Audrey K. Cook
YOU?
Author Swipe
View article: There is no significant difference in the treatment of aspiration pneumonia in dogs with ampicillin-sulbactam versus ampicillin-sulbactam and enrofloxacin
There is no significant difference in the treatment of aspiration pneumonia in dogs with ampicillin-sulbactam versus ampicillin-sulbactam and enrofloxacin Open
Objective Describe outcomes for dogs with aspiration pneumonia (AP) initially treated with ampicillin-sulbactam (AS) alone (monotherapy [MT]), initially with AS and enrofloxacin (initial dual therapy [iDT]), or initially with AS and later …
View article: Fluoroscopic-assisted transesophageal retrograde nasopharyngoscopy in dogs and cats
Fluoroscopic-assisted transesophageal retrograde nasopharyngoscopy in dogs and cats Open
Objective To devise a safe and effective method for accessing the nasopharynx (NP) in dogs and cats with complex or challenging disorders such as choanal tumors or entrapped foreign material. Animals Dogs and cats. Methods The patient is p…
View article: Assessment of Exenatide Extended‐Release for Maintenance of Diabetic Remission in Cats
Assessment of Exenatide Extended‐Release for Maintenance of Diabetic Remission in Cats Open
Background Insulin‐treated diabetic cats frequently achieve transient remission. The glucagon‐like peptide‐1 receptor agonist, exenatide extended‐release (exenatide‐ER), preserves β cell function in people with type 2 diabetes mellitus (DM…
View article: Thoracic radiographic findings in cats with feline infectious peritonitis
Thoracic radiographic findings in cats with feline infectious peritonitis Open
Objectives The objective of this study was to describe thoracic radiographic findings and associated histopathological changes (where available) in cats with feline infectious peritonitis (FIP). Methods This was a retrospective descriptive…
View article: Walkability Analysis of the Self-Guided Walking Tour in Downtown Durham, North Carolina
Walkability Analysis of the Self-Guided Walking Tour in Downtown Durham, North Carolina Open
This study examines the walkability of the self-guided walking tour in the City Center district of Downtown Durham, assessing its usability and pedestrian appeal. Utilizing a modified Level of Service (LOS) analysis and qualitative mapping…
View article: Velagliflozin, a once-daily, liquid, oral SGLT2 inhibitor, is effective as a stand-alone therapy for feline diabetes mellitus: the SENSATION study
Velagliflozin, a once-daily, liquid, oral SGLT2 inhibitor, is effective as a stand-alone therapy for feline diabetes mellitus: the SENSATION study Open
OBJECTIVE To investigate safety and effectiveness of velagliflozin oral solution as sole therapy in naïve and previously insulin-treated diabetic cats. ANIMALS 252 client-owned cats receiving ≥ 2 doses of velagliflozin; 214 (85%) naïve dia…
View article: <scp>SGLT2</scp> inhibitor use in the management of feline diabetes mellitus
<span>SGLT2</span> inhibitor use in the management of feline diabetes mellitus Open
Sodium‐glucose cotransporter‐2 (SGLT2) inhibitors are routinely used in the management of human type 2 diabetes and have been shown to effectively mitigate hyperglycemia and reduce the risks of cardiovascular and renal compromise. Two SGLT…
View article: Issue Information
Issue Information Open
Prevalence of gastroesophageal reflux in dogs undergoing MRI for a thoracolumbar vertebral column pathologyEpidemiology and risk factors for mammary tumours in female cats Comparison of axillary and inguinal temperature with rectal tempera…
View article: Clinical utility of fungal culture and antifungal susceptibility in cats and dogs with histoplasmosis
Clinical utility of fungal culture and antifungal susceptibility in cats and dogs with histoplasmosis Open
Background Culture can be used for diagnosis and antifungal susceptibility testing in animals with fungal infections. Limited information is available regarding the diagnostic performance of culture and the susceptibility patterns of Histo…
View article: Clinical features of muscle stiffness in 37 dogs with concurrent naturally occurring hypercortisolism
Clinical features of muscle stiffness in 37 dogs with concurrent naturally occurring hypercortisolism Open
Background Severe muscle stiffness (SMS) in dogs with hypercortisolism (HC) is uncommon. Objectives To evaluate signalment, presentation, treatments, and long‐term outcomes of dogs with concurrent HC and SMS. Animals Thirty‐seven dogs. Met…
View article: Effect of withholding food versus feeding on creatinine, symmetric dimethylarginine, cholesterol, triglycerides, and other biochemical analytes in 100 healthy dogs
Effect of withholding food versus feeding on creatinine, symmetric dimethylarginine, cholesterol, triglycerides, and other biochemical analytes in 100 healthy dogs Open
Background Withholding food is often recommended before collection of blood for routine biochemical analysis in dogs despite a paucity of evidence to support this requirement. Objectives To compare measurements of selected biochemical anal…
View article: Issue Information
Issue Information Open
Front cover: Transmission electron microscopy images of uEVs (white arrow) isolated via ultrafiltration + SEC at ×11,500 magnification.Particles with a "cup-shaped" morphology and within the expected size range were present in all preparat…
View article: Prospective evaluation of complications associated with transesophageal echocardiography in dogs with congenital heart disease
Prospective evaluation of complications associated with transesophageal echocardiography in dogs with congenital heart disease Open
