Asiyeh Sadat Zahedi
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View article: Within-family analysis of PRS313: insights into breast cancer risk prediction
Within-family analysis of PRS313: insights into breast cancer risk prediction Open
View article: Tracking the correlation of mineral intakes among family pairs over nine years: a longitudinal study
Tracking the correlation of mineral intakes among family pairs over nine years: a longitudinal study Open
Our study revealed a decreasing trend in correlation or regression towards the mean over time for most minerals in family pairs.
View article: The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes
The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes Open
View article: Examining the clinical and genetic spectrum of maturity-onset diabetes of the young (MODY) in Iran
Examining the clinical and genetic spectrum of maturity-onset diabetes of the young (MODY) in Iran Open
View article: The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes
The effect of family structure on the still-missing heritability and genomic prediction accuracy of type 2 diabetes Open
This study aims to assess the effect of familial structures on the still-missing heritability estimate and prediction accuracy of Type 2 Diabetes (T2D) using pedigree estimated risk values (ERV) and genomic ERV. We used 11,818 individuals …
View article: Three candidate SNPs show associations with thyroid-stimulating hormone in euthyroid subjects: Tehran thyroid study
Three candidate SNPs show associations with thyroid-stimulating hormone in euthyroid subjects: Tehran thyroid study Open
View article: Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population
Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population Open
View article: Familial resemblance and family-based heritability of nutrients intake in Iranian population: Tehran cardiometabolic genetic study
Familial resemblance and family-based heritability of nutrients intake in Iranian population: Tehran cardiometabolic genetic study Open
View article: Association of baseline and changes in adiponectin, homocysteine, high-sensitivity C-reactive protein, interleukin-6, and interleukin-10 levels and metabolic syndrome incidence: Tehran lipid and glucose study
Association of baseline and changes in adiponectin, homocysteine, high-sensitivity C-reactive protein, interleukin-6, and interleukin-10 levels and metabolic syndrome incidence: Tehran lipid and glucose study Open
After a six-year average follow-up, hs-CRP and IL-6 levels were deemed more reliable predictors of MetS incidence and persistence, respectively.
View article: Regularized Machine Learning Models for Prediction of Metabolic Syndrome Using <i>GCKR, APOA5,</i> and <i>BUD13</i> Gene Variants: Tehran Cardiometabolic Genetic Study.
Regularized Machine Learning Models for Prediction of Metabolic Syndrome Using <i>GCKR, APOA5,</i> and <i>BUD13</i> Gene Variants: Tehran Cardiometabolic Genetic Study. Open
Regularized machine learning models provided more accurate and parsimonious MetS classifying models. These high-performing diagnostic models can lay the foundation for clinical decision support tools that use genetic and demographical vari…
View article: Evidence of familial resemblance and family-based heritability of food intakes derived from a longitudinal cohort study
Evidence of familial resemblance and family-based heritability of food intakes derived from a longitudinal cohort study Open
We sought to investigate the familial aggregation and family-based heritability of dietary intakes among adults in a population-based longitudinal study of the Tehran Lipid and Glucose Study (TLSG). Total of 4359 males and 5439 females ent…
View article: Correction: GCKR common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults
Correction: GCKR common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults Open
View article: Cohort profile update: Tehran cardiometabolic genetic study
Cohort profile update: Tehran cardiometabolic genetic study Open
View article: Resemblance of nutrient intakes in three generations of parent-offspring pairs: Tehran lipid and Glucose Study
Resemblance of nutrient intakes in three generations of parent-offspring pairs: Tehran lipid and Glucose Study Open
The degree of maintaining nutrient intake patterns, conformed in the family, for offspring into adulthood is unknown. The aim of this study was to investigate the correlation between nutrient intakes in three younger-middle-older generatio…
View article: Sex, age, and ethnic dependency of lipoprotein variants as the risk factors of ischemic heart disease: a detailed study on the different age-classes and genders in Tehran Cardiometabolic Genetic Study (TCGS)
Sex, age, and ethnic dependency of lipoprotein variants as the risk factors of ischemic heart disease: a detailed study on the different age-classes and genders in Tehran Cardiometabolic Genetic Study (TCGS) Open
View article: Familial genetic and environmental risk profile and high blood pressure event: a prospective cohort of cardio-metabolic and genetic study
Familial genetic and environmental risk profile and high blood pressure event: a prospective cohort of cardio-metabolic and genetic study Open
Findings from this study show that familial genetic and environmental risk profile increase risk for high blood pressure beyond the effect of the individuals' own risk factors.
View article: GCKR common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults
GCKR common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults Open
View article: GCKR Common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults
GCKR Common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults Open
Background: Previous studies reported that common functional variants (rs780093, rs780094, and rs1260326) in the glucokinase regulator gene ( GCKR ) were associated with metabolic syndrome despite the simultaneous association with the favo…
View article: TCF7L2 polymorphisms, nut consumption, and the risk of metabolic syndrome: a prospective population based study
TCF7L2 polymorphisms, nut consumption, and the risk of metabolic syndrome: a prospective population based study Open
View article: GCKR Common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults
GCKR Common functional polymorphisms are associated with metabolic syndrome and its components: a 10-year retrospective cohort study in Iranian adults Open
Background Previous studies reported that common functional variants (rs780093, rs780094, and rs1260326) in the glucokinase regulator gene ( GCKR ) were associated with metabolic syndrome despite the simultaneous association with the favor…
View article: Familial genetic and environmental risk profile and high blood pressure event: a prospective cohort of cardio-metabolic and genetic study
Familial genetic and environmental risk profile and high blood pressure event: a prospective cohort of cardio-metabolic and genetic study Open
High blood pressure is the heritable risk factor for cardiovascular diseases. We investigated whether the presence of familial genetic and environmental risk factors are associated with increased risk of high blood pressure. A total of 4,5…
View article: GCKR Common Functional Polymorphisms are Associated with Metabolic Syndrome and its Components: A 10-Year Retrospective Cohort Study in Iranian Adults
GCKR Common Functional Polymorphisms are Associated with Metabolic Syndrome and its Components: A 10-Year Retrospective Cohort Study in Iranian Adults Open
Background: Some previous studies reported that common functional variants (rs780093, rs780094, and rs1260326) in the glucokinase regulator gene ( GCKR ) were associated with metabolic syndrome despite the simultaneous association with the…
View article: High genetic burden of type 2 diabetes can promote the high prevalence of disease: a longitudinal cohort study in Iran
High genetic burden of type 2 diabetes can promote the high prevalence of disease: a longitudinal cohort study in Iran Open
View article: Associations of common polymorphisms in GCKR with metabolic syndrome
Associations of common polymorphisms in GCKR with metabolic syndrome Open
Background: Metabolic syndrome (MetS) is characterized by a combination of cardio-metabolic risk factors. Given that genetic factors have been shown to contribute to individual susceptibility to MetS, the identification of genetic markers …