Asif Halimi
YOU?
Author Swipe
View article: Outcomes of surgery for borderline and locally advanced pancreatic cancer following neoadjuvant chemotherapy
Outcomes of surgery for borderline and locally advanced pancreatic cancer following neoadjuvant chemotherapy Open
Introduction Neoadjuvant chemotherapy (NAT) is standard treatment for borderline resectable (BRPC) and locally advanced pancreatic cancer (LAPC), aiming to shrink tumors, eliminate micrometastases, and assess tumor biology. However, not al…
View article: Development and validation of the SDLD score: a simplified tool to predict successful endoscopic papillectomy in ampullary lesions
Development and validation of the SDLD score: a simplified tool to predict successful endoscopic papillectomy in ampullary lesions Open
The SDLD score predicts R1 in EP and aids in treatment decisions.
View article: Patient-derived pancreatic tumor bacteria exhibit oncogenic properties and are recognized by MAIT cells in tumor spheroids
Patient-derived pancreatic tumor bacteria exhibit oncogenic properties and are recognized by MAIT cells in tumor spheroids Open
Introduction Tumor-residing microbiota poses a new challenge in cancer progression and therapy; however, the functional behavior of patient tumor-derived microbes remains poorly understood. We previously reported the presence of tumor micr…
View article: Tangential Versus Segmental Portomesenteric Venous Resection During Pancreatoduodenectomy for Pancreatic Cancer
Tangential Versus Segmental Portomesenteric Venous Resection During Pancreatoduodenectomy for Pancreatic Cancer Open
Objective: To investigate whether tangential versus segmental portomesenteric venous resection (PVR) impacts surgical and oncological outcome in patients undergoing pancreatoduodenectomy for pancreatic cancer with portomesenteric vein (PMV…
View article: Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis
Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis Open
Objective Ampullary neoplastic lesions can be resected by endoscopic papillectomy (EP) or transduodenal surgical ampullectomy (TSA) while pancreaticoduodenectomy is reserved for more advanced lesions. We present the largest retrospective c…
View article: Histological Subtypes Might Help Risk Stratification in Different Morphological Types of IPMNs: Back to the Future?
Histological Subtypes Might Help Risk Stratification in Different Morphological Types of IPMNs: Back to the Future? Open
Background: Intraductal papillary mucinous neoplasms (IPMNs) display four histological subtypes: gastric foveolar, pancreaticobiliary, intestinal, and oncocytic. All of these subtypes harbor a different risk of cancer development. The clin…
View article: Surveillance after surgery for pancreatic cancer: a global scoping review of guidelines and a nordic Survey of contemporary practice
Surveillance after surgery for pancreatic cancer: a global scoping review of guidelines and a nordic Survey of contemporary practice Open
Evidence for routine long-term (i.e. 5 years) surveillance after pancreatic cancer surgery remains limited. Most pancreatic units in the Nordic countries conduct regular follow-up, but protocols vary.
