Arun Jeyabalan
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View article: Remote blood sampling differential protein expression associated with persistent hypertension following a hypertensive disorder of pregnancy
Remote blood sampling differential protein expression associated with persistent hypertension following a hypertensive disorder of pregnancy Open
Objective Hypertensive disorders of pregnancy are associated with future cardiovascular risk, however, the underlying mechanisms are unclear. We sought to test the feasibility of postpartum remote blood sampling following a hypertensive di…
View article: Cardio-obstetrics in the Cardiac Intensive Care Unit: An Introductory Guide
Cardio-obstetrics in the Cardiac Intensive Care Unit: An Introductory Guide Open
The care of the cardio-obstetric population in the cardiac intensive care unit is challenging due to limited data in this patient population. Optimal care requires a broad multidisciplinary team of experts such that both maternal and fetal…
View article: Safety of Agitated Saline Contrast Use During Transthoracic Echocardiography in Pregnancy
Safety of Agitated Saline Contrast Use During Transthoracic Echocardiography in Pregnancy Open
View article: Establishing a Remote Blood Pressure Monitoring Program Through the First Year Postpartum After Pregnancy-Induced Hypertension
Establishing a Remote Blood Pressure Monitoring Program Through the First Year Postpartum After Pregnancy-Induced Hypertension Open
View article: Blood Pressure Trajectories Through the First Year Postpartum in Overweight or Obese Individuals Following a Hypertensive Disorder of Pregnancy
Blood Pressure Trajectories Through the First Year Postpartum in Overweight or Obese Individuals Following a Hypertensive Disorder of Pregnancy Open
BACKGROUND: Hypertensive disorders of pregnancy are associated with cardiovascular disease; however, patterns of blood pressure (BP) recovery are understudied. We compared pregnancy and postpartum BP trajectories among individuals with hyp…
View article: Peripartum Lipid Apheresis
Peripartum Lipid Apheresis Open
View article: Blood pressure trajectories through the first year postpartum following a hypertensive disorder of pregnancy
Blood pressure trajectories through the first year postpartum following a hypertensive disorder of pregnancy Open
Background Hypertensive disorders of pregnancy (HDP) are associated with future cardiovascular disease, predominantly through development of chronic hypertension, however the patterns of blood pressure recovery following a HDP are understu…
View article: Maternal and Neonatal Outcomes of Pregnancy within 7 years after Roux-Y Gastric Bypass or Sleeve Gastrectomy Surgery
Maternal and Neonatal Outcomes of Pregnancy within 7 years after Roux-Y Gastric Bypass or Sleeve Gastrectomy Surgery Open
View article: A Case Series of Parturients With Mechanical Mitral Valves
A Case Series of Parturients With Mechanical Mitral Valves Open
More women with mechanical mitral valves (MMVs) are pursuing pregnancy. Guidelines exist for pregnancy anticoagulation, but they do not address individualized anticoagulation during delivery-a period of risk for bleeding, thrombosis, and a…
View article: A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy
A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy Open
Background While preeclampsia (PE) is a leading cause of pregnancy-related morbidity/mortality, its underlying mechanisms are not fully understood. DNA methylation (DNAm) is a dynamic regulator of gene expression that may offer insight int…
View article: Postpartum home blood pressure monitoring and lifestyle intervention in overweight and obese individuals the first year after gestational hypertension or pre‐eclampsia: A pilot feasibility trial
Postpartum home blood pressure monitoring and lifestyle intervention in overweight and obese individuals the first year after gestational hypertension or pre‐eclampsia: A pilot feasibility trial Open
Objective To test the feasibility of a randomised trial of home blood pressure monitoring paired with a remote lifestyle intervention (Heart Health 4 New Moms) versus home blood pressure monitoring alone versus control in individuals with …
View article: Feasibility of Utilizing Telehealth in a Multidisciplinary Postpartum Hypertension Clinic
Feasibility of Utilizing Telehealth in a Multidisciplinary Postpartum Hypertension Clinic Open
Implementation of a multidisciplinary postpartum hypertension clinic in the virtual space is feasible, targets women at high risk for persistently elevated postpartum BP, and maintains equal attendance compared with in-person visits. Virtu…
View article: Postpartum home blood pressure monitoring and lifestyle intervention in the first year after a hypertensive disorder of pregnancy: A pilot feasibility trial
Postpartum home blood pressure monitoring and lifestyle intervention in the first year after a hypertensive disorder of pregnancy: A pilot feasibility trial Open
Objective: To test the feasibility of a randomized trial of home blood pressure monitoring paired with a remote lifestyle intervention vs. home blood pressure monitoring alone vs. control in individuals with a hypertensive disorder of preg…
View article: Implementation of a universal postpartum blood pressure monitoring program: feasibility and outcomes
Implementation of a universal postpartum blood pressure monitoring program: feasibility and outcomes Open
View article: An exploratory study of white blood cell proportions across preeclamptic and normotensive pregnancy by self-identified race in individuals with overweight or obesity
An exploratory study of white blood cell proportions across preeclamptic and normotensive pregnancy by self-identified race in individuals with overweight or obesity Open
