Ashis Biswas
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View article: Hsp16.3ΔC4, a C-terminal truncated mutant, confers strong cellular and humoral immunity against pulmonary tuberculosis
Hsp16.3ΔC4, a C-terminal truncated mutant, confers strong cellular and humoral immunity against pulmonary tuberculosis Open
Despite its widespread use, the Bacillus Calmette-Guérin (BCG) vaccine offers limited and variable protection against adult pulmonary tuberculosis, highlighting the urgent need for next-generation vaccines that can induce durable protectiv…
View article: Human-Aware Robot Collaborative Task Planning Using Artificial Potential Field and DQN Reinforcement Learning
Human-Aware Robot Collaborative Task Planning Using Artificial Potential Field and DQN Reinforcement Learning Open
This paper presents a novel way for Robot-Robot-Human interaction in a shared workspace for collaborative tasks and uses a multi-modal means of communication that includes hand gestures, voice commands, end-effector gestures, and marker tr…
View article: Editorial: Influence of mutations, stresses and post-translational modifications on the structure and function of heat shock proteins and their relationship with various diseases
Editorial: Influence of mutations, stresses and post-translational modifications on the structure and function of heat shock proteins and their relationship with various diseases Open
EDITORIAL article Front. Mol. Biosci., 20 October 2023Sec. Protein Biochemistry for Basic and Applied Sciences Volume 10 - 2023 | https://doi.org/10.3389/fmolb.2023.1310272
View article: Impact of nanoparticles on amyloid β-induced Alzheimer’s disease, tuberculosis, leprosy and cancer: a systematic review
Impact of nanoparticles on amyloid β-induced Alzheimer’s disease, tuberculosis, leprosy and cancer: a systematic review Open
Nanotechnology is an interdisciplinary domain of science, technology and engineering that deals with nano-sized materials/particles. Usually, the size of nanoparticles lies between 1 and 100 nm. Due to their small size and large surface ar…
View article: Editorial: The Role of Mutations, Stresses and Post-Translational Modifications in the Structure and Function of Small Heat Shock Proteins and Their Relationship with Different Human Diseases
Editorial: The Role of Mutations, Stresses and Post-Translational Modifications in the Structure and Function of Small Heat Shock Proteins and Their Relationship with Different Human Diseases Open
EDITORIAL article Front. Mol. Biosci., 08 June 2022Sec. Protein Biochemistry for Basic and Applied Sciences Volume 9 - 2022 | https://doi.org/10.3389/fmolb.2022.922959
View article: Role of ATP-Small Heat Shock Protein Interaction in Human Diseases
Role of ATP-Small Heat Shock Protein Interaction in Human Diseases Open
Adenosine triphosphate (ATP) is an important fuel of life for humans and Mycobacterium species. Its potential role in modulating cellular functions and implications in systemic, pulmonary, and ocular diseases is well studied. Plasma ATP ha…
View article: Interaction of constituents of MDT regimen for leprosy with <i>Mycobacterium leprae</i> HSP18: impact on its structure and function
Interaction of constituents of MDT regimen for leprosy with <i>Mycobacterium leprae</i> HSP18: impact on its structure and function Open
Mycobacterium leprae , the causative organism of leprosy, harbors many antigenic proteins, and one such protein is the 18‐kDa antigen. This protein belongs to the small heat shock protein family and is commonly known as HSP18. Its chaperon…
View article: Depicting the inhibitory potential of polyphenols from <i>Isatis indigotica</i> root against the main protease of SARS CoV-2 using computational approaches
Depicting the inhibitory potential of polyphenols from <i>Isatis indigotica</i> root against the main protease of SARS CoV-2 using computational approaches Open
The pandemic disease COVID-19, caused by SARS CoV-2, has created a global crisis. Presently, researchers across the globe are in a quest to identify/develop drugs or vaccines by targeting different non-structural proteins (Nsps) of SARS Co…
View article: Computer aided identification of potential SARS CoV-2 main protease inhibitors from diterpenoids and biflavonoids of <i>Torreya nucifera</i> leaves
Computer aided identification of potential SARS CoV-2 main protease inhibitors from diterpenoids and biflavonoids of <i>Torreya nucifera</i> leaves Open
SARS CoV-2 is the causative agent of the pandemic disease COVID-19. There is an urgent need for effective drugs or vaccines which can effectively combat this outbreak. The main protease (Mpro), a key component for the SARS CoV-2 replicatio…
View article: Potential therapeutic use of corticosteroids as SARS CoV-2 main protease inhibitors: a computational study
Potential therapeutic use of corticosteroids as SARS CoV-2 main protease inhibitors: a computational study Open
