Asako Tan
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View article: Optimizing mouse metatranscriptome profiling by selective removal of redundant nucleic acid sequences
Optimizing mouse metatranscriptome profiling by selective removal of redundant nucleic acid sequences Open
Metatranscriptome (MetaT) sequencing is a critical tool for profiling the dynamic metabolic functions of microbiomes. In addition to taxonomic information, MetaT also provides real-time gene expression data of both host and microbial popul…
View article: Optimizing mouse metatranscriptome profiling by selective removal of redundant nucleic acid sequences
Optimizing mouse metatranscriptome profiling by selective removal of redundant nucleic acid sequences Open
Metatranscriptome (MetaT) sequencing is a critical tool for profiling the dynamic metabolic functions of microbiomes. In addition to taxonomic information, MetaT also provides real-time gene expression data of both host and microbial popul…
View article: Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain
Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain Open
Intron branchpoint (BP) recognition by the U2 snRNP is a critical step of splicing, vulnerable to recurrent cancer mutations and bacterial natural product inhibitors. The BP binds a conserved pocket in the SF3B1 (human) or Hsh155 (yeast) U…
View article: Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain
Broad variation in response of individual introns to splicing inhibitors in a humanized yeast strain Open
Intron branch point (BP) recognition by the U2 snRNP is a critical step of splicing, vulnerable to recurrent cancer mutations and bacterial natural product inhibitors. The BP binds a conserved pocket in the SF3B1 (human) or Hsh155 (yeast) …
View article: Rational probe design for efficient rRNA depletion and improved metatranscriptomic analysis of human microbiomes
Rational probe design for efficient rRNA depletion and improved metatranscriptomic analysis of human microbiomes Open
Background The microbiota that colonize the human gut and other tissues are dynamic, varying both in composition and functional state between individuals and over time. In studying the function of the human microbiome and the mechanisms of…
View article: Genome Sequencing of Sewage Detects Regionally Prevalent SARS-CoV-2 Variants
Genome Sequencing of Sewage Detects Regionally Prevalent SARS-CoV-2 Variants Open
Viral genome sequencing has guided our understanding of the spread and extent of genetic diversity of SARS-CoV-2 during the COVID-19 pandemic. SARS-CoV-2 viral genomes are usually sequenced from nasopharyngeal swabs of individual patients …
View article: Additional file of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum
Additional file of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum Open
Additional file of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum
View article: Additional file 2 of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum
Additional file 2 of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum Open
Additional file 2:SNPs between HB3 and Dd2(XLS 2 MB)
View article: Genome sequencing of sewage detects regionally prevalent SARS-CoV-2 variants
Genome sequencing of sewage detects regionally prevalent SARS-CoV-2 variants Open
Viral genome sequencing has guided our understanding of the spread and extent of genetic diversity of SARS-CoV-2 during the COVID-19 pandemic. SARS-CoV-2 viral genomes are usually sequenced from nasopharyngeal swabs of individual patients …
View article: Additional file of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum
Additional file of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum Open
Additional file of High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum
View article: Simultaneous genome-wide gene expression and transcript isoform profiling in the human malaria parasite
Simultaneous genome-wide gene expression and transcript isoform profiling in the human malaria parasite Open
Gene expression DNA microarrays have been vital for characterizing whole-genome transcriptional profiles. Nevertheless, their effectiveness relies heavily on the accuracy of genome sequences, the annotation of gene structures, and the sequ…
View article: Prediction of fine-tuned promoter activity from DNA sequence
Prediction of fine-tuned promoter activity from DNA sequence Open
The quantitative prediction of transcriptional activity of genes using promoter sequence is fundamental to the engineering of biological systems for industrial purposes and understanding the natural variation in gene expression. To catalyz…