Asok Biswas
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View article: MC1R determines healing outcomes in acute and chronic cutaneous wounds
MC1R determines healing outcomes in acute and chronic cutaneous wounds Open
Chronic wounds (CWs) represent a major clinical challenge, characterized by persistent inflammation and failed repair. While proresolving pathways are known to regulate inflammatory responses, their potential dysfunction in CWs remains une…
P158 Merkel cell carcinoma: a retrospective case series of morphological presentations Open
Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine tumour that derives from the Merkel cells within the epidermis. The pathogenesis principally involves cell DNA mutations from long-term ultraviolet (UV) radiation exposure or…
View article: BRAF Mutated and Morphologically Spitzoid Tumors, a Subgroup of Melanocytic Neoplasms Difficult to Distinguish From True Spitz Neoplasms
BRAF Mutated and Morphologically Spitzoid Tumors, a Subgroup of Melanocytic Neoplasms Difficult to Distinguish From True Spitz Neoplasms Open
Drivers of Spitz neoplasms include activating point mutations in HRAS and Spitz-associated genomic fusions. It has become evident that some BRAF -mutated melanocytic neoplasms can morphologically mimic Spitz tumors (STs). These have been t…
Arsenic Toxicity and Tolerance in Plants Open
Contamination of soil and water by the toxic metalloid arsenic is an environmental distress and a critical health concern for plants as well as animals. Arsenic accumulates in different parts of the plant adversely affecting crop productio…
Efficacy of seed priming strategies for enhancing salinity tolerance in plants: An overview of the progress and achievements Open
Soil salinization adversely affects sustainability and productivity of cultivable land by altering seed germination, growth and physio-biochemical attributes consequently limiting agricultural output. To sustain crop productivity, therefor…
MC1R reduces scarring and rescues stalled healing in a preclinical chronic wound model Open
Cutaneous healing results in scarring with significant functional and psychological sequelae, while chronic non-healing wounds represent repair failure often with devastating consequences, including amputation and death. Due to a lack of e…
Comparative study of silicon and selenium to modulate chloroplast pigments levels, Hill activity, photosynthetic parameters and carbohydrate metabolism under arsenic stress in rice seedlings Open
Arsenic (As) in groundwater severely harms global economic development by affecting growth and productivity of agricultural crops that causes human health risk. The comparative influence of silicon (Si) and selenium (Se) to modulate pigmen…
Comparative study on the influence of silicon and selenium to mitigate arsenic induced stress by modulating TCA cycle, GABA and polyamine synthesis in rice seedlings Open
Arsenic contamination of groundwater is a major concern for its use as drinking water and crop irrigation in many regions of the world. Arsenic is absorbed by rice plants from arsenic contaminated water during irrigation, hampers growth an…
Modulation of ascorbate-glutathione cycle by selenate and sulphate treatments in the seedlings of two rice (Oryza sativa L.) cultivars Open
The trace element Selenium (Se) has a dual role in the growth and metabolism of plants. Low concentration of selenium (2 ?M selenate) promotes growth and counteracts the detrimental effects of abiotic stress as opposed to higher levels (?1…
Potential of Seed Halopriming in Mitigating NaCl-induced Adversities on Nitrogen Metabolism in Legume Crops Open
Background: Salinity is a major threat that impairs legume growth and development worldwide. Therefore, present study was aimed to determine the potential of seed halopriming in relieving NaCl-induced disturbances on nitrogen metabolism of…
Trichoblastic carcinosarcoma with panfollicular differentiation (panfollicular carcinosarcoma) and <span><i>CTNNB1</i></span> (beta‐catenin) mutation Open
We present a case of trichoblastic carcinosarcoma with panfollicular differentiation. An 80‐year‐old man presented with a lesion on the left ear, which had been present for several months. Histopathology revealed a well‐demarcated neoplasm…
ISOLATION, PURIFICATION AND PARTIAL CHARACTERIZATION OF LOW MOLECULAR WEIGHT PEPTIDES FROM NONPRIMED AND HALOPRIMED SEEDLINGS of Vigna mungo L. AND Cajanus cajan L. AND THEIR IMPACT ON PHYSIOLOGICAL ASPECTS UNDER NaCl EXPOSURE Open
