Asmaa Mohamed
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View article: Pre-conditioning radiation synergizes with IL2-superkine (Sup2) and IL33 armed CAR T cells to control solid tumor growth through increased CAR T cell engraftment and persistent effector activity 3584
Pre-conditioning radiation synergizes with IL2-superkine (Sup2) and IL33 armed CAR T cells to control solid tumor growth through increased CAR T cell engraftment and persistent effector activity 3584 Open
Description Chimeric antigen receptor (CAR) T cells are highly effective against liquid tumors but have limited efficacy against solid tumors. We previously showed that melanoma-specific CAR T cells armed with IL2 superkine (Sup2) and alar…
View article: Xanthogranulomatous Epithelial Tumor: A Case Report With 1‐Year Follow‐Up
Xanthogranulomatous Epithelial Tumor: A Case Report With 1‐Year Follow‐Up Open
SummaryXanthogranulomatous epithelial tumor (XGET) is a rare soft tissue and bone neoplasm with distinct immunophenotypic and molecular features.The banal histomorphological characteristics of this lesion fail to foreshadow its potentially…
View article: Depletion of conventional CD4<sup>+</sup> T cells is required for robust priming and dissemination of tumor antigen-specific CD8<sup>+</sup> T cells in the setting of anti-CD4 therapy
Depletion of conventional CD4<sup>+</sup> T cells is required for robust priming and dissemination of tumor antigen-specific CD8<sup>+</sup> T cells in the setting of anti-CD4 therapy Open
Background Overcoming immune suppression is a major barrier to eliciting potent CD8 + T cell responses against cancer. Treatment with anti-CD4 monoclonal antibody is an effective means for eliminating CD4 + Foxp3 + regulatory (Treg) cells …
View article: Accuracy of an internationally validated genetic-guided warfarin dosing algorithm compared to a clinical algorithm in an Arab population
Accuracy of an internationally validated genetic-guided warfarin dosing algorithm compared to a clinical algorithm in an Arab population Open
CYP2C9 and VKORC1 variants are important determinants of warfarin dose in the Arab population. The use of the genetic and clinical factors led to better warfarin dose estimation when compared to clinical factors alone.
View article: "Effect of Clinical Pathway Implementation on Sequential Organ Failure Assessment Score and (Pain, Inspiration, and Cough) Score for Chest Trauma Patients”
"Effect of Clinical Pathway Implementation on Sequential Organ Failure Assessment Score and (Pain, Inspiration, and Cough) Score for Chest Trauma Patients” Open
View article: Urtica pilulifera leaves exacerbate the cisplatin effect in Ehrlich ascites carcinoma-bearing mice
Urtica pilulifera leaves exacerbate the cisplatin effect in Ehrlich ascites carcinoma-bearing mice Open
Conventional chemotherapy is an effective approach to cancer treatment. However, several side effects limited its uses. Natural products have been reported for their anticancer potential. This study evaluated the anticancer efficacy of Urt…
View article: CD4 depletion enhances the efficacy of Super2 IL-33 armored CAR T cell against solid tumors and leads memory formation of both endogenous and CAR T cells
CD4 depletion enhances the efficacy of Super2 IL-33 armored CAR T cell against solid tumors and leads memory formation of both endogenous and CAR T cells Open
Chimeric antigen receptor (CAR) T cells exhibit tremendous efficacy in patients with relapsed and recurrent liquid cancers. However, CAR T cells fail to control solid tumors because of their inability to infiltrate the suppressive tumor en…
View article: Factors Affecting Performance of Cardiopulmonary Resuscitation Team
Factors Affecting Performance of Cardiopulmonary Resuscitation Team Open
View article: The Relationship between Serum Sclerostin Levels and Bone Mineral Disorders and Vascular Calcification in Hemodialysis Patients
The Relationship between Serum Sclerostin Levels and Bone Mineral Disorders and Vascular Calcification in Hemodialysis Patients Open
Background and aim of the study: Sclerostin is produced by osteocytes and has been shown to down-regulate the synthesis of many markers of bone formation by osteogenic cells. The aim of this study to investigate the relationship between se…
View article: Effect of Self-Care Guidelines on Symptoms Burden for Patients with Lung Cancer Undergoing Chemotherapy
Effect of Self-Care Guidelines on Symptoms Burden for Patients with Lung Cancer Undergoing Chemotherapy Open
Context: Lung cancer is common cancer worldwide. Because of the high-symptoms burden and severe morbidity, effective symptoms management requires comprehensive self-care strategies.
