Ryan Hamilton
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View article: Antimicrobial stewardship curricula for undergraduate healthcare education applicable to the UK: a full review of online resources
Antimicrobial stewardship curricula for undergraduate healthcare education applicable to the UK: a full review of online resources Open
Background Antimicrobials are the cornerstone of modern medicine, used to treat millions of people worldwide. Antimicrobial stewardship (AMS) is included as part of healthcare professional (HCP) undergraduate (UG) curricula; however, these…
View article: Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients: The PEACH mixed methods study
Procalcitonin evaluation of antibiotic use in COVID-19 hospitalised patients: The PEACH mixed methods study Open
Background Early in the COVID-19 pandemic, there was concern about potentially unnecessary antibiotic prescribing in the National Health Service. Procalcitonin testing was being used in some hospitals to guide antibiotic use. This study ai…
View article: P14 Preparing the future pharmacy workforce: competency-based undergraduate curricula for teaching, learning and assessment with a focus on antimicrobial stewardship
P14 Preparing the future pharmacy workforce: competency-based undergraduate curricula for teaching, learning and assessment with a focus on antimicrobial stewardship Open
Background Competency-based teaching, learning and assessment underpins the requirements for initial training and education of pharmacists (IETPs) in the UK as set by the General Pharmaceutical Council (GPhC). This competency-based pedagog…
View article: Preparing the future pharmacy workforce: competency-based undergraduate curricula for teaching, learning and assessment with a focus on antimicrobial stewardship
Preparing the future pharmacy workforce: competency-based undergraduate curricula for teaching, learning and assessment with a focus on antimicrobial stewardship Open
Introduction Competency-based teaching, learning and assessment underpins the requirements for initial training and education of pharmacists (IETPs) in the UK and is set by the General Pharmaceutical Council (GPhC). This competency-based p…
View article: A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19
A retrospective propensity-score-matched cohort study of the impact of procalcitonin testing on antibiotic use in hospitalized patients during the first wave of COVID-19 Open
Background Procalcitonin (PCT) is a blood marker used to help diagnose bacterial infections and guide antibiotic treatment. PCT testing was widely used/adopted during the COVID-19 pandemic in the UK. Objectives Primary: to measure the diff…
View article: Evaluation of antibiotics returned for safe disposal during and after a community pharmacy antibiotic amnesty campaign
Evaluation of antibiotics returned for safe disposal during and after a community pharmacy antibiotic amnesty campaign Open
Background Community pharmacies in England offer convenient and safe disposal of unwanted medicines, including antimicrobials, and better uptake of this service could limit environmental antimicrobial resistance. However, there is limited …
View article: Nurses' attitudes, behaviours, and enablers of intravenous to oral switching (IVOS) of antibiotics: a mixed-methods survey of nursing staff in secondary care hospitals across the Midlands region of England
Nurses' attitudes, behaviours, and enablers of intravenous to oral switching (IVOS) of antibiotics: a mixed-methods survey of nursing staff in secondary care hospitals across the Midlands region of England Open
Nursing staff suggest IVOS to other clinicians, but more education and resources are needed to enable and empower them in this role.
View article: Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study)
Developing a model for decision-making around antibiotic prescribing for patients with COVID-19 pneumonia in acute NHS hospitals during the first wave of the COVID-19 pandemic: qualitative results from the Procalcitonin Evaluation of Antibiotic use in COVID-19 Hospitalised patients (PEACH Study) Open
Objective To explore and model factors affecting antibiotic prescribing decision-making early in the pandemic. Design Semistructured qualitative interview study. Setting National Health Service (NHS) trusts/health boards in England and Wal…
View article: Understanding the lived-experience and support-needs of people living with antimicrobial resistance in the UK: an interpretative phenomenological analysis
Understanding the lived-experience and support-needs of people living with antimicrobial resistance in the UK: an interpretative phenomenological analysis Open
Background In the UK nearly 54,000 infections were caused by serious resistant bacteria in 2022. While the impact on patients during hospital admissions are known, there is little research on the long-term impact on those identified as hav…
View article: Implementation of the national antimicrobial stewardship competencies for UK undergraduate healthcare professional education within undergraduate pharmacy programmes: a survey of UK schools of pharmacy
Implementation of the national antimicrobial stewardship competencies for UK undergraduate healthcare professional education within undergraduate pharmacy programmes: a survey of UK schools of pharmacy Open
Background Pharmacists play a key role in antimicrobial stewardship (AMS). Consensus-based national AMS competencies for undergraduate healthcare professionals in the UK reflect the increasing emphasis on competency-based healthcare profes…
View article: Research capability and aspirations of antimicrobial pharmacists: survey of UKCPA pin membership
Research capability and aspirations of antimicrobial pharmacists: survey of UKCPA pin membership Open
Introduction The United Kingdom Clinical Pharmacist Association Pharmacy Infection Network (UKCPA PIN) is the community of pharmacy professionals with an interest or specialism in infection management. As we come out of the Covid-19 pandem…
View article: Systematic review of high-dose amikacin regimens for the treatment of Gram-negative infections based on EUCAST dosing recommendations
Systematic review of high-dose amikacin regimens for the treatment of Gram-negative infections based on EUCAST dosing recommendations Open
PROSPERO (CRD42021250022).
