Atsushi Murai
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View article: Intracellular interaction between FcRY receptor and IgY in ovarian vascular endothelial cells during avian maternal IgY transfer
Intracellular interaction between FcRY receptor and IgY in ovarian vascular endothelial cells during avian maternal IgY transfer Open
View article: Comprehensive analysis of gene expressions in ileal mucosa of chickens fed paddy rice and their IgA response to oral vaccination
Comprehensive analysis of gene expressions in ileal mucosa of chickens fed paddy rice and their IgA response to oral vaccination Open
Paddy rice ingestion increases intestinal mucin secretion and production by enhancing MUC2 gene expression and epithelial turnover. In this study, we performed a comprehensive analysis of intestinal gene expression in chickens fed paddy ri…
View article: FcRY is a key molecule controlling maternal blood IgY transfer to yolks during egg development in avian species
FcRY is a key molecule controlling maternal blood IgY transfer to yolks during egg development in avian species Open
Maternal immunoglobulin transfer plays a key role in conferring passive immunity to neonates. Maternal blood immunoglobulin Y (IgY) in avian species is transported to newly-hatched chicks in two steps: 1) IgY is transported from the matern…
View article: Potential Activity of Chicken Amniotic Fluid in Epidermal Development by Promoting Keratinocyte Differentiation
Potential Activity of Chicken Amniotic Fluid in Epidermal Development by Promoting Keratinocyte Differentiation Open
View article: C3H/HeNSlc mouse with low phospholipid transfer protein expression showed dyslipidemia
C3H/HeNSlc mouse with low phospholipid transfer protein expression showed dyslipidemia Open
High serum levels of triglycerides (TG) and low levels of high-density lipoprotein cholesterol (HDL-C) increase the risk of coronary heart disease in humans. Herein, we first reported that the C3H/HeNSlc (C3H-S) mouse, a C3H/HeN-derived su…
View article: Mimicking seasonal changes in light-dark cycle and ambient temperature modulates gut microbiome in mice under the same dietary regimen
Mimicking seasonal changes in light-dark cycle and ambient temperature modulates gut microbiome in mice under the same dietary regimen Open
To better adapt to seasonal environmental changes, physiological processes and behaviors are regulated seasonally. The gut microbiome interacts with the physiology, behavior, and even the diseases of host animals, including humans and live…
View article: Low Ascorbic Acid Intake Induces Inflammatory Changes in Intestine and Liver of ODS Rats
Low Ascorbic Acid Intake Induces Inflammatory Changes in Intestine and Liver of ODS Rats Open
We previously demonstrated that ascorbic acid (AsA) deficiency, caused by an AsA-free diet, induces inflammatory changes in the liver and intestine of osteogenic disorder Shionogi (ODS) rats that cannot synthesize AsA. However, whether low…
View article: Mimicking seasonal changes in light-dark cycle and ambient temperature modulates gut microbiome in mice under the same dietary regimen
Mimicking seasonal changes in light-dark cycle and ambient temperature modulates gut microbiome in mice under the same dietary regimen Open
To better adapt to seasonal environmental changes, physiological processes and behaviors are regulated seasonally. The gut microbiome interacts with the physiology, behavior, and even the diseases of host animals, including humans and live…
View article: Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in mice
Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in mice Open
Nonalcoholic fatty liver disease (NAFLD) is a pathological condition caused by excess triglyceride deposition in the liver. The SMXA-5 severe fatty liver mouse model has been established from the SM/J and A/J strains. To explore the geneti…
View article: Evaluation of a receptor gene responsible for maternal blood IgY transfer into egg yolks using bursectomized IgY-depleted chickens
Evaluation of a receptor gene responsible for maternal blood IgY transfer into egg yolks using bursectomized IgY-depleted chickens Open
View article: Heat Stress Causes Immune Abnormalities via Massive Damage to Effect Proliferation and Differentiation of Lymphocytes in Broiler Chickens
