Ashim Das
YOU?
Author Swipe
View article: Molecular Docking and Computational Analysis of Chemical Constituents of Tinospora cordifolia as Potential DPP-4 Inhibitors for Diabetes Management.
Molecular Docking and Computational Analysis of Chemical Constituents of Tinospora cordifolia as Potential DPP-4 Inhibitors for Diabetes Management. Open
Tinospora cordifolia, a well-known medicinal plant, has been traditionally used for its wide range of therapeutic properties, including antidiabetic effects. In this study, we investigated the potential of five key chemical constituents of…
View article: Isolated Scapular Spine Involvement: A Rare Presentation of Osteoarticular Tuberculosis
Isolated Scapular Spine Involvement: A Rare Presentation of Osteoarticular Tuberculosis Open
Introduction: Tuberculosis (TB) is an endemic disease worldwide, especially in the Indian subcontinent. Most common locations for osteoarticular TB are the vertebral column and the hip. TB of flat bones, such as the scapula, is an extremel…
View article: Effectiveness of Pre-Operative Education on Post-Operative Anxiety Outcome in Parents Having Children Undergoing Cardiac Surgeries in Peshawar
Effectiveness of Pre-Operative Education on Post-Operative Anxiety Outcome in Parents Having Children Undergoing Cardiac Surgeries in Peshawar Open
Around the globe, 1.3 million babies are born with congenital heart defects (CHD); among them, 70% of the patients go for medical or surgical intervention. Parents of children undergoing any intervention usually experience psychological st…
View article: <i>In-vitro</i> antioxidant and anti-inflammatory activity of <i>Annona muricata</i> leaf extract mediated silver nanoparticles
<i>In-vitro</i> antioxidant and anti-inflammatory activity of <i>Annona muricata</i> leaf extract mediated silver nanoparticles Open
The reactive oxygen species produced by the action of free radicals on molecular oxygen causes serious inflammation conditions. Non-steroidal anti-inflammatory drugs which are commonly prescribed for the treatment of inflammatory condition…
View article: The Use of CECT in the Diagnosis of Intestinal Obstruction: A Case of Difficult Diagnosis in a Strangulated Left Femoral Hernia
The Use of CECT in the Diagnosis of Intestinal Obstruction: A Case of Difficult Diagnosis in a Strangulated Left Femoral Hernia Open
A BSTRACT A femoral hernia is an uncommon and acquired hernia in the groin. Its incidence in adults is 2%–8% of all abdominal wall hernias, and it has a female-to-male ratio of 1.8:1. It is usually found in elderly patients and is associat…
View article: Cancer associated fibroblasts modulate the cytotoxicity of anti-cancer drugs in breast cancer: An in vitro study
Cancer associated fibroblasts modulate the cytotoxicity of anti-cancer drugs in breast cancer: An in vitro study Open
BACKGROUND: Tumour microenvironment (TME) contributes to resistance to anti-cancer drugs through multiple mechanisms including secretion of pro-survival factors by cancer associated fibroblasts (CAFs). In this study, we determined the chem…
View article: Acute liver failure caused by lymphocyte-depleted Hodgkin lymphoma in tuberculosis and HIV-infected patient
Acute liver failure caused by lymphocyte-depleted Hodgkin lymphoma in tuberculosis and HIV-infected patient Open
The lymphocyte-depleted classic Hodgkin lymphoma (LDCHL), the rarest subtype of classic Hodgkin lymphoma (CHL), is usually diagnosed at an advanced stage (stage IV) and one that unusually involves the liver, causing a rapidly progressive c…
View article: Clear cell myomelanocytic tumor of ligamentum teres
Clear cell myomelanocytic tumor of ligamentum teres Open
Clear cell myomelanocytic tumor (CCMMT) of the falciform ligament/ligamentum teres is a rare hepatic tumor, a variant of the perivascular epithelioid cell tumor (PEComa) family. CCMMT is the rarest variant of hepatic PEComas. Only a few ca…
View article: Lean Indian patients with non-alcoholic fatty liver disease (NAFLD) have less metabolic risk factors but similar liver disease severity as non-lean patients with NAFLD
Lean Indian patients with non-alcoholic fatty liver disease (NAFLD) have less metabolic risk factors but similar liver disease severity as non-lean patients with NAFLD Open
Introduction Although most patients with NAFLD are obese or overweight, some are lean with normal BMI. Our aim was to assess differences in clinicopathological profile and liver disease severity among lean and non-lean NAFLD. Methods Data …
View article: HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults
HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults Open
Autoimmune hepatitis (AIH) is a chronic and progressive disease of the liver. This is a multifactorial autoimmune disease with both environmental factors and genetic factors playing a role in its pathogenesis. Certain environmental agents …
