Ashwin Muraleetharan
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SCA44‐ and SCAR13‐associated <i>GRM1</i> mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms Open
Background and Purpose Metabotropic glutamate receptor 1 (mGlu 1 ) is a promising therapeutic target for neurodegenerative CNS disorders including spinocerebellar ataxias (SCAs). Clinical reports have identified naturally‐occurring mGlu 1 …
SCA44- and SCAR13-associated <i>GRM1</i> mutations affect metabotropic glutamate receptor 1 function through distinct mechanisms Open
Metabotropic glutamate receptor 1 (mGlu 1 ) is a promising therapeutic target for neurodegenerative CNS disorders including spinocerebellar ataxias (SCAs). Clinical reports have identified naturally-occurring mGlu 1 mutations in rare SCA s…