption of an engineered medium‐chain fatty acid analogue in two short bowel syndrome minipig models
Absorption of an engineered medium‐chain fatty acid analogue in two short bowel syndrome minipig models Open
Background Enteral drug therapy is challenging in short bowel syndrome with intestinal failure (SBS‐IF) because of unpredictable absorption. SEFA‐6179 is an enterally administered medium‐chain fatty acid analogue under development for inte…
View article: A Medium-Chain Fatty Acid Analogue Prevents Intestinal Failure–Associated Liver Disease in Preterm Yorkshire Piglets
A Medium-Chain Fatty Acid Analogue Prevents Intestinal Failure–Associated Liver Disease in Preterm Yorkshire Piglets Open
View article: A Digestive Cartridge Reduces Parenteral Nutrition Dependence and Increases Bowel Growth in a Piglet Short Bowel Model
A Digestive Cartridge Reduces Parenteral Nutrition Dependence and Increases Bowel Growth in a Piglet Short Bowel Model Open
Objective: To determine whether the use of an immobilized lipase cartridge (ILC) to hydrolyze fats in enteral nutrition (EN) reduces parenteral nutrition (PN) dependence in a porcine model of short bowel syndrome with intestinal failure (S…
View article: An in-line digestive cartridge increases enteral fat and vitamin absorption in a porcine model of short bowel syndrome
An in-line digestive cartridge increases enteral fat and vitamin absorption in a porcine model of short bowel syndrome Open
ALC-078 increases the absorption of fat-soluble vitamins and may improve fat malabsorption. Future studies should determine whether ALC-078 can reduce PN dependence and if these findings translate to human patients with SBS.
View article: Outcomes and Perioperative Nutritional Management in a Porcine Model of Short Bowel Syndrome
Outcomes and Perioperative Nutritional Management in a Porcine Model of Short Bowel Syndrome Open
View article: Biochemical and Hematologic Reference Intervals for Anesthetized, Female, Juvenile Yorkshire Swine
Biochemical and Hematologic Reference Intervals for Anesthetized, Female, Juvenile Yorkshire Swine Open
Swine are widely used in biomedical research, translational research, xenotransplantation, and agriculture. For these uses, physiologic reference intervals are extremely important for assessing the health status of the swine and diagnosing…
View article: Early Enteral Administration of a Complex Lipid Emulsion Supplement Prevents Postnatal Deficits in Docosahexaenoic and Arachidonic Acids and Increases Tissue Accretion of Lipophilic Nutrients in Preterm Piglets
Early Enteral Administration of a Complex Lipid Emulsion Supplement Prevents Postnatal Deficits in Docosahexaenoic and Arachidonic Acids and Increases Tissue Accretion of Lipophilic Nutrients in Preterm Piglets Open
Background Preterm delivery and current nutrition strategies result in deficiencies of critical long‐chain fatty acids (FAs) and lipophilic nutrients, increasing the risk of preterm morbidities. We sought to determine the efficacy of preve…
View article: Perioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine
Perioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine Open
This study used a swine model of mildly hypothermic prolonged circulatory arrest and found that the addition of 2.4% inhaled hydrogen gas to inspiratory gases during and after the ischemic insult significantly decreased neurologic and rena…
View article: Technique and perioperative management of left pneumonectomy in neonatal piglets
Technique and perioperative management of left pneumonectomy in neonatal piglets Open