View article: "Missed Gall Bladder Cancer During Cholecystectomy - What Price Do We Pay?" An Experience of a Tertiary Care Center from India
"Missed Gall Bladder Cancer During Cholecystectomy - What Price Do We Pay?" An Experience of a Tertiary Care Center from India Open
Background: The incidence of missed gall bladder cancer (GBC) is increasing with rising numbers of cholecystectomies in North India. Most of these are misrepresented as Incidental gall bladder (IGBC) cancer at referral. Our aim was to anal…
View article: Development of a cost-effective ex vivo lung perfusion system for lung transplantation in India
Development of a cost-effective ex vivo lung perfusion system for lung transplantation in India Open
Background & objectives: Standard donor lung preservation with cold flush and storage allows up to six hours between retrieval of lungs from the donor and transplantation in the recipient. Ex vivo lung perfusion (EVLP) systems mimic physio…
View article: Synergistic collagen-condiment: Streptococcal collagen-like (Scl) protein in cell-adhesion and diabetic wound-closure matrix
Synergistic collagen-condiment: Streptococcal collagen-like (Scl) protein in cell-adhesion and diabetic wound-closure matrix Open
Group A streptococcus (GAS), Streptococcus pyogenes manifests plethora of diseases through its explicit virulence factors. Among these, the recently deciphered MSCRAMMs, Streptococcal collagen-like (Scls) adhesins are most studied proteins…
View article: Programmed death-ligand 1 expression and tumor-infiltrating lymphocytes in non-small cell lung cancer: association with clinicopathologic parameters
Programmed death-ligand 1 expression and tumor-infiltrating lymphocytes in non-small cell lung cancer: association with clinicopathologic parameters Open
Background: Data on the prevalence of programmed death-ligand 1 (PD-L1) expression and tumor-infiltrating lymphocytes (TILs) in non–small cell lung cancer (NSCLC) and their clinical significance in Indian patients are limited. Methods: New…
View article: Bird Fancier's Lung Disease in a Child with Chronic Respiratory Illness
Bird Fancier's Lung Disease in a Child with Chronic Respiratory Illness Open
Bird fancier's lung is a type of hypersensitivity pneumonitis and rare interstitial lung disease in children. It has 3 forms of presentation viz. acute, subacute, and chronic. Here we present a child with chronic hypersensitivity pneumonit…
View article: Primary Spinal Intradural Ewing's Sarcoma: Hemorrhagic Presentation with Acute Neurological Deterioration in Two Pediatric Patients
Primary Spinal Intradural Ewing's Sarcoma: Hemorrhagic Presentation with Acute Neurological Deterioration in Two Pediatric Patients Open
Extraosseous primary spinal intradural Ewing's sarcoma (ES) is an unusual entity. Bleed within such tumors with acute neurological worsening is extremely rare, especially in the pediatric age. In this article, we present two children with …
View article: Bendamustine in combination with ifosfamide, etoposide, and vinorelbine (VIBE) is an effective salvage regimen for heavily pre-treated patients with relapsed or refractory Hodgkin lymphoma: a single-center experience
Bendamustine in combination with ifosfamide, etoposide, and vinorelbine (VIBE) is an effective salvage regimen for heavily pre-treated patients with relapsed or refractory Hodgkin lymphoma: a single-center experience Open
In this retrospective analysis, the combination regimen, VIBE, has shown good efficacy in heavily pre-treated patients with RRHL without compromising stem cell collection. These encouraging results provide a rationale for further developme…
View article: Fine-Needle Aspiration Diagnosis of Lymphoma Based on Cytomorphology Alone
Fine-Needle Aspiration Diagnosis of Lymphoma Based on Cytomorphology Alone Open
Context: Fine-needle aspiration cytology (FNAC) is a rapid and accurate first-line diagnostic modality in lymphadenopathy. Aims: To determine the utility of FNAC for the diagnosis of lymphoma and highlight the various pitfalls in morpholog…
View article: Assessment of risk of malignancy by application of the proposed Sydney system for classification and reporting lymph node cytopathology
Assessment of risk of malignancy by application of the proposed Sydney system for classification and reporting lymph node cytopathology Open
BACKGROUND Fine‐needle aspiration cytology (FNAC) is one of the most commonly used techniques for evaluating lymphadenopathy. Recently, the Sydney system was proposed for assessing the performance, classification, and reporting of lymph no…
View article: Crossroad of infection and autoimmunity in acute liver failure: a case report
Crossroad of infection and autoimmunity in acute liver failure: a case report Open
Background Acute liver failure (ALF) is a syndromic diagnosis, consisting of jaundice, coagulopathy, and any degree of encephalopathy in a patient without pre-existing liver disease within 26 weeks of the onset of symptoms. Autoimmune hepa…