The outbreak of COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), represents a pandemic threat to global public health. To date, ∼530,000 people died of this disease worldwide. Presently, researchers/clinici…
View article: Identification of polyphenols from<i>Broussonetia papyrifera</i>as SARS CoV-2 main protease inhibitors using<i>in silico</i>docking and molecular dynamics simulation approaches
Identification of polyphenols from<i>Broussonetia papyrifera</i>as SARS CoV-2 main protease inhibitors using<i>in silico</i>docking and molecular dynamics simulation approaches Open
The current COVID-19 pandemic is caused by SARS CoV-2. To date, ∼463,000 people died worldwide due to this disease. Several attempts have been taken in search of effective drugs to control the spread of SARS CoV-2 infection. The main prote…
View article: Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors – an <i>in silico</i> docking and molecular dynamics simulation study
Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors – an <i>in silico</i> docking and molecular dynamics simulation study Open
Coronavirus disease 2019 (COVID-19) is a viral respiratory disease which caused global health emergency and announced as pandemic disease by World Health Organization. Lack of specific drug molecules or treatment strategy against this dise…
View article: Cover Image, Volume 88, Issue 6
Cover Image, Volume 88, Issue 6 Open
Obverse Cover: The cover image is based on the Original Article The impact of different mutations at arginine141 on the structure, subunit exchange dynamics and chaperone activity of Hsp16.3 by Ashis Biswas et al., https://doi.org/10.1002/…
View article: CCDC 1491690: Experimental Crystal Structure Determination
CCDC 1491690: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1491689: Experimental Crystal Structure Determination
CCDC 1491689: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1491691: Experimental Crystal Structure Determination
CCDC 1491691: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1491692: Experimental Crystal Structure Determination
CCDC 1491692: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: The C‐terminal extension of <i>Mycobacterium tuberculosis</i> Hsp16.3 regulates its oligomerization, subunit exchange dynamics and chaperone function
The C‐terminal extension of <i>Mycobacterium tuberculosis</i> Hsp16.3 regulates its oligomerization, subunit exchange dynamics and chaperone function Open
Mycobacterium tuberculosis is a human pathogen that secretes a major immunodominant antigen, namely Hsp16.3, throughout the course of infection. Hsp16.3 belongs to the small heat shock protein family and exhibits a molecular chaperone func…
View article: CCDC 1482859: Experimental Crystal Structure Determination
CCDC 1482859: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1482860: Experimental Crystal Structure Determination
CCDC 1482860: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: MGO reacts with proteins to form AGEs, like, hydroimidazolone, argpyrimidine and MOLD in tissue proteins.
MGO reacts with proteins to form AGEs, like, hydroimidazolone, argpyrimidine and MOLD in tissue proteins. Open
MGO reacts with proteins to form AGEs, like, hydroimidazolone, argpyrimidine and MOLD in tissue proteins.
View article: Role of Subunit Exchange and Electrostatic Interactions on the Chaperone Activity of Mycobacterium leprae HSP18
Role of Subunit Exchange and Electrostatic Interactions on the Chaperone Activity of Mycobacterium leprae HSP18 Open
Mycobacterium leprae HSP18, a major immunodominant antigen of M. leprae pathogen, is a small heat shock protein. Previously, we reported that HSP18 is a molecular chaperone that prevents aggregation of different chemically and thermally st…
View article: Interaction of ATP with a Small Heat Shock Protein from Mycobacterium leprae: Effect on Its Structure and Function
Interaction of ATP with a Small Heat Shock Protein from Mycobacterium leprae: Effect on Its Structure and Function Open
Adenosine-5’-triphosphate (ATP) is an important phosphate metabolite abundantly found in Mycobacterium leprae bacilli. This pathogen does not derive ATP from its host but has its own mechanism for the generation of ATP. Interestingly, this…
View article: CCDC 1002348: Experimental Crystal Structure Determination
CCDC 1002348: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1049349: Experimental Crystal Structure Determination
CCDC 1049349: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu(<scp>i</scp>/<scp>ii</scp>) complexes of thiosemicarbazone: special emphasis on their interactions with DNA
Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu(<span>i</span>/<span>ii</span>) complexes of thiosemicarbazone: special emphasis on their interactions with DNA Open
The interactions of four Cu-TSC complexes with DNA & their cytotoxicity studies against the HeLa cell have been reported.
View article: CCDC 1007036: Experimental Crystal Structure Determination
CCDC 1007036: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …