Dina Mansour
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View article: Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of oesophageal varices: study protocol for a randomised controlled trial
Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of oesophageal varices: study protocol for a randomised controlled trial Open
Background Liver disease is within the top five causes of premature death in adults. Deaths caused by complications of cirrhosis continue to rise, whilst deaths related to other non-liver disease areas are declining. Portal hypertension is…
View article: Biologic Therapy for Inflammatory Bowel Disease: Real-World Comparative Effectiveness and Impact of Drug Sequencing in 13 222 Patients within the UK IBD BioResource
Biologic Therapy for Inflammatory Bowel Disease: Real-World Comparative Effectiveness and Impact of Drug Sequencing in 13 222 Patients within the UK IBD BioResource Open
Background and Aims This study compares the effectiveness of different biologic therapies and sequences in patients with inflammatory bowel disease [IBD] using real-world data from a large cohort with long exposure. Methods Demographic, di…
View article: Role of Routine Hysteroscopy in Management of Women with Unexplained Infertility
Role of Routine Hysteroscopy in Management of Women with Unexplained Infertility Open
View article: Impact of Clomiphene Citrate, Tamoxifen and Letrozole in Women with Unexplained Infertility on Endometrial Thickness
Impact of Clomiphene Citrate, Tamoxifen and Letrozole in Women with Unexplained Infertility on Endometrial Thickness Open
Background: Polycystic ovarian syndrome (PCOS), which is characterized by irregular menstrual cycles, is the most common diagnosis given to affected women.For these women, ovulation induction is the usual course of therapy.Objective: To as…
View article: National study of NAFLD management identifies variation in delivery of care in the UK between 2019 to 2022
National study of NAFLD management identifies variation in delivery of care in the UK between 2019 to 2022 Open
View article: British Society of Gastroenterology Best Practice Guidance: outpatient management of cirrhosis – part 1: compensated cirrhosis
British Society of Gastroenterology Best Practice Guidance: outpatient management of cirrhosis – part 1: compensated cirrhosis Open
The prevalence of cirrhosis has risen significantly over recent decades and is predicted to rise further. Widespread use of non-invasive testing means cirrhosis is increasingly diagnosed at an earlier stage. Despite this, there are signifi…
View article: British Society of Gastroenterology Best Practice Guidance: outpatient management of cirrhosis – part 2: decompensated cirrhosis
British Society of Gastroenterology Best Practice Guidance: outpatient management of cirrhosis – part 2: decompensated cirrhosis Open
There are two distinct phases in the natural history of cirrhosis: compensated disease (corresponding to Child Pugh A and early Child Pugh B disease), where the patient may be largely asymptomatic, progressing with increasing portal hypert…
View article: British Society of Gastroenterology Best Practice Guidance: outpatient management of cirrhosis – part 3: special circumstances
British Society of Gastroenterology Best Practice Guidance: outpatient management of cirrhosis – part 3: special circumstances Open
The prevalence of cirrhosis has risen significantly over recent decades and is predicted to rise further. Widespread use of non-invasive testing means cirrhosis is increasingly diagnosed at an earlier stage. Despite this, there are signifi…
View article: Stratification Of LIver Disease (SOLID): protocol for a prospective observational cohort study to determine the optimum biomarker strategies for the detection of advanced liver disease at the primary–secondary care interface
Stratification Of LIver Disease (SOLID): protocol for a prospective observational cohort study to determine the optimum biomarker strategies for the detection of advanced liver disease at the primary–secondary care interface Open
Introduction Undiagnosed fatty liver disease is prevalent in the community, due to high rates of harmful alcohol consumption and/or obesity. Fatty liver disease can progress to cirrhosis and its complications. Early identification of liver…
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Editorial Board Open
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Editorial Board Open
View article: Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls Open
View article: Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group
Quality standards for the management of non-alcoholic fatty liver disease (NAFLD): consensus recommendations from the British Association for the Study of the Liver and British Society of Gastroenterology NAFLD Special Interest Group Open
Summary
\nNon-alcoholic fatty liver disease (NAFLD) is common, affecting approximately 25% of the general population. The evidence base for the investigation and management of NAFLD is large and growing, but there is currently little pract…
View article: Issue Information ‐ Editorial Board
Issue Information ‐ Editorial Board Open
The Americas), US$1,529 (Rest of World), €992 (Europe), £785 (UK
View article: Editorial Board
Editorial Board Open
View article: Identification of liver disease: why and how
Identification of liver disease: why and how Open
Mortality from chronic liver disease (CLD) in the UK has increased by over 400% since 1970, driven by alcohol, non-alcoholic fatty liver disease and hepatitis C virus, the natural histories of which can all be improved by early interventio…
View article: Improved outcomes following the implementation of a decompensated cirrhosis discharge bundle
Improved outcomes following the implementation of a decompensated cirrhosis discharge bundle Open
Introduction Mortality from liver disease is increasing and management of decompensated cirrhosis (DC) is inconsistent across the UK. Patients with DC have complex medical needs when discharged from hospital and early readmissions are comm…
View article: Embedding assessment of liver fibrosis into routine diabetic review in primary care
Embedding assessment of liver fibrosis into routine diabetic review in primary care Open
People with type 2 diabetes are at increased risk of developing non-alcoholic fatty liver disease and developing more significant complications. This study looks at introducing screening for advanced liver disease into the annual diabetes …
View article: Implementation of a care bundle improves the management of patients with non-alcoholic fatty liver disease
Implementation of a care bundle improves the management of patients with non-alcoholic fatty liver disease Open
Background Non-alcoholic fatty liver disease (NAFLD) is common and is associated with liver-related and cardiovascular-related morbidity. Our aims were: (1) to review the current management of patients with NAFLD attending hospital clinics…
View article: P199 Impact of a discharge proforma on the management of patients with decompensated liver disease
P199 Impact of a discharge proforma on the management of patients with decompensated liver disease Open
Objectives To produce and implement a discharge proforma, with the aim of improving record keeping and management of patients with decompensated cirrhosis. Decompensated liver disease is associated with a high mortality and can manifest in…
View article: EVALUATION OF OCULAR SURFACE CHANGES FOLLOWING LEVATOR RESECTION VS FRONTALIS SUSPENSION OPERATIONS
EVALUATION OF OCULAR SURFACE CHANGES FOLLOWING LEVATOR RESECTION VS FRONTALIS SUSPENSION OPERATIONS Open
Background: Blepharoptosis is abnormal low position of the upper eyelid The effect of ptosis surgery on ocular surface is not clear and needs more clarification. Aim of this Work: To compare between levator resection and frontalis sling op…
View article: Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients
Prognostic significance of DNMT3a gene expression and reactive nitrogen species in newly diagnosed Egyptian de novo adult acute myeloid leukemia patients Open
Background DNA methyltransferase 3a ( DNMT3a ) gene is a frequently dysregulated epigenetic modifier gene involved in the process of carcinogenesis. Also, there is a dichotomous nature of nitric oxide action with the ability to both promot…
View article: Incorporating assessment of liver fibrosis into routine diabetic review in primary care: a pilot
Incorporating assessment of liver fibrosis into routine diabetic review in primary care: a pilot Open
View article: The effect of misoprostol on intra-operative blood loss during myomectomy operation: Randomized controlled trial
The effect of misoprostol on intra-operative blood loss during myomectomy operation: Randomized controlled trial Open
Introduction: Uterine myomas are most prevalent benign tumors in reproductive-aged women. Myomectomy is a surgical treatment for symptomatic uterine myomas for women who want to preserve fertility. Uncontrolled intraoperative bleeding with…
View article: The Role of Time Zero Liver Biopsies Following Graft Reperfusion in Prediction of Early Graft Dysfunction in living Donor Liver Transplantation
The Role of Time Zero Liver Biopsies Following Graft Reperfusion in Prediction of Early Graft Dysfunction in living Donor Liver Transplantation Open
View article: PTH-097 Nafld: case-finding in diabetic patients from primary care using FIB4 score
PTH-097 Nafld: case-finding in diabetic patients from primary care using FIB4 score Open
Introduction In contrast to European guidelines, recent NICE and BSG guidelines state that further evidence is required to establish the cost-effectiveness of case-finding for non-alcoholic fatty liver disease (NAFLD) in high risk groups s…
View article: Management of decompensated cirrhosis
Management of decompensated cirrhosis Open
Decompensated cirrhosis is a common reason for admission to the acute medical unit, and such patients typically have complex medical needs and are at high risk of in-hospital death. It is therefore vital that these patients receive appropr…
View article: Evaluating the quality of life of adult patients on home parenteral nutrition in North East England and Cumbria
Evaluating the quality of life of adult patients on home parenteral nutrition in North East England and Cumbria Open