Asghar Parsaei
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View article: Probiotic-enhanced chemotherapy: Lactobacillus fermentum synergizes with vincristine to induce apoptosis via dual pathway activation in human cancer cells
Probiotic-enhanced chemotherapy: Lactobacillus fermentum synergizes with vincristine to induce apoptosis via dual pathway activation in human cancer cells Open
L. fermentum enhanced vincristine-induced apoptosis and reduced the required drug dose, which may contribute to lowering vincristine-associated toxicity. These findings require confirmation through in vivo studies.
View article: Chaetoceros socialis extract triggers apoptosis in oral and colorectal cancer cells through PI3K/AKT/mTOR pathway modulation
Chaetoceros socialis extract triggers apoptosis in oral and colorectal cancer cells through PI3K/AKT/mTOR pathway modulation Open
Background: Conventional chemotherapy remains a cornerstone in cancer treatment; however, its clinical efficacy is limited by severe side effects on normal tissues. This has encouraged interest in natural compounds with selective anticance…
View article: Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach Open
Introduction: Breast cancer represents a significant global health challenge, underscoring the need for innovative therapeutic strategies. This study explores the therapeutic potential of etoposide (ETO)-loaded graphene oxide (GO) nanogels…
View article: Postbiotic metabolites derived from lactobacillus fermentum as potent antiproliferative bioresources on HeLa cells with promising biocompatibility
Postbiotic metabolites derived from lactobacillus fermentum as potent antiproliferative bioresources on HeLa cells with promising biocompatibility Open
View article: Isolated <i>Lactobacillus fermentum</i> Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway.
Isolated <i>Lactobacillus fermentum</i> Ab.RS22 from traditional dairy products inhibits HeLa cervical cancer cell proliferation and modulates apoptosis by the PTEN-Akt pathway. Open
Our findings showed that L. fermentum Ab.RS22 could dose-dependently inhibit the proliferation of the HeLa cells. Its apoptotic effect was confirmed via modulating PTEN/p53/Akt gene expression and activation of the cas…
View article: Apoptotic Effect of Phycocyanin on HT-29 Colon Cancer through Activation of Caspase Enzymes and P53 Cell Signaling Pathway
Apoptotic Effect of Phycocyanin on HT-29 Colon Cancer through Activation of Caspase Enzymes and P53 Cell Signaling Pathway Open
Apoptotic Effect of Phycocyanin on HT-29 Colon Cancer through Activation of Caspase Enzymes and P53 Cell Signaling Pathway