Astrid J.F. Thielen
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View article: 3D Quantification of Viral Transduction Efficiency in Living Human Retinal Organoids
3D Quantification of Viral Transduction Efficiency in Living Human Retinal Organoids Open
The development of therapeutics builds on testing their efficiency in vitro. To optimize gene therapies, for example, fluorescent reporters expressed by treated cells are typically utilized as readouts. Traditionally, their global fluoresc…
View article: The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation Open
Objectives The complement system is an important component of innate immunity. The alternative pathway (AP) amplification loop is considered an essential feed forward mechanism for complement activation. However, the role of the AP in clas…
View article: Regulation of complement activation on red blood cells
Regulation of complement activation on red blood cells Open
The complement system is a crucial part of our innate immune system and is important as first line of defense against pathogens. Next to pathogen clearance, the complement system also plays an important role in removing damaged or dying ce…
View article: Editorial Board / Contents / Imprint
Editorial Board / Contents / Imprint Open
View article: Meetings and Conferences
Meetings and Conferences Open
View article: Acknowledgement to Reviewers
Acknowledgement to Reviewers Open
View article: Society Bulletins
Society Bulletins Open
View article: Complement Deposition and IgG Binding on Stored Red Blood Cells Are Independent of Storage Time
Complement Deposition and IgG Binding on Stored Red Blood Cells Are Independent of Storage Time Open
Background: In the Netherlands, red blood cells (RBCs) are allowed to be stored up to 35 days at 2-6 °C in saline-adenine-glucose-mannitol (SAGM). During storage, RBCs undergo several changes that are collectively known as storage l…
View article: Contents Vol. 45, 2018
Contents Vol. 45, 2018 Open
View article: Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice
Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice Open