Arvind Sonwane
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View article: Correlation between diarrhoea associated SNPs and pre-weaning growth rate in Landlly piglets
Correlation between diarrhoea associated SNPs and pre-weaning growth rate in Landlly piglets Open
The present study was aimed to investigate the relationship between diarrhoea-associated polymorphisms and pre-weaning growth rates in an organized Landlly herd. A total of 250 piglets were genotyped for 10 shortlisted SNPs and assessed fo…
View article: Development and characterization of new muscle line from Lates cacarifer (Bloch, 1790) towards cultivated seafood research
Development and characterization of new muscle line from Lates cacarifer (Bloch, 1790) towards cultivated seafood research Open
Lates calcarifer (Asian Seabass) is one of the important aquaculture species, widely cultured in the Indo-Pacific region. It is a euryhaline and catadromous fish found in near estuaries. A cell line was developed from muscle tissue of Asia…
View article: Identification of Gin-α Hyperactivated Recombinase-based RNA-Guided Recombinase Platform Target Sites in the Zebrafish Genome
Identification of Gin-α Hyperactivated Recombinase-based RNA-Guided Recombinase Platform Target Sites in the Zebrafish Genome Open
Background: RNA-guided recombinase (RGR) platform is recombinase action-based genome engineering platform. It is a fusion of dead Cas9 (dCas9) and evolved recombinase with relaxed target specificity. RGR is facile, programmable and has hig…
View article: Genetic improvement and genomic resources of important cyprinid species: status and future perspectives for sustainable production
Genetic improvement and genomic resources of important cyprinid species: status and future perspectives for sustainable production Open
Cyprinid species are the most cultured aquatic species around the world in terms of quantity and total value. They account for 25% of global aquaculture production and significantly contribute to fulfilling the demand for fish food. The aq…
View article: Single-Nucleotide Polymorphism (SNP) array: an array of hope for genetic improvement of aquatic species and fisheries management
Single-Nucleotide Polymorphism (SNP) array: an array of hope for genetic improvement of aquatic species and fisheries management Open
In recent years, significant progress in genomic technologies has revolutionized the field of aquaculture. These advancements have facilitated the utilization of DNA markers, particularly single nucleotide polymorphisms (SNPs), to enhance …
View article: Muscle transcriptome sequencing revealed thermal stress responsive regulatory genes in farmed rohu, Labeo rohita (Hamilton, 1822)
Muscle transcriptome sequencing revealed thermal stress responsive regulatory genes in farmed rohu, Labeo rohita (Hamilton, 1822) Open
Rohu, Labeo rohita is one of the most important aquaculture species in the Indian subcontinent. The physiological responses to thermal stress or climate change at the molecular level are less understood in rohu. In the present work, transc…
View article: Bovine Genome Analysis to Unravel the Location and Feature of Target Sites of RNA-Guided Hyperactivated Recombinase Gin with Spacer Length Six
Bovine Genome Analysis to Unravel the Location and Feature of Target Sites of RNA-Guided Hyperactivated Recombinase Gin with Spacer Length Six Open
Background: Programmable nucleases are very promising tools of genome editing (GE), but they suffer from limitations including potential risk of genotoxicity which led to the exploration of safer approach of GE based on RNA-guided recombin…
View article: Modulation of granulosa cell function via CRISPR-Cas fuelled editing of BMPR-IB gene in goats (Capra hircus)
Modulation of granulosa cell function via CRISPR-Cas fuelled editing of BMPR-IB gene in goats (Capra hircus) Open
BMPs are multifunctional growth factors implicated in regulating the ovarian function as key intra-ovarian factors. Biological effects of BMPs are mediated through binding with membrane bound receptors like BMPR-IB and initiating downstrea…
View article: PCR- RFLP Polymorphism at Exon 3 and Promoter Region of Prolactin Gene in Gaolao Cattle
PCR- RFLP Polymorphism at Exon 3 and Promoter Region of Prolactin Gene in Gaolao Cattle Open
The present study was planned to investigate significant polymorphism in exon3 and promoter regions of prolactin gene in Gaolao cattle and its association (if any) with milk components. A total of 50 randomly selected Gaolao cows were geno…
View article: Exploration of RNA-Guided Recombinase Target Sites for Hyperactivated Recombinase Beta in Bovine Genome
Exploration of RNA-Guided Recombinase Target Sites for Hyperactivated Recombinase Beta in Bovine Genome Open
The present study was conducted to determine the effect of different cooling systems; Fan Fogger (FF) and Fan Pad (FP) on micro environment of poultry house, thermal comfort, welfare, egg production and egg quality parameters of laying hen…
View article: Transcriptional Regulation of Thrombospondins and Its Functional Validation through CRISPR/Cas9 Mediated Gene Editing in Corpus Luteum of Water Buffalo (Bubalus Bubalis)
