Athanasios K. Petridis
YOU?
Author Swipe
Report of the First Completed On-site Vascular Neurosurgery Fellowship Program in Cameroon Open
Background and Aim: Vascular neurosurgical expertise is highly in demand in African countries.To create a sustainable environment for treating the patients, local neurosurgeons have tobe trained and be able to operate under the local circu…
Clinical management of a ruptured intracranial aneurysm Open
Background Intracranial hemorrhage due to a ruptured aneurysm is one of the most serious neurosurgical emergencies. The patient mostly presents with severe headaches and neurological deterioration. A rapid diagnosis and an interdisciplinar…
Interdisciplinary Therapeutic Approaches to Atypical and Malignant Meningiomas Open
Meningiomas have the highest incidence among brain tumors. In contrast to benign tumors that constitute the majority of this tumor entity, the treatment of aggressive meningiomas (WHO Grade 2 and 3) is more challenging, requiring gross tot…
Extradural lumbar arteriovenous fistula imitating a synovial cyst: illustrative case Open
BACKGROUND Spinal dural arteriovenous fistula is the most common spinal vascular malformation. It usually presents with neurological deficits due to venous congestive myelopathy. Sometimes, however, the symptoms are radicular and can imita…
Traumatic carotid cavernous fistulas. Rare and life threatening Open
A carotid-cavernous fistula presenting with a red swollen eye can be misdiagnosed as retrobulbar hematoma or conjunctivitis. Failure to recognize and treat it promptly can lead to severe morbidity.
Blood pH Analysis in Combination with Molecular Medical Tools in Relation to COVID-19 Symptoms Open
The global outbreak of SARS-CoV-2/COVID-19 provided the stage to accumulate an enormous biomedical data set and an opportunity as well as a challenge to test new concepts and strategies to combat the pandemic. New research and molecular me…
Association of aneurysmatic subarachnoid hemorrhage rate with environmental changes or emotional bursts Open
Introduction In the present letter we share the results of an analysis of more than 140,000 non traumatic arterial subarachnoid hemorrhages whereas the majority of them is expected to be after aneurysm rupture, in which we investigate a po…
Evidence for Quantum Chemical Effects in Receptor-Ligand Binding Between Integrin and Collagen Fragments — A Computational Investigation With an Impact on Tissue Repair, Neurooncolgy and Glycobiology Open
The collagen-integrin interactions are mediated by the doubly charged Mg 2+ cation. In nature this cation seems to have the optimal binding strength to stabilize this complex. It is essential that the binding is not too weak so that the co…
Efficacy of Chondroprotective Food Supplements Based on Collagen Hydrolysate and Compounds Isolated from Marine Organisms Open
Osteoarthritis belongs to the most common joint diseases in humans and animals and shows increased incidence in older patients. The bioactivities of collagen hydrolysates, sulfated glucosamine and a special fatty acid enriched dog-food wer…
Biophysical, Biochemical and Biomedical Evaluation of Collagen Hydrolysate in Comparison to Sulfated Glucosamine from Marine Organisms and Lipids of Fish Oil Origin Used as Chondroprotective Food Supplements Open
The bioactivities of collagen-hydrolysates, sulfated glucosamine and a special fatty acid enriched dog-food were tested in a dog patient study as potential therapeutic treatment options in early osteoarthritis. Biophysical, biochemical, ce…
An antarctic krill oil-based diet elicits neuroprotective effects by inhibiting oxidative stress and rebalancing the M1/M2 microglia phenotype in a cuprizone model for demyelination Open
Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system, and results in the degradation of the myelin sheath. The study investigates the neuroprotective effects of krill oil (KO) on the cuprizone (…
Asymmetry of P1 and vertebral arteries is not related to basilar tip aneurysm development or rupture Open
Objective Lately, morphological parameters of the surrounding vasculature aside from aneurysm size, specific for the aneurysm location, e.g., posterior cerebral artery angle for basilar artery tip aneurysms, could be identified to correlat…
Intracerebral aneurysm rupture due to head trauma Open