Plants confront an array of environmental stresses by tightly regulating their signalling pathways involving low molecular weight peptide synthesis.In the conducted study, initially growth parameters and ion contents were measured from sal…
Influence of Selenium on Growth, Antioxidants Production and Physiological Parameters of Rice (<i>Oryza sativa</i> L.) Seedlings and Its Possible Reversal by Coapplication of Sulphate Open
The effect of selenate (Na2SeO4) and sulphate (Na2SO4) was studied on growth and metabolism in two rice cultivars cv. satabdi and cv. khitish. Selenate at low concentration (2 μM) expressed growth promoting effect on rice seedlings as oppo…
Silicon induced mitigation of TCA cycle and GABA synthesis in arsenic stressed wheat (Triticum aestivum L.) seedlings Open
The metalloid arsenic (As) is considered to be biologically non-essential and major environmental concern to all organisms. The aim of our study was to evaluate whether silicon (Si) has ameliorative effects on growth, respiratory cycle and…
Metabolomics analysis of <i>Cajanus cajan</i> L. seedlings unravelled amelioration of stress induced responses to salinity after halopriming of seeds Open
Soil salinity has become a major concern for agriculture. Such constraints not only reinforce the urgent need to understand the underlying mechanisms by which plants cope during salt stress but also to develop cost-effective and farmer fri…
POLYAMINES: ROLE IN ATTENUATION OF HEAVY METAL TOXICITY Open
Environmental changes resulted in a variety of stresses in plants of which heavy metal stress holds important position, affect the growth and development and trigger a series of morphological, physiological, biochemical and molecular chang…
SEED PRIMING: A MULTIFACETED AND COST-EFFECTIVE TECHNIQUE TO IMPROVE CROP PRODUCTION Open
Seed priming is a cost-effective technique which involves prior seed exposure to an abiotic stress that makes the seed more resistant to future lethal exposure. Seed priming stimulates pre-germination metabolic processes and makes the seed…
Regulation of Growth and Carbohydrate Metabolism in Rice (Oryza Sativa L.) seedlings by Selenium and Sulphate Open
Selenium is an essential and also toxic trace element for organisms including plants. We studied the role of selenium (Na2SeO4) on growth and carbohydrate metabolism and its interaction with sulphate (Na2SO4) in rice (Oryza sativa L. cv. S…
Emerging inflammatory dermatoses: New entities, novel observations, and concept review of selected established conditions Open
There has been relatively little change during the past four decades in the way dermatopathologists approach and interpret biopsies obtained from inflammatory skin disorders. If anything, there has been a stronger emphasis on clinicopathol…
Versatile Potentiality of Silicon in Mitigation of Biotic and Abiotic Stresses in Plants: A Review Open
The “quasi-essential element” silicon (Si) is not considered indispensable for plant growth and its accumulation varies between species largely due to differential uptake phenomena. Silicon uptake and distribution is a complex process invo…
Influence of Arsenate and Phosphate on the Regulation of Growth and TCA Cycle in the Rice (<i>Oryza sativa</i> L.) Cultivars IR64 and Nayanmani Open
The influence of arsenate and phosphate on the growth and respiration of 21 days old seedlings in two cultivars of rice, viz., IR64 and Nayanmani was studied. As arsenate and phosphate are similar in their chemical configuration and the la…
Amelioration of salinity stress by NaCl pretreatment with reference to sugar metabolism in legumes Cajanas cajan L. and Vigna mungo L. Open
The effect of salinity stress and its amelioration by pretreatment with low concentration of NaCl (50mM) on growth and sugar metabolism in arhar (cv. T120) and maskalai (cv. WBU109) seedlings were studied. Salinity was found to be more tox…
Selenium Modulates Growth and Thiol Metabolism in Wheat (<i>Triticum aestivum</i> L.) during Arsenic Stress Open
Arsenic affects plants by disrupting their growth and metabolism while selenium, an essential micronutrient has beneficial role in stress tolerance. Owing to the antioxidative capacity of selenium, it can counteract detrimental effects of …
Regulation of Growth, Antioxidants and Sugar Metabolism in Rice (<i>Oryza sativa</i> L.) Seedlings by NaCl and Its Reversal by Silicon Open
The effect of NaCl with or without silicon on the growth and metabolism in rice seedlings cv. MTU1010 was studied. In these seedlings, the oxidative stress has been observed with NaCl treatments and the levels of proline, H2O2 and malondia…