Assem M. Khamis
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View article: Symptom prevalence in gastrointestinal cancer: a secondary analysis of IPOS data
Symptom prevalence in gastrointestinal cancer: a secondary analysis of IPOS data Open
Purpose Patients with gastro-intestinal (GI) cancer have a high symptom burden; however, comparative data to other cancers is lacking. The aim is to determine symptom prevalence for people with GI cancer receiving specialist palliative car…
View article: Capturing the influx of living systematic reviews: a systematic methodological survey
Capturing the influx of living systematic reviews: a systematic methodological survey Open
Every year, a huge amount of health-related research is published and it is difficult for busy doctors and health care workers to keep up to date with all of the new evidence. To help with this, the research can be summarized by carrying o…
View article: Human Platelet Alloantigen 1 and 2 Genes Polymorphisms and Coronary Artery Disease Severity
Human Platelet Alloantigen 1 and 2 Genes Polymorphisms and Coronary Artery Disease Severity Open
View article: Pattern and Frequency of Congenital Heart Defects Among Infants of Diabetic Mothers
Pattern and Frequency of Congenital Heart Defects Among Infants of Diabetic Mothers Open
View article: Patterns of acute hospital and specialist palliative care use among people with non-curative upper gastrointestinal cancer
Patterns of acute hospital and specialist palliative care use among people with non-curative upper gastrointestinal cancer Open
View article: Patterns of acute hospital and specialist palliative care use among people with non-curative upper gastrointestinal cancer.
Patterns of acute hospital and specialist palliative care use among people with non-curative upper gastrointestinal cancer. Open
Purpose: Upper gastrointestinal (GI) cancers contribute to 16.7% of United Kingdom cancer deaths. These patients make high use of acute hospital services, but detail about palliative care use is lacking. We aimed to determine the patterns …
View article: Contraception Use Among Muslim Women in Alexandria, Egypt - a Descriptive Pilot Study
Contraception Use Among Muslim Women in Alexandria, Egypt - a Descriptive Pilot Study Open
This pilot project explored knowledge, attitudes and practices related to contraception in Alexandria, Egypt using questionnaire assisted interviews. The goal of the study was to test and validate the survey instrument for a larger scale s…
View article: Supplementary Material for: Endovascular thrombectomy with or without bridging thrombolysis in acute ischemic stroke: A cost-effectiveness analysis
Supplementary Material for: Endovascular thrombectomy with or without bridging thrombolysis in acute ischemic stroke: A cost-effectiveness analysis Open
Background There is unclear added benefit of intravenous thrombolysis (IVT) with endovascular thrombectomy (EVT). We performed a cost-effectiveness analysis to assess the cost-effectiveness comparing EVT with IVT versus EVT alone. Methods …
View article: Endovascular Thrombectomy with or without Bridging Thrombolysis in Acute Ischemic Stroke: A Cost-Effectiveness Analysis
Endovascular Thrombectomy with or without Bridging Thrombolysis in Acute Ischemic Stroke: A Cost-Effectiveness Analysis Open
Background: There is unclear added benefit of intravenous thrombolysis (IVT) with endovascular thrombectomy (EVT). We performed a cost-effectiveness analysis to assess the cost-effectiveness of comparing EVT with IVT versus E…
View article: Association between human chorionic gonadotropin (hCG) levels and adverse pregnancy outcomes: A systematic review and meta-analysis
Association between human chorionic gonadotropin (hCG) levels and adverse pregnancy outcomes: A systematic review and meta-analysis Open
Human chorionic gonadotropin (hCG), a glycoprotein produced in the placenta, is crucial for a healthy pregnancy. We investigated the relationship between hCG levels and adverse pregnancy outcomes. We conducted a systematic review including…
View article: Endovascular Thrombectomy With or Without Thrombolysis for Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Endovascular Thrombectomy With or Without Thrombolysis for Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
Background To this date, whether to administer intravenous thrombolysis (IVT) prior to endovascular thrombectomy (EVT) for stroke patients still stirs some debate. We aimed to systematically update the evidence from randomized trials compa…
View article: O28/275 Cost utility analysis of bridging intravenous thrombolysis with endovascular thrombectomy
O28/275 Cost utility analysis of bridging intravenous thrombolysis with endovascular thrombectomy Open
Introduction Clinical equipoise exists behind bridging intravenous thrombolysis (BT) with endovascular thrombectomy (EVT). Aim of Study To compare the cost-effectiveness of EVT alone vs. BT in acute ischemic stroke (AIS) Methods We conduct…
View article: P170/281 Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischemic stroke: a systematic review and meta-analysis of randomized trials
P170/281 Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischemic stroke: a systematic review and meta-analysis of randomized trials Open
Introduction An updated analysis comparing endovascular thrombectomy (EVT) alone versus endovascular therapy without bridging intravenous thrombolysis (IVT) has not been performed. Aim of Study To systematically update the evidence from ra…
View article: P-010 Endovascular thrombectomy with or without bridging thrombolysis in acute ischemic stroke: a cost-effectiveness analysis
P-010 Endovascular thrombectomy with or without bridging thrombolysis in acute ischemic stroke: a cost-effectiveness analysis Open
Background There is unclear added benefit of intravenous thrombolysis (IVT) with endovascular thrombectomy (EVT). We performed a cost-effectiveness analysis to assess the cost-effectiveness comparing EVT with IVT versus EVT alone. Methods …
View article: Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischaemic stroke: protocol for a systematic review, meta-analysis of randomised trials and cost-effectiveness analysis
Endovascular thrombectomy with or without thrombolysis bridging in patients with acute ischaemic stroke: protocol for a systematic review, meta-analysis of randomised trials and cost-effectiveness analysis Open
