Arya Mariam Roy
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View article: HISTOPATHOLOGICAL SPECTRUM OF RENAL LESIONS IN POST NEPHRECTOMY SPECIMENS: AN AUDIT IN BURDWAN MEDICAL COLLEGE AND HOSPITAL.
HISTOPATHOLOGICAL SPECTRUM OF RENAL LESIONS IN POST NEPHRECTOMY SPECIMENS: AN AUDIT IN BURDWAN MEDICAL COLLEGE AND HOSPITAL. Open
View article: Clinical Characteristics and Survival Trends of Male Breast Cancer in the United States: A Propensity Score Matched Analysis
Clinical Characteristics and Survival Trends of Male Breast Cancer in the United States: A Propensity Score Matched Analysis Open
Background: Male breast cancer (MBC) is extremely rare, representing less than 1% of breast cancer (BC). Owing to the rarity, there is a substantial knowledge gap regarding the survival trends of MBC compared with female breast cancer (FBC…
View article: Racial disparities in the management of deep vein thrombosis from a nationwide hospitalization study
Racial disparities in the management of deep vein thrombosis from a nationwide hospitalization study Open
View article: Towards a Better Understanding of Mesothelioma: A Comprehensive Review of Diagnosis, Therapy and Biomarkers
Towards a Better Understanding of Mesothelioma: A Comprehensive Review of Diagnosis, Therapy and Biomarkers Open
Malignant pleural mesothelioma (MPM) is a rare but highly aggressive cancer, primarily caused by asbestos exposure, with limited diagnostic and therapeutic options. The disease is characterized by late-stage diagnosis and poor prognosis, n…
View article: Epidemiology, Survival, and Second Primary Malignancies in T‐Cell Large Granular Lymphocytic Leukemia
Epidemiology, Survival, and Second Primary Malignancies in T‐Cell Large Granular Lymphocytic Leukemia Open
Introduction Large granular lymphocytic leukemia (LGL) is a rare lymphoproliferative disorder, with limited literature available about the epidemiology, survival, and development of secondary primary malignancies (SPMs) in T‐LGL. Methods T…
View article: 200P Role of Oncotype DX risk categorization and receipt of chemotherapy on survival outcomes among men with node-positive (pN1) hormone receptor positive (HR+) breast cancer
200P Role of Oncotype DX risk categorization and receipt of chemotherapy on survival outcomes among men with node-positive (pN1) hormone receptor positive (HR+) breast cancer Open
View article: Editorial: Immunotherapy in urologic malignancies
Editorial: Immunotherapy in urologic malignancies Open
View article: Updates on Breast Reconstruction: Surgical Techniques, Challenges, and Future Directions
Updates on Breast Reconstruction: Surgical Techniques, Challenges, and Future Directions Open
The increasing global incidence of breast cancer underscores the significance of breast reconstruction in enhancing patients' quality of life. Breast reconstruction primarily falls into two categories: implant-based techniques and autologo…
View article: DEPTH2 score was associated with cell proliferation and immune cell infiltrations but not with systemic treatment response in breast cancer
DEPTH2 score was associated with cell proliferation and immune cell infiltrations but not with systemic treatment response in breast cancer Open
View article: Real-World Clinical Outcomes With Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer
Real-World Clinical Outcomes With Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer Open
PURPOSE Sacituzumab govitecan (SG) is approved for the treatment of metastatic triple-negative breast cancer (mTNBC). We report the real-world clinical effectiveness and toxicity data of SG in patients with mTNBC. METHODS A multi-instituti…
View article: Detrimental Impact of Chemotherapy Dose Reduction or Discontinuation in Early Stage Triple-Negative Breast Cancer Treated With Pembrolizumab and Neoadjuvant Chemotherapy: A Multicenter Experience
Detrimental Impact of Chemotherapy Dose Reduction or Discontinuation in Early Stage Triple-Negative Breast Cancer Treated With Pembrolizumab and Neoadjuvant Chemotherapy: A Multicenter Experience Open
Our study validates the clinical efficacy of KN-522 regimen; however, we observed a higher incidence of irAEs (54%) in this real-world population. Lower stage and younger age were associated with higher likelihood of achieving pCR. Toxicit…
View article: Effects of Immunotherapy on Quality-of-Life Outcomes in Patients with Gastroesophageal Cancers: A Meta-Analysis of Randomized Controlled Trials
Effects of Immunotherapy on Quality-of-Life Outcomes in Patients with Gastroesophageal Cancers: A Meta-Analysis of Randomized Controlled Trials Open
Background: Immune checkpoint inhibitors (ICIs) have revolutionized cancer care, with increasing data demonstrating improved survival outcomes using ICIs among patients with advanced gastroesophageal cancer (GEC). ICIs are also associated …
View article: CD133 expression is associated with less DNA repair, better response to chemotherapy and survival in ER-positive/HER2-negative breast cancer
CD133 expression is associated with less DNA repair, better response to chemotherapy and survival in ER-positive/HER2-negative breast cancer Open
View article: Targeting the tumor microenvironment to improve clinical outcomes in triple negative breast cancer patients and bridge the current disparity gap
Targeting the tumor microenvironment to improve clinical outcomes in triple negative breast cancer patients and bridge the current disparity gap Open
Triple negative breast cancer (TNBC) is a heterogenous disease that disproportionately affects Black women. TNBC outcomes among Black women are dismal secondary to multiple factors, such as poor healthcare accessibility resulting in delays…
View article: Enhanced cancer cell proliferation and aggressive phenotype counterbalance in breast cancer with high BRCA1 gene expression