View article: Interactions between the Exocrine and the Endocrine Pancreas
Interactions between the Exocrine and the Endocrine Pancreas Open
The pancreas has two main functions: to produce and secrete digestive enzymes (exocrine function) and to produce hormones that regulate blood glucose and splanchnic secretion (endocrine function). The endocrine and exocrine portions of the…
View article: Outcome after total pancreatectomy with islet autotransplantation: A European single-center study
Outcome after total pancreatectomy with islet autotransplantation: A European single-center study Open
Background and aims: Chronic pancreatitis may cause intractable abdominal pain, with total pancreatectomy sometimes being the last resort. To mitigate the subsequent diabetes, total pancreatectomy can be followed by islet autotransplantati…
View article: Isolation of pancreatic microbiota from cystic precursors of pancreatic cancer with intracellular growth and DNA damaging properties
Isolation of pancreatic microbiota from cystic precursors of pancreatic cancer with intracellular growth and DNA damaging properties Open
Emerging research suggests gut microbiome may play a role in pancreatic cancer initiation and progression, but cultivation of the cancer microbiome remains challenging. This pilot study aims to investigate the possibility to cultivate panc…
View article: Clinical Outcomes After Total Pancreatectomy
Clinical Outcomes After Total Pancreatectomy Open
Objective: To assess outcomes among patients undergoing total pancreatectomy (TP) including predictors for complications and in-hospital mortality. Background: Current studies on TP mostly originate from high-volume centers and span long t…
View article: Metabolic characterization of plasma and cyst fluid from cystic precursors to pancreatic cancer patients reveal metabolic signatures of bacterial infection
Metabolic characterization of plasma and cyst fluid from cystic precursors to pancreatic cancer patients reveal metabolic signatures of bacterial infection Open
Pancreatic cancer is the seventh leading cause of cancer-related death worldwide, with a 5-year survival rate as low as 9%. One factor complicating the management of pancreatic cancer is the lack of reliable tools for early diagnosis. Whil…
View article: Evaluation of Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After Neoadjuvant FOLFIRINOX Treatment
Evaluation of Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After Neoadjuvant FOLFIRINOX Treatment Open
These results suggest that adjuvant chemotherapy after neoadjuvant FOLFIRINOX and resection of pancreatic cancer was associated with improved survival only in patients with pathology-proven node-positive disease. Future randomized studies …
View article: Circulating and Salivary Antibodies to Fusobacterium nucleatum Are Associated With Cystic Pancreatic Neoplasm Malignancy
Circulating and Salivary Antibodies to Fusobacterium nucleatum Are Associated With Cystic Pancreatic Neoplasm Malignancy Open
OBJECTIVES: Intraductal papillary mucinous neoplasms (IPMNs) are cystic precursor lesions to pancreatic cancer. The presence of oral microbes in pancreatic tissue or cyst fluid has been associated with high-grade dysplasia (HGD) and cancer…
View article: Gemcitabine-based adjuvant chemotherapy in subtypes of ampullary adenocarcinoma: international propensity score-matched cohort study
Gemcitabine-based adjuvant chemotherapy in subtypes of ampullary adenocarcinoma: international propensity score-matched cohort study Open
Background Whether patients who undergo resection of ampullary adenocarcinoma have a survival benefit from adjuvant chemotherapy is currently unknown. The aim of this study was to compare survival between patients with and without adjuvant…
View article: In the Era of the Leeds Protocol: A Systematic Review and A Meta-Analysis on the Effect of Resection Margins on Survival Among Pancreatic Ductal Adenocarcinoma Patients
In the Era of the Leeds Protocol: A Systematic Review and A Meta-Analysis on the Effect of Resection Margins on Survival Among Pancreatic Ductal Adenocarcinoma Patients Open
Background and Aims: A positive resection margin is considered to be a factor associated with poor prognosis after pancreatic ductal adenocarcinoma resection. However, analysis of the resection margin is dependent on the pathological slici…
View article: Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer
Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer Open
Objectives Intraductal papillary mucinous neoplasms (IPMNs) are pancreatic cysts that can progress to invasive pancreatic cancer. Associations between oncogenesis and oral microbiome alterations have been reported. This study aims to inves…
View article: AB019. S019. Pancreatectomy plus arterial resection is superior to palliation in patients with locally advanced PDAC
AB019. S019. Pancreatectomy plus arterial resection is superior to palliation in patients with locally advanced PDAC Open
Background: Pancreatectomy plus arterial resection (PAR) for locally advanced pancreatic ductal adenocarcinoma (PDAC) (LAPC) might potentially offer additional therapeutic option and a better prognosis in patients traditionally addressed t…
View article: AB008. S008. Diagnostic yield of intraoperative pancreatoscopy for the investigation of pancreatic IPMN
AB008. S008. Diagnostic yield of intraoperative pancreatoscopy for the investigation of pancreatic IPMN Open
Background: Intraoperative pancreatoscopy in a very promising tool that might, in the future, guide surgical resection during surgery for intraductal papillary mucinous neoplasm (IPMN). Nevertheless data about diagnostic yield are still la…