Introduction Current published guidelines and meta-analyses comparing endovascular thrombectomy (EVT) alone versus EVT with bridging intravenous thrombolysis (IVT) suggest that EVT alone is non-inferior to EVT with bridging thrombolysis in…
View article: Abstract Number ‐ 176: Mechanical thrombectomy with or without bridging in stroke: A systematic review and meta‐analysis of RCTs
Abstract Number ‐ 176: Mechanical thrombectomy with or without bridging in stroke: A systematic review and meta‐analysis of RCTs Open
Introduction Current published guidelines and meta‐analyses comparing direct mechanical thrombectomy (MT) alone versus MT with bridging intravenous thrombolysis (IVT) suggested that MT alone is non‐inferior to MT with bridging thrombolysis…
View article: Abstract Number ‐ 24: Endovascular thrombectomy with or without bridging thrombolysis in patients with ischemic stroke: A cost‐utility analysis
Abstract Number ‐ 24: Endovascular thrombectomy with or without bridging thrombolysis in patients with ischemic stroke: A cost‐utility analysis Open
Introduction There is clinical equipoise behind bridging intravenous thrombolysis (BT) with endovascular thrombectomy (EVT). We performed a cost‐effectiveness analysis comparing EVT and BT versus EVT alone. Methods We conducted a model‐bas…
View article: Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary disease (COPD)
Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary disease (COPD) Open
IMT may not improve dyspnea, functional exercise capacity and life quality when associated with PR. However, IMT is likely to improve these outcomes when provided alone. For both interventions, a larger effect in participants with respirat…
View article: A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty
A non-randomised controlled study to assess the effectiveness of a new proactive multidisciplinary care intervention for older people living with frailty Open
Background Integrated care may improve outcomes for older people living with frailty. We aimed to assess the effectiveness of a new, anticipatory, multidisciplinary care service in improving the wellbeing and quality of life (QoL) of older…
View article: 1195 EFFECTIVENESS OF A NEW PROACTIVE MULTIDISCIPLINARY CARE SERVICE FOR OLDER PEOPLE WITH FRAILTY: A NON-RANDOMISED CONTROLLED TRIAL
1195 EFFECTIVENESS OF A NEW PROACTIVE MULTIDISCIPLINARY CARE SERVICE FOR OLDER PEOPLE WITH FRAILTY: A NON-RANDOMISED CONTROLLED TRIAL Open
Introduction Integrated care potentially improves health outcomes for older people with frailty. We aimed to assess the effectiveness of a new, proactive, multidisciplinary care service in improving the wellbeing and quality-of-life of old…
View article: Abdominal Visceral Adipose Tissue and All-Cause Mortality: A Systematic Review
Abdominal Visceral Adipose Tissue and All-Cause Mortality: A Systematic Review Open
Introduction Increased abdominal visceral adipose tissue (VAT) implies an adverse cardio-metabolic profile. We examined the association of abdominal VAT parameters and all-cause mortality risk. Methods We systematically searched four datab…
View article: Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis
Long Term Weight Loss Diets and Obesity Indices: Results of a Network Meta-Analysis Open
Background Scientists have been investigating efficient interventions to prevent and manage obesity. This network meta-analysis (NMA) compared the effect of different diets [moderate macronutrients (MMs), low fat/high carbohydrate (LFHC), …
View article: Contraception use among Muslim women in Alexandria, Egypt: a descriptive pilot study
Contraception use among Muslim women in Alexandria, Egypt: a descriptive pilot study Open
Background: This pilot study aimed to create a questionnaire survey directed to understand knowledge gaps related to contraception among Muslim women in Alexandria, Egypt, so potential interventions could be designed to enable more informe…
View article: Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials
Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials Open
Background To summarise specific adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir in patients with COVID-19. Methods We searched 32 databases through 27 October 2020. We included randomised trials comparing any of …
View article: Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19: systematic review and network meta-analysis
Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19: systematic review and network meta-analysis Open
Objective To compare the effects of interleukin 6 receptor blockers, tocilizumab and sarilumab, with or without corticosteroids, on mortality in patients with covid-19. Design Systematic review and network meta-analysis. Data sources World…
View article: Tailored PRISMA 2020 flow diagrams for living systematic reviews: a methodological survey and a proposal
Tailored PRISMA 2020 flow diagrams for living systematic reviews: a methodological survey and a proposal Open
Background: While the PRISMA flow diagram is widely used for reporting standard systematic reviews (SRs), it was not designed for capturing the results of continual searches for studies in living systematic reviews (LSRs). The objectives o…
View article: Concurrent Validity and Prognostic Utility of the Needs Assessment Tool: Progressive Disease Heart Failure
Concurrent Validity and Prognostic Utility of the Needs Assessment Tool: Progressive Disease Heart Failure Open
View article: ROB2_IRPG_beta_v7_IMT_COP.xlsm
ROB2_IRPG_beta_v7_IMT_COP.xlsm Open
This is our risk of bias assessment using the ROB 2.0 tool for our Cochrane systematic review: inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary disease.
View article: Abdominal Visceral Adipose Tissue and All-Cause Mortality: A Systematic Review
Abdominal Visceral Adipose Tissue and All-Cause Mortality: A Systematic Review Open
Introduction Increased abdominal visceral adipose tissue (VAT) implies an adverse cardio-metabolic profile. We examined the association of abdominal VAT parameters and all-cause mortality risk. Methods We systematically searched four datab…
View article: ROB2_IRPG_beta_v7_IMT_COP.xlsm
ROB2_IRPG_beta_v7_IMT_COP.xlsm Open
This is our risk of bias assessment using the ROB 2.0 tool for our Cochrane systematic review: inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary disease.