Enhanced cancer cell proliferation and aggressive phenotype counterbalance in breast cancer with high BRCA1 gene expression Open
View article: Impact of environmental temperature on the survival outcomes of breast cancer: A SEER-based study
Impact of environmental temperature on the survival outcomes of breast cancer: A SEER-based study Open
View article: CD133 expression is associated with less DNA repair, better response to chemotherapy and survival in ER-positive/HER2-negative breast cancer
CD133 expression is associated with less DNA repair, better response to chemotherapy and survival in ER-positive/HER2-negative breast cancer Open
View article: Effects of Immunotherapy on Quality-of-Life Outcomes in Patients with Gastroesophageal Cancers: A Meta-Analysis of Randomized Controlled Trials
Effects of Immunotherapy on Quality-of-Life Outcomes in Patients with Gastroesophageal Cancers: A Meta-Analysis of Randomized Controlled Trials Open
Background Immune checkpoint inhibitors (ICIs) have revolutionized cancer care, with increasing data demonstrating improved survival outcomes using ICIs among patients with advanced gastroesophageal cancer (GEC). ICIs are also associated w…
View article: Higher Inflammatory Response in Hepatocellular Carcinoma is Associated with Immune Cell Infiltration and a Better Outcome
Higher Inflammatory Response in Hepatocellular Carcinoma is Associated with Immune Cell Infiltration and a Better Outcome Open
View article: Predictors of Complete Pathological Response with Chemoimmunotherapy in Triple-Negative Breast Cancer: A Meta-Analysis
Predictors of Complete Pathological Response with Chemoimmunotherapy in Triple-Negative Breast Cancer: A Meta-Analysis Open
Background: Multiple randomized controlled trials (RCTs) have investigated the impact of adding checkpoint inhibitors to neoadjuvant chemotherapy for triple-negative breast cancer (TNBC) patients. However, there is a lack of biomarkers tha…
View article: Facing the conundrum: which first-line therapy should be used for patients with metastatic triple-negative breast cancer carrying germline BRCA mutation?
Facing the conundrum: which first-line therapy should be used for patients with metastatic triple-negative breast cancer carrying germline BRCA mutation? Open
Pembrolizumab combined with chemotherapy has been established as the preferred first-line therapy for treating metastatic triple-negative breast cancer (mTNBC) with programmed cell death ligand-1 (PD-L1)-positive disease since its approval…
View article: Association between Environmental Temperature and Survival in Gastroesophageal Cancers: A Population Based Study
Association between Environmental Temperature and Survival in Gastroesophageal Cancers: A Population Based Study Open
Background: Cold stress suppresses antitumor response in animal models, leading to tumor growth. Recent studies have also shown a negative correlation between the average annual temperature (AAT) and cancer incidence. We hypothesized that …
View article: Area Deprivation Index (ADI) among Patients with Breast Cancer in Buffalo
Area Deprivation Index (ADI) among Patients with Breast Cancer in Buffalo Open
View article: Impact of Environmental Temperature on Clinical Outcomes and Tumor Microenvironment of Early-Stage Breast Cancer
Impact of Environmental Temperature on Clinical Outcomes and Tumor Microenvironment of Early-Stage Breast Cancer Open
View article: Real-world Analysis of Efficacy and Adverse Events for Advanced Triple Negative Breast Cancer (TNBC) treated with Immune Checkpoint Inhibitors (ICI): A Single Center Experience
Real-world Analysis of Efficacy and Adverse Events for Advanced Triple Negative Breast Cancer (TNBC) treated with Immune Checkpoint Inhibitors (ICI): A Single Center Experience Open
BACKGROUND showed that adding pembrolizumab (P) to chemotherapy improved overall survival (OS) and progression-free survival (PFS) in advanced PDL-1+ TNBC.Conversely, Atezolizumab (A) did not exhibit an OS benefit in IMPASSION-130.Gaining …
View article: Racial and Ethnic Disparity in Preoperative Chemosensitivity and Survival in Patients With Early-Stage Breast Cancer
Racial and Ethnic Disparity in Preoperative Chemosensitivity and Survival in Patients With Early-Stage Breast Cancer Open
Importance It remains unclear what survival benefit is associated with preoperative chemosensitivity after receiving neoadjuvant chemotherapy (NACT) among patients with resectable breast cancer from diverse racial and ethnic backgrounds. O…
View article: 341P Impact of environmental temperature on clinical outcomes of early-stage breast cancer (BC)
341P Impact of environmental temperature on clinical outcomes of early-stage breast cancer (BC) Open
View article: 2391P Impact of perioperative chemotherapy on survival and pathological stage in muscle-invasive micropapillary urothelial bladder cancer
2391P Impact of perioperative chemotherapy on survival and pathological stage in muscle-invasive micropapillary urothelial bladder cancer Open
View article: Emerging resistance <i>vs.</i> losing response to immune check point inhibitors in renal cell carcinoma: two differing phenomena
Emerging resistance <i>vs.</i> losing response to immune check point inhibitors in renal cell carcinoma: two differing phenomena Open
The introduction of immune checkpoint inhibitor (ICI) has revolutionized the treatment of metastatic renal cell carcinoma (mRCC) and has dramatically improved the outcomes of patients. The use of monotherapy or combinations of ICIs targeti…
View article: The extracellular matrix in hepatocellular carcinoma: Mechanisms and therapeutic vulnerability
The extracellular matrix in hepatocellular carcinoma: Mechanisms and therapeutic vulnerability Open