Intracranial aneurysms are known to rupture spontaneously in the absence of exogenous stimuli. Physical exercise or stress situations, with their accompanying rise in blood pressure, are often associated with aneurysm rupture. Very few cas…
Association between aneurysm hemodynamics and wall enhancement on 3D vessel wall MRI Open
OBJECTIVE Aneurysm wall enhancement (AWE) on 3D vessel wall MRI (VWMRI) has been suggested as an imaging biomarker for intracranial aneurysms (IAs) at higher risk of rupture. While computational fluid dynamics (CFD) studies have been used …
The Sialic Acid-Dependent Nematocyst Discharge Process in Relation to Its Physical-Chemical Properties Is a Role Model for Nanomedical Diagnostic and Therapeutic Tools Open
Formulas derived from theoretical physics provide important insights about the nematocyst discharge process of Cnidaria (Hydra, jellyfishes, box-jellyfishes and sea-anemones). Our model description of the fastest process in living nature r…
Endovascular treatment of intracranial ‘blister’ and dissecting aneurysms Open
Introduction Blister and dissecting aneurysms may have a different pathological background but they are commonly defined by instability of the vessel wall and bear a high risk of fatal rupture and rerupture. Lack of aneurysm sack makes tre…
New insights into the natural course and clinical relevance of Modic changes over 2 years following lumbar limited discectomy: analysis of prospective collected data Open
The pattern of Modic changes following lumbar limited discectomy is complex, not simply increasing. There is variable activity in MC Types 1 and 2 at the different time points of follow-up, and conversion from a higher grader to a lower on…
View article: Nanomedical Relevance of the Intermolecular Interaction Dynamics—Examples from Lysozymes and Insulins
Nanomedical Relevance of the Intermolecular Interaction Dynamics—Examples from Lysozymes and Insulins Open
Insulin and lysozyme share the common features of being prone to aggregate and having biomedical importance. Encapsulating lysozyme and insulin in micellar nanoparticles probably would prevent aggregation and facilitate oral drug delivery.…
Aneurysm Wall Enhancement in Black Blood Mri Correlates with Aneurysm Size. Black Blood Mri Could Serve As an Objective Criterion of Aneurysm Stability in Near Future Open
The increasing number of incidental intracranial aneurysms creates a dilemma of which aneurysms to treat and which to observe. Clinical scoring systems consider risk factors for aneurysm rupture however objective parameters for assessment …
Cavernous brain malformations and their relation to black blood MRI in respect to vessel wall contrast enhancement Open
In this limited cohort, inflammatory reactions in CCMs could not be detected by black blood MRI suggesting that the level of inflammation is minimal in these lesions and those different patho-mechanisms play a more important role in the ru…
Aneurysm Treatment Response Prediction in Follow Up Black Blood Magnetic Resonance Imaging. A Case Series Study Open
Black blood magnetic resonance imaging (MRI)is a promising imaging tool in predicting aneurysm rupture. Could it be also valuable in evaluating the treatment effect of endovascular and conservative treated aneurysms? Two patients were trea…
An extension of a multicenter, randomized, split‐face clinical trial evaluating the efficacy and safety of chromophore gel‐assisted blue light phototherapy for the treatment of acne Open
A variety of laser/light‐based devices have been reported to be effective for the treatment of acne, yet no long‐term data on efficacy and safety have been published. A first 12‐week clinical trial (“Main trial”) recently demonstrated that…
Surgical Anatomy of the Orbit in Human Cadavers–An Endoscopic Pictorial Documentation Open
Background The aim of our study was a pictorial documentation of the anatomical structures of the orbit. Methods We performed a transmaxillary endoscopic approach in nine formalin-fixed human heads. We identified and documented the anatomy…
A New Imaging Tool for Realtime Measurement of Flow Velocity in Intracranial Aneurysms Open
With modern imaging modalities of the brain a significant number of unruptured aneurysms are detected. However, not every aneurysm is prone to rupture. Because treatment morbidity is about 10% it is crucial to identify unstable aneurysms f…