Ashley E. Clements
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Biochemometric Analysis of Bat Skin Microbiome-Associated <i>Streptomyces buecherae</i> Identifies Polyether Antibiotics Active Against the Bat Pathogen <i>Pseudogymnoascus destructans</i> Open
Background Bats, critical to controlling insect populations, harbor unique immune systems that can provide insight into preventing and treating diseases. Unfortunately, white-nose syndrome (WNS), caused by the fungus Pseudogymnoascus destr…
Subterranean marvels: microbial communities in caves and underground mines and their promise for natural product discovery Open
Subterranean microbial communities possess unique and untapped biosynthetic potential.
View article: Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster
Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster Open
Introduction Fungi biosynthesize chemically diverse secondary metabolites with a wide range of biological activities. Natural product scientists have increasingly turned towards bioinformatics approaches, combining metabolomics and genomic…