Atsushi Nanashima
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View article: Salvage Esophagectomy after Photodynamic Therapy for Secondary Squamous Cell Carcinoma in a Patient with a History of Complete Response to Chemoradiotherapy for Unresectable Advanced Esophageal Neuroendocrine Carcinoma
Salvage Esophagectomy after Photodynamic Therapy for Secondary Squamous Cell Carcinoma in a Patient with a History of Complete Response to Chemoradiotherapy for Unresectable Advanced Esophageal Neuroendocrine Carcinoma Open
View article: Non-Cytotoxic Photodynamic Therapy with Talaporfin Sodium Reduces the Expression of CXCR4 and Enhances Chemotherapeutic Efficacy in Undifferentiated Gastric Cancer Cell Line HGC27
Non-Cytotoxic Photodynamic Therapy with Talaporfin Sodium Reduces the Expression of CXCR4 and Enhances Chemotherapeutic Efficacy in Undifferentiated Gastric Cancer Cell Line HGC27 Open
Gastric cancer (GC), particularly the undifferentiated type, is frequently associated with peritoneal metastasis, which significantly worsens prognosis due to its resistance to conventional treatments. Photodynamic therapy (PDT) is localiz…
View article: Recent changes in surgical outcomes and preoperative biliary drainage with the increased use of neoadjuvant chemotherapy in pancreatic cancer patients undergoing pancreatoduodenectomy: a single-center retrospective study
Recent changes in surgical outcomes and preoperative biliary drainage with the increased use of neoadjuvant chemotherapy in pancreatic cancer patients undergoing pancreatoduodenectomy: a single-center retrospective study Open
Prolonged PBD with NAC did not adversely affect surgical outcomes. MS placement provides a long patency period and is currently useful in PBD for PDAC patients undergoing PD after NAC, which requires a prolonged preoperative period. Howeve…
View article: Clinical significance of para-aortic lymph node metastasis for prognosis in patients with pancreaticobiliary cancer who underwent radical surgical resections
Clinical significance of para-aortic lymph node metastasis for prognosis in patients with pancreaticobiliary cancer who underwent radical surgical resections Open
Based on these findings, radical resection may be considered for PC patients with isolated PALN metastases only in the absence of additional adverse prognostic factors. Prospective clinical trials are warranted to further refine the criter…
View article: Managing uncontrolled bleeding in elective surgery: The role of damage control techniques
Managing uncontrolled bleeding in elective surgery: The role of damage control techniques Open
View article: Relationship between survival outcomes in patients with colorectal liver metastasis undergoing hepatectomy and significance of fibrotic markers for liver injury assessment
Relationship between survival outcomes in patients with colorectal liver metastasis undergoing hepatectomy and significance of fibrotic markers for liver injury assessment Open
Fibrotic markers indicating chemotherapy or repeated surgical liver injury were not significant predictive factors reflecting cancer malignant behaviors or patient overall survival, contrary to our hypothesis. The current overall survival …
View article: Clinical significances of liver fibrotic markers in patients with cholangiocarcinoma after radical resections
Clinical significances of liver fibrotic markers in patients with cholangiocarcinoma after radical resections Open
Objective: We examined the relation between several fibrotic markers reflecting liver parenchymal injury and conventional liver function or surgical outcomes in 67 patients with cholangiocarcinoma who underwent biliary drainage for obstruc…
View article: Submucosal hemorrhage of the esophagus: a case report
Submucosal hemorrhage of the esophagus: a case report Open
View article: Liver-expressed antimicrobial peptide 2 is a hepatokine regulated by ghrelin, nutrients, and body weight
Liver-expressed antimicrobial peptide 2 is a hepatokine regulated by ghrelin, nutrients, and body weight Open
View article: Does bile exposure during surgery affect the postoperative recovery and complications of pediatric patients with choledochal cysts treated by laparoscopic surgery?