Transcriptional Regulation of Thrombospondins and Its Functional Validation through CRISPR/Cas9 Mediated Gene Editing in Corpus Luteum of Water Buffalo (Bubalus Bubalis) Open
Collectively, these data provide evidence that thrombospondins along with their receptors are expressed at varying levels in different stages of CL progression with maximum expression during the late and regressing stages. These results ar…
View article: Association of single nucleotide polymorphisms in IFNGR1 and IFNGR2 genes with bovine tuberculosis
Association of single nucleotide polymorphisms in IFNGR1 and IFNGR2 genes with bovine tuberculosis Open
Interferon Gamma Receptor (IFNGR) genes play an important role in the immune response against mycobacteria by regulating the proinflammatory cytokine Interferon Gamma (IFNG) alongwith subsequent mycobactericidal milieu and are potential st…
View article: Candidate Gene Polymorphism vis-a-vis Immune Response to Important Infectious Diseases in Bovines
Candidate Gene Polymorphism vis-a-vis Immune Response to Important Infectious Diseases in Bovines Open
Infectious diseases have major adverse effects on livestock production, both in terms of economics and on animal welfare. 10-25 % loss in milk production efficiency has been reported in tuberculosis infected animals. Udder infections alone…
View article: Red flour beetle (Tribolium castaneum): From population genetics to functional genomics
Red flour beetle (Tribolium castaneum): From population genetics to functional genomics Open
Tribolium castaneum is a small and low maintenance beetle that has emerged as a most suitable insect model for studying developmental biology and functional genetic analysis. Diverse population genetic studies have been conducted using Tri…
View article: Association of SNP markers in immune response genes with resistance or susceptibility to Mycobacteriun avium paratuberculosis in Cattle
Association of SNP markers in immune response genes with resistance or susceptibility to Mycobacteriun avium paratuberculosis in Cattle Open
Background: Bovine paratuberculosis, also known as Johne's disease (JD), is a chronic, granulomatous inflammatory disease of the intestines of ruminants and some wild-type species caused by Mycobacterium avium spp. paratuberculosis (MAP). …
View article: Quantification and comparison of TLR2 activity in monocyte-derived macrophages of zebu and crossbred cattle.
Quantification and comparison of TLR2 activity in monocyte-derived macrophages of zebu and crossbred cattle. Open
The present study was conducted to quantify and compare TLR2 (toll-like receptor 2) activity in monocyte-derived macrophages of zebu (Tharparkar) and crossbred (Holstein-Friesian × Jersey × Brown Swiss × Hariana) cattle. The cells were eit…
View article: Association study of Single Nucleotide Polymorphisms (SNP) in Toll-like Receptor 9 gene with bovine tuberculosis
Association study of Single Nucleotide Polymorphisms (SNP) in Toll-like Receptor 9 gene with bovine tuberculosis Open
Toll-like Receptor 9 (TLR9) play an important role in recognition of components of intracellular pathogens like Mycobacterium bovis and subsequent activation of both innate and adaptive immune response and is potential strong candidates fo…
View article: Relative expression of oxytocin receptor gene in buffalo endometrium in late luteal phase and pregnancy stages
Relative expression of oxytocin receptor gene in buffalo endometrium in late luteal phase and pregnancy stages Open
Molecular level information related to buffalo (Bubalus bubalis) reproduction and related genes is not present at appropriate level. If such exploration is made in the form of comparison between expression of genes is made between non-preg…
View article: mRNA Expression of Chemokine Genes in Bovine Tuberculosis Infected Crossbred Cattle
mRNA Expression of Chemokine Genes in Bovine Tuberculosis Infected Crossbred Cattle Open
Host genetic variation in disease resistance is mainly attributable to variability in host immune responses to infection. Analysis of variation in host gene expression following M. bovis exposure and infection in cattle offers scope for a …
View article: Single nucleotide polymorphisms in toll-like receptor genes and case-control association studies with bovine tuberculosis
Single nucleotide polymorphisms in toll-like receptor genes and case-control association studies with bovine tuberculosis Open
These findings indicate the presence of SNPs in TLR2 and TLR4 genes in our resource population. Upon validation in independent, large resource population and following biological characterization, SNP rs55617172 can be incorporated in mark…
View article: Genetic polymorphism and expression analysis of leptin gene in rabbit
Genetic polymorphism and expression analysis of leptin gene in rabbit Open
Leptin plays an important role in the regulation of feed intake, energy metabolism, growth and reproduction of rabbit. We used the polymerase chain reaction- single stranded confirmation polymorphism (PCR-SSCP) technique to screen for DNA …