Heat Stress Causes Immune Abnormalities via Massive Damage to Effect Proliferation and Differentiation of Lymphocytes in Broiler Chickens Open
Broiler chickens are highly sensitive to high ambient temperatures due to their feathers, lack of skin sweat glands, and high productivity. Heat stress (HS) is a major concern for the poultry industry because it negatively affects growth a…
View article: Dietary Intake of Ascorbic Acid Attenuates Lipopolysaccharide-Induced Sepsis and Septic Inflammation in ODS Rats
Dietary Intake of Ascorbic Acid Attenuates Lipopolysaccharide-Induced Sepsis and Septic Inflammation in ODS Rats Open
The aim of this study was to verify the protective effects of ascorbic acid (AsA) against lipopolysaccharide (LPS)-induced sepsis. The study was conducted using osteogenic disorder Shionogi (ODS) rats, which are unable to synthesize AsA. M…
View article: Genetic diversity of 21 experimental chicken lines with diverse origins and genetic backgrounds
Genetic diversity of 21 experimental chicken lines with diverse origins and genetic backgrounds Open
The genetic characteristics and diversity of 21 experimental chicken lines registered with the National BioResource Project of Japan were examined using mitochondrial D-loop sequences and 54 microsatellite DNA markers. A total of 12 haplot…
View article: Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens
Characterization of Growth, Fat Deposition, and Lipid Metabolism-Related Gene Expression in Lean and Obese Meat-Type Chickens Open
Excessive fat deposition adversely affects poultry production. In this study, we investigated growth, fat deposition, and hepatic mRNA expression of 13 lipid metabolism-related genes in three unique breeds of meat-type chickens with distin…
View article: Ingestion of paddy rice increases intestinal mucin secretion and goblet cell number and prevents dextran sodium sulfate-induced intestinal barrier defect in chickens
Ingestion of paddy rice increases intestinal mucin secretion and goblet cell number and prevents dextran sodium sulfate-induced intestinal barrier defect in chickens Open
Paddy rice is a potential feed grain for chickens, whose strong gizzards can crush the hull. Here, we investigated whether paddy rice rich in hull-derived water-insoluble dietary fiber stimulates intestinal mucin secretion and production, …
View article: Fluorine-18-FDG PET/CT finding of cardiac lymphoma -a case report
Fluorine-18-FDG PET/CT finding of cardiac lymphoma -a case report Open
View article: Coffee Ingestion Suppresses Hyperglycemia in Streptozotocin-Induced Diabetic Mice
Coffee Ingestion Suppresses Hyperglycemia in Streptozotocin-Induced Diabetic Mice Open
Coffee consumption reduces the risk of type 2 diabetes in humans, but the mechanism remains unclear. In this study, we investigated the effect of coffee on pancreatic β-cells in the induction of diabetes by streptozotocin (STZ) treatment i…
View article: Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat
Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat Open
View article: Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12
Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12 Open
These results demonstrated that Fl1sa on the proximal region of chromosome 12 affected fatty liver in mice on a high-fat diet. Iah1 (isoamyl acetate-hydrolyzing esterase 1 homolog) was identified as one of the candidate genes for Fl1sa. Th…
View article: Additional file 2: of Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat
Additional file 2: of Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat Open
Expression profiles of all genes in R2 and R3 regions. (XLSX 43 kb)
View article: Additional file 5: of Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat
Additional file 5: of Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat Open
Allelle variants on chromosome 12 (Centromere-46.75Â Mb) in SM/J strain versus C57BL/6 strain. (XLSX 13 kb)
View article: Additional file 4: of Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat
Additional file 4: of Genetic dissection of the fatty liver QTL Fl1sa by using congenic mice and identification of candidate genes in the liver and epididymal fat Open
Allelle variants on chromosome 12 (Centromere-46.75Â Mb) in A/J strain versus C57BL/6 strain. (XLSX 15 kb)