Does bile exposure during surgery affect the postoperative recovery and complications of pediatric patients with choledochal cysts treated by laparoscopic surgery? Open
Purpose We aimed to investigate the impact of intraoperative bile exposure (BE) on postoperative recovery and complications in pediatric patients with choledochal cysts (CCs). Methods We reviewed the medical records of CC patients who unde…
View article: Acceptance of Virtual Reality Simulation Training for Stoma Care by Healthcare Providers: A Pilot Questionnaire Study After Viewing Prototype Imagings
Acceptance of Virtual Reality Simulation Training for Stoma Care by Healthcare Providers: A Pilot Questionnaire Study After Viewing Prototype Imagings Open
View article: A Case of Primary Malignant Melanoma of the Small Intestine with Preoperative Pathology Diagnosed by Transanal Small Bowel Balloon Endoscopy
A Case of Primary Malignant Melanoma of the Small Intestine with Preoperative Pathology Diagnosed by Transanal Small Bowel Balloon Endoscopy Open
View article: A Case of Transhiatal Esophagectomy for Thoracic Esophageal Cancer Diagnosed During Follow-Up after Total Laryngopharyngoesophagectomy
A Case of Transhiatal Esophagectomy for Thoracic Esophageal Cancer Diagnosed During Follow-Up after Total Laryngopharyngoesophagectomy Open
View article: Questionnaire survey of virtual reality experiences of digestive surgery at a rural academic institute: A pilot study for pre-surgical education
Questionnaire survey of virtual reality experiences of digestive surgery at a rural academic institute: A pilot study for pre-surgical education Open
We developed a prototype VR platform, VECTORS L&M (VLM), aiming to enhance the understanding of digestive surgery for students, interns, and young surgeons by limiting costs. Its efficacy was assessed via questionnaires before implementati…
View article: Successful treatment of esophageal perforation due to black esophagus (acute esophageal necrosis): a case report
Successful treatment of esophageal perforation due to black esophagus (acute esophageal necrosis): a case report Open
View article: Lifetime Follow-Up of a Patient with Metastatic Prostate Cancer Undergoing Multiple Surgical Resections: A Case Report
Lifetime Follow-Up of a Patient with Metastatic Prostate Cancer Undergoing Multiple Surgical Resections: A Case Report Open
BACKGROUND Prostate cancer (PC) often metastasizes after primary resection, and long-term survival following surgical removal of multiple pulmonary metastases is rare. We present a case of a surgeon who demonstrated long-term survival afte…
View article: Successful Right Hepatectomy for Recurrent Liver Tumor Originating from an Inferior Vena Cava Leiomyosarcoma: A Follow-Up Case Report
Successful Right Hepatectomy for Recurrent Liver Tumor Originating from an Inferior Vena Cava Leiomyosarcoma: A Follow-Up Case Report Open
BACKGROUND Leiomyosarcoma (LMS) of the inferior vena cava (IVC) is a rare malignancy, and complete resection may provide better patient survival. Hepatectomy for intrahepatic tumor recurrence has not been previously reported. CASE REPORT A…
View article: Circulating maternal chimeric cells have an impact on the outcome of biliary atresia
Circulating maternal chimeric cells have an impact on the outcome of biliary atresia Open
Introduction We aimed to quantify the DNA of maternal chimeric (MC) cells in the peripheral blood of the BA patients and investigated the impact on the outcome. Methods Patients with progressive jaundice because of no bile flow, which nece…
View article: Sonazoid-enhanced intraoperative ultrasonography in patients with biliopancreatic diseases: A preliminary study
Sonazoid-enhanced intraoperative ultrasonography in patients with biliopancreatic diseases: A preliminary study Open
Background Ultrasonography using Sonazoid, a novel contrast agent containing microbubbles is a useful diagnostic modality for intrahepatic mass lesions by specific characteristics in two phases of contrast enhancement of early vascular per…
View article: Curative remnant total pancreatectomy for recurrent pancreatic acinar cell carcinoma: A case report
Curative remnant total pancreatectomy for recurrent pancreatic acinar cell carcinoma: A case report Open
View article: Knowledge survey regarding blast wound education of student doctors at a local academic medical university in Japan
Knowledge survey regarding blast wound education of student doctors at a local academic medical university in Japan Open