Objective: Examine white blood cell (WBC) proportions across preeclamptic (n = 28 cases) and normotensive (n = 28 controls) pregnancy in individuals with overweight/obesity.Methods: WBC proportions were inferred from genome-w…
View article: Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy
Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy Open
View article: An Exploratory Study of Epigenetic Age in Preeclamptic and Normotensive Pregnancy Reveals Differences by Self-Reported Race but Not Pregnancy Outcome
An Exploratory Study of Epigenetic Age in Preeclamptic and Normotensive Pregnancy Reveals Differences by Self-Reported Race but Not Pregnancy Outcome Open
View article: Objectively Measured Sedentary Behavior and Physical Activity Across 3 Trimesters of Pregnancy: The Monitoring Movement and Health Study
Objectively Measured Sedentary Behavior and Physical Activity Across 3 Trimesters of Pregnancy: The Monitoring Movement and Health Study Open
Background : Though moderate- to vigorous-intensity physical activity is recommended, limited research exists on sedentary behavior (SED) during pregnancy. Methods : The authors conducted a prospective cohort study to describe objectively …
View article: Sedentary behaviour and physical activity across pregnancy and birth outcomes
Sedentary behaviour and physical activity across pregnancy and birth outcomes Open
Background Shorter gestation or smaller birth size are indicators of a suboptimal fetal environment and negatively impact short‐ and long‐term offspring health. Understanding how modifiable maternal behaviours, such as moderate‐to‐vigorous…
View article: Racial Differences in DNA Methylation-Based Age Acceleration in Preeclamptic and Normotensive Pregnancy
Racial Differences in DNA Methylation-Based Age Acceleration in Preeclamptic and Normotensive Pregnancy Open
Background Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality. Chronological age and race are associated with increased risk of preeclampsia; however, the pathophysiology of preeclampsia and how these risk fac…
View article: Black Women Have Evidence of Cardiometabolic Risk and Damage to the Microvascular Glycocalyx 1 to 10 Years After Uncomplicated Pregnancy.
Black Women Have Evidence of Cardiometabolic Risk and Damage to the Microvascular Glycocalyx 1 to 10 Years After Uncomplicated Pregnancy. Open
View article: Utilization of Epigenome-wide DNA Methylation for Longitudinal Comparison of White Blood Cell Proportions Across Preeclamptic and Normotensive Pregnancy by Self-Reported Race
Utilization of Epigenome-wide DNA Methylation for Longitudinal Comparison of White Blood Cell Proportions Across Preeclamptic and Normotensive Pregnancy by Self-Reported Race Open
Objective We utilized epigenome-wide DNA methylation data to estimate/compare white blood cell (WBC) proportions in plasma across preeclamptic (case) and uncomplicated, normotensive (control) pregnancy. Methods We previously collected meth…
View article: Circulating pregnancy hormone relaxin as a first trimester biomarker for preeclampsia
Circulating pregnancy hormone relaxin as a first trimester biomarker for preeclampsia Open
Relaxin shows little improvement in the performance of first trimester prediction models, which does not support its clinical implementation as a biomarker. Although this study was only correlational, the results point to a possible pathop…
View article: DNA Methylation of Endoglin Pathway Genes in Pregnant Women With and Without Preeclampsia
DNA Methylation of Endoglin Pathway Genes in Pregnant Women With and Without Preeclampsia Open
Objective: We compared blood-based DNA methylation levels of endoglin ( ENG) and transforming growth factor beta receptor 2 ( TGFβR2) gene promoter regions between women with clinically-overt preeclampsia and women with uncomplicated, norm…
View article: Primary Presentation of Pulmonary Hypertension in the Peripartum
Primary Presentation of Pulmonary Hypertension in the Peripartum Open
View article: Clinical Course, Associated Factors, and Blood Pressure Profile of Delayed-Onset Postpartum Preeclampsia
Clinical Course, Associated Factors, and Blood Pressure Profile of Delayed-Onset Postpartum Preeclampsia Open
OBJECTIVE: To identify clinical risk factors associated with development of delayed-onset postpartum preeclampsia, and to characterize management and subsequent risk of cardiovascular disease. METHODS: This is a case–control study of women…
View article: Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy
Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy Open
View article: Relationship of Postpartum Levels of Cystatin and High-Sensitivity C-Reactive Protein and Duration of Lactation in Mothers with Previous Gestational Hypertension or Preeclampsia
Relationship of Postpartum Levels of Cystatin and High-Sensitivity C-Reactive Protein and Duration of Lactation in Mothers with Previous Gestational Hypertension or Preeclampsia Open
Background: Women with hypertensive disorders of pregnancy are at increased risk of cardiovascular disease in later life. We sought to determine the association between lactation and markers of maternal cardiovascular health …
View article: Research Recommendations From the National Institutes of Health Workshop on Predicting, Preventing, and Treating Preeclampsia
Research Recommendations From the National Institutes of Health Workshop on Predicting, Preventing, and Treating Preeclampsia Open
View article: 14: Extracellular vesicle proteomic markers obtained at 12 weeks predict spontaneous preterm birth less than 35 weeks gestation: a validation with specific characterization of marker behavior by fetal gender and parity
14: Extracellular vesicle proteomic markers obtained at 12 weeks predict spontaneous preterm birth less than 35 weeks gestation: a validation with specific characterization of marker behavior by fetal gender and parity Open