Aim: This study was aimed to assess the effect of self-c…
View article: Effect of Self-Care Guidelines on Chemotherapy Associated Symptoms for patients with lung Cancer
Effect of Self-Care Guidelines on Chemotherapy Associated Symptoms for patients with lung Cancer Open
Background; Lung cancer is common cancers worldwide.In view of the highsymptoms burden and sever morbidity, Effective symptoms management requires comprehensive self -care strategies Aim: of this study was to evaluate the effect of self-ca…
View article: Impact of Applying Dietary Pattern on Nutritional Status of Patients with Leukemia Undergoing Chemotherapy
Impact of Applying Dietary Pattern on Nutritional Status of Patients with Leukemia Undergoing Chemotherapy Open
Leukemia is common neoplastic disease accounting 40-55% worldwide.Malnutrition in cancer patients has been reported occurrence 36% of patients in USA and in 50 % of patients in Netherlands.Patients' nutritional needs must include energy re…
View article: Nursing Intervention for Caregivers of Post Autologous Bone Marrow Transplantation Patients at Home
Nursing Intervention for Caregivers of Post Autologous Bone Marrow Transplantation Patients at Home Open
Background: Autologous bone marrow transplantation is a curative procedure for hematological diseasesand immune deficiencies. The unique and intensive nature of this treatment requires distinctive care duringand post the entire transplant …
View article: Sclerostin depletion induces inflammation in the bone marrow of mice
Sclerostin depletion induces inflammation in the bone marrow of mice Open
Romosozumab, a humanized monoclonal antibody specific for sclerostin, has been approved for treatment of post-menopausal women with osteoporosis at high risk for fracture. In several Phase III clinical trials, romosozumab decreased the ris…
View article: Factors Affecting Post Open-Heart Surgery Outcomes for Hospitalized patients
Factors Affecting Post Open-Heart Surgery Outcomes for Hospitalized patients Open
Background: Open heart surgery plays an important role in the management of
cardiovascular diseases. A number of preoperative predictive factors for complicated Intensive
Care Unit (ICU) stay were identified. Postoperative outcomes are d…
View article: Factors Affecting Central Venous Catheter’s Dwell Time in Critically Ill Patients: Suggested Guideline
Factors Affecting Central Venous Catheter’s Dwell Time in Critically Ill Patients: Suggested Guideline Open
Background: Central venous catheter (CVC) is a hollow tube that provides reliable vascular access in critically ill patients. The dwell time of the catheter is ample, limited by presence of complications-related factors. Nursing care regar…
View article: Factors Affecting Nurses’ Performance Regarding Use of Physical Restraints in Critical Care Unit
Factors Affecting Nurses’ Performance Regarding Use of Physical Restraints in Critical Care Unit Open
Background: Physical restraints are any devices or materials attached to patients’ bodyprevent the patient from pulling the connected devices. Aim: assess factors affecting nurses’ performance regarding use of physical restraint in critica…
View article: EVALUATION IMPACT OF THE ECONOMIC COSTS OF MALNUTRITION DISEASES OF EGYPT’S SUSTAINABLE DEVELOPMENT
EVALUATION IMPACT OF THE ECONOMIC COSTS OF MALNUTRITION DISEASES OF EGYPT’S SUSTAINABLE DEVELOPMENT Open
The study aims to refer to one of the major problems that impedes sustainable development, as well as to clarify the additional costs resulting from malnutrition and the extent to which it affects economic growth. The analytical descriptiv…
View article: Ozone Preconditioning Attenuates Spinal Cord Ischemia/ Reperfusion Injury in Rats
Ozone Preconditioning Attenuates Spinal Cord Ischemia/ Reperfusion Injury in Rats Open
Spinal cord ischemia/reperfusion injury (SC-IRI) can result in paraplegia. In this study, we investigated the protective effect of medical ozone on SC-IRI. To investigate this, 40 rats were divided into five equal groups: the control (n=8)…
View article: Evaluating Nursing Students’ Perception toward Use of E-Portfolio as an Innovative Learning Strategy for Student Assessment
Evaluating Nursing Students’ Perception toward Use of E-Portfolio as an Innovative Learning Strategy for Student Assessment Open
Portfolios have been advocated in nursing education to help student link theory and practice. E-portfolio has the advantage of allowing students to record, assess, and reflect upon their learning. Aim: This study aimed to evaluate nursing …
View article: Effect of care protocol on the knowledge, practice and clinical outcomes of patients with chronic obstructive pulmonary disease
Effect of care protocol on the knowledge, practice and clinical outcomes of patients with chronic obstructive pulmonary disease Open
Background : Care protocol for patients with chronic obstructive pulmonary disease is considered as a strategy for promoting their knowledge, practice and clinical outcomes. Aim: This study aimed to evaluate the effect of care protocol on …
View article: Effect of Educational Nursing Intervention on Knowledge and Practices of Patients with Implantable Port Catheter and Undergoing Chemotherapy
Effect of Educational Nursing Intervention on Knowledge and Practices of Patients with Implantable Port Catheter and Undergoing Chemotherapy Open