Objective: To improve knowledge about blast injury for medical student doctors or surgeons. In the modern uncertain era, education and training programs for blast injuries for medical student doctors or surgeons are recently necessary worl…
View article: An adult case of a retroperitoneal isolated enteric duplication cyst with the imaging changes over time
An adult case of a retroperitoneal isolated enteric duplication cyst with the imaging changes over time Open
Background Adult cases of retroperitoneal isolated enteric duplication cyst (IEDC) are rare, with only 17 case reports in the relevant literature. We herein present a case, which was characterized by changes in intra-cystic density on comp…
View article: A 3D Quantitative MRC Modeling Images Detected Case of Intrahepatic Biliary Stricture Diseases
A 3D Quantitative MRC Modeling Images Detected Case of Intrahepatic Biliary Stricture Diseases Open
In the future, the application of quantitative imaging and computational analysis will reduce the burden on radiologists. We herein report 8 pilot cases both with and without intrahepatic biliary stricture (IHBS) diseases which have been a…
View article: Malignant pheochromocytoma with liver invasion treated successfully by combined retroperitoneal laparoscopic control of arterial in-flow followed by open hepatectomy: A case report
Malignant pheochromocytoma with liver invasion treated successfully by combined retroperitoneal laparoscopic control of arterial in-flow followed by open hepatectomy: A case report Open
View article: A Case of Rectal Carcinoma with Synchronous Neuroendocrine Differentiated Prostate Carcinoma That Spread to the Mesorectal Lymph Node
A Case of Rectal Carcinoma with Synchronous Neuroendocrine Differentiated Prostate Carcinoma That Spread to the Mesorectal Lymph Node Open
症例は75歳の男性で，排尿障害，前立腺特異抗原（prostate specific antigen；以下，PSAと略記）高値にて針生検を施行したところ前立腺癌と診断され，精査中に下部直腸（Rb）前壁に1/3周性Type 2病変を認めた．骨盤MRIで前立腺癌は肛門管直上で直腸壁に接しており，直腸癌とも近接していた．直腸間膜リンパ節（mesorectal lymph node；以下，MLNと略記），側方および鼠径部に多数のリンパ節腫大，および複数の骨転移を認めた．前立腺癌（St…
View article: Does Risk Calculator by Nationwide Survey Match The Postoperative Outcome in Patients Who Underwent Major Hepatectomy?
Does Risk Calculator by Nationwide Survey Match The Postoperative Outcome in Patients Who Underwent Major Hepatectomy? Open
Background: To clarify significance of the present National Clinical Database risk calculator (NCD-RC) for hepatectomy in Japan, relationship between perioperative parameters or outcomes in major hepatectomy and the mortality rate by NCD-R…
View article: Nasogastric administration of lenvatinib solution in a mechanically ventilated patient with rapidly growing anaplastic thyroid cancer
Nasogastric administration of lenvatinib solution in a mechanically ventilated patient with rapidly growing anaplastic thyroid cancer Open
Summary A 54-year-old woman was referred to our hospital with a cervical tumor. CT revealed a cervical tumor extending to the upper mediastinum, tracheal deviation and tumor infiltration in the cervical vessels. She was followed-up because…
View article: Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells
Photodynamic Therapy Using a Novel Phosphorus Tetraphenylporphyrin Induces an Anticancer Effect via Bax/Bcl-xL-related Mitochondrial Apoptosis in Biliary Cancer Cells Open
Photodynamic therapy (PDT) uses photosensitizer activation by light of a specific wavelength, and is a promising treatment for various cancers; however, the detailed mechanism of PDT remains unclear. Therefore, we investigated the anticanc…
View article: AirSeal was Useful in Laparoscopic Surgery for Perforated Appendicitis During Pregnancy
AirSeal was Useful in Laparoscopic Surgery for Perforated Appendicitis During Pregnancy Open
Introduction: Acute appendicitis is the most common general surgical problem during pregnancy.Laparoscopic appendectomy has been gaining widespread popularity and has been accepted as a minimally invasive surgery based on evidence for its …
View article: Neutrophil-to-Lymphocyte Ratio and Intratumoral CD45RO-Positive T Cells as Predictive Factors for Longer Survival of Patients with Colorectal Liver Metastasis after Hepatectomy
Neutrophil-to-Lymphocyte Ratio and Intratumoral CD45RO-Positive T Cells as Predictive Factors for Longer Survival of Patients with Colorectal Liver Metastasis after Hepatectomy Open
Colorectal cancer is the fourth most common malignancy across the world, and over 50% of patients had colorectal liver metastases (CLM). Activated neutrophils and tumor-infiltrating lymphocytes (TILs) are considered to interrupt progressio…