View article: Systematic review of high-dose amikacin regimens for the treatment of Gram-negative infections based on EUCAST dosing recommendations
Systematic review of high-dose amikacin regimens for the treatment of Gram-negative infections based on EUCAST dosing recommendations Open
Background Amikacin is an aminoglycoside with activity against Gram negative pathogens. Updated EUCAST amikacin breakpoints for Enterobacterales and Pseudomonas aeruginosa included revised dosing recommendations of 25-30mg/kg to achieve ke…
View article: Experiences of an Exercise Program: Perspectives from Breast Cancer Survivors
Experiences of an Exercise Program: Perspectives from Breast Cancer Survivors Open
Few studies have examined how breast cancer survivors experience an individually tailored group exercise program designed to help mitigate physical and psychosocial challenges and improve health outcomes. This research used qualitative int…
View article: Harnessing the wisdom of crowds can improve guideline compliance of antibiotic prescribers and support antimicrobial stewardship
Harnessing the wisdom of crowds can improve guideline compliance of antibiotic prescribers and support antimicrobial stewardship Open
Antibiotic overprescribing is a global challenge contributing to rising levels of antibiotic resistance and mortality. We test a novel approach to antibiotic stewardship. Capitalising on the concept of “wisdom of crowds”, which states that…
View article: Recommended antimicrobial therapy for common inpatient infections: a comparative review of guidelines across 51 hospital trusts in England
Recommended antimicrobial therapy for common inpatient infections: a comparative review of guidelines across 51 hospital trusts in England Open
Background The number of different antimicrobial recommendations between hospital trusts for the same indication in England is unknown. Aim We aimed to evaluate the heterogeneity of antimicrobial recommendations for seven common inpatient …
View article: Treating infections caused by carbapenemase-producing Enterobacterales (CPE): a pragmatic approach to antimicrobial stewardship on behalf of the UKCPA Pharmacy Infection Network (PIN)
Treating infections caused by carbapenemase-producing Enterobacterales (CPE): a pragmatic approach to antimicrobial stewardship on behalf of the UKCPA Pharmacy Infection Network (PIN) Open
The emergence of carbapenemase-producing Enterobacterales (CPE) as a major cause of invasive infection both within the UK and internationally poses a very real concern for all providers of healthcare. The burden of morbidity and mortality …
View article: Antimicrobial stewardship ward rounds led by junior members of the healthcare team improve patient care
Antimicrobial stewardship ward rounds led by junior members of the healthcare team improve patient care Open
Background Reported Antimicrobial Stewardship (AMS) ward rounds and review initiatives utilise consultant microbiologists or consultant ID physicians with or without senior antimicrobial pharmacists (AMP). There is sparse evidence regardin…
View article: Development and Initial Evaluation of a national Infection Prevention and Antimicrobial Resistance programme for UK Girlguiding and Scouts
Development and Initial Evaluation of a national Infection Prevention and Antimicrobial Resistance programme for UK Girlguiding and Scouts Open
Background Between 2016-18, infection prevention (IP) and antimicrobial resistance (AMR) projects were developed independently by Girlguiding and Scout groups across four UK regions. The UK 5-year AMR Action Plan outlines the importance of…
View article: A Critical Analysis of the Delivery of a Psychosocial Workshop for Cancer Survivors with Lymphedema
A Critical Analysis of the Delivery of a Psychosocial Workshop for Cancer Survivors with Lymphedema Open
Secondary lymphedema is a chronic condition that can develop after the treatment of cancer and can often lead to negative psychological and social impairments. When dealing with chronic illness, hoping and coping are interdependent. Previo…
View article: Ibuprofen Intercalation and Release From Different Layered Double Hydroxides
Ibuprofen Intercalation and Release From Different Layered Double Hydroxides Open
The chemical composition of LDHs affects their crystallinity, IBU intercalation and subsequent release.
View article: The development and evaluation of antibacterial polymer-phyllosilicate composite systems for the treatment of infected wounds
The development and evaluation of antibacterial polymer-phyllosilicate composite systems for the treatment of infected wounds Open
Clays and clay minerals (phyllosilicates) have been used for millennia to treat a range of human maladies, such as infected wounds and diseases of the skin. The unique chemistry of phyllosilicates allows them to support the wound environme…
View article: Composing hope through collage: A community-based intervention for cancer survivors living with lymphedema
Composing hope through collage: A community-based intervention for cancer survivors living with lymphedema Open
Secondary lymphedema after cancer may result in distress, yet few interventions exist to support coping skills in this population. As part of a community-based intervention, we piloted the use of creative practices to promote active orient…