Background Transesophageal echocardiography (TEE) is useful in the assessment and procedural monitoring of congenital heart disease (CHD) with a relatively low complication rate in humans. Objectives To evaluate the safety of TEE and repor…
View article: Replacing a Veterinary Physiology Endocrinology Lecture with a Blended Learning Approach Using an Everyday Analogy
Replacing a Veterinary Physiology Endocrinology Lecture with a Blended Learning Approach Using an Everyday Analogy Open
Understanding scientific concepts and processes is critical for veterinary education. This article outlines the impact of blended learning and the use of an analogy on student understanding of the hypothalamic-pituitary-target gland axis o…
View article: <scp><i>Heterobilharzia americana</i></scp>infection in dogs: A retrospective study of 60 cases (2010‐2019)
<span><i>Heterobilharzia americana</i></span>infection in dogs: A retrospective study of 60 cases (2010‐2019) Open
Background The trematode Heterobilharzia americana ( HA ) causes granulomatous gastrointestinal and hepatic disease in dogs. Before 2008, diagnosis relied on saline fecal sedimentation or histopathology, and earlier reports primarily descr…
View article: Feline comorbidities: Recognition, diagnosis and management of the cushingoid diabetic
Feline comorbidities: Recognition, diagnosis and management of the cushingoid diabetic Open
Practical relevance: Diabetes mellitus (DM) is a common feline endocrinopathy, and is often driven by underlying insulin resistance with associated pancreatic beta (β)-cell dysfunction. Although spontaneous hyperadrenocorticism (HAC) with …
View article: Impact of preheparinization and sample volume on routine hematology findings in healthy cats
Impact of preheparinization and sample volume on routine hematology findings in healthy cats Open
Objectives It can be challenging to collect sufficient blood from feline patients for both a biochemical profile and a complete blood count (CBC). The ability to generate accurate hematologic and biochemical data from a single, small (<2 m…
View article: Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway
Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway Open
Epidemiological studies link long term exposure to xenoestrogen Bisphenol-A to adverse cardiovascular effects. Our previous results show that BPA induces hypertension by a mechanism involving CamKII activation and increased redox stress ca…
View article: Bacterial Biogeography of the Colon in Dogs With Chronic Inflammatory Enteropathy
Bacterial Biogeography of the Colon in Dogs With Chronic Inflammatory Enteropathy Open
The intestinal microbiota is believed to play a role in the pathogenesis of inflammatory bowel disease in humans and chronic inflammatory enteropathy (CIE) in dogs. While most previous studies have described the gut microbiota using sequen…
View article: Untargeted metabolomic profiling of serum from dogs with chronic hepatic disease
Untargeted metabolomic profiling of serum from dogs with chronic hepatic disease Open
Background Chronic hepatopathies present a diagnostic challenge, with different diseases being associated with similar clinical and laboratory findings. Characterization of dogs with chronic hepatopathies can be difficult and require costl…
View article: Piecemeal endoscopic polypoidectomy for the management of a canine pharyngeal hemangiosarcoma.
Piecemeal endoscopic polypoidectomy for the management of a canine pharyngeal hemangiosarcoma. Open
A 7-year-old castrated male Maltese dog was presented for increased respiratory sounds, inability to bark, dysphagia, and hyporexia. Radiographs revealed an ovoid, opaque mass in the caudal nasopharynx. An airway examination and computed t…
View article: Comparison of intestinal expression of the apical sodium‐dependent bile acid transporter between dogs with and without chronic inflammatory enteropathy
Comparison of intestinal expression of the apical sodium‐dependent bile acid transporter between dogs with and without chronic inflammatory enteropathy Open
Background Intestinal absorption of bile acids is mediated by the apical sodium‐dependent bile acid transporter (ASBT). Fecal bile acid dysmetabolism has been reported in dogs with chronic inflammatory enteropathy (CIE). Objective Characte…
View article: Pretreatment <i>Histoplasma capsulatum</i> urine enzymatic immunoassay concentrations do not correlate with outcome but may be influenced by renal function in cats with histoplasmosis
Pretreatment <i>Histoplasma capsulatum</i> urine enzymatic immunoassay concentrations do not correlate with outcome but may be influenced by renal function in cats with histoplasmosis Open
Objectives The objective of this study was to determine if urine Histoplasma antigen (HAg) enzyme immunoassay (EIA) concentrations at the time of diagnosis and prior to the administration of antifungal agents are predictive of outcome for …
View article: Opportunistic Invasive Cutaneous Fungal Infections Associated with Administration of Cyclosporine to Dogs with Immune‐mediated Disease
Opportunistic Invasive Cutaneous Fungal Infections Associated with Administration of Cyclosporine to Dogs with Immune‐mediated Disease Open
Background Opportunistic invasive fungal infections ( OIFI s) occur in dogs administered immunosuppressive medications. However, the epidemiology of OIFI s among dogs undergoing immunosuppressive treatment is poorly understood. The aims of…
View article: Blood Transfusions in Dogs and Cats Receiving Hemodialysis: 230 Cases (June 1997–September 2012)
Blood Transfusions in Dogs and Cats Receiving Hemodialysis: 230 Cases (June 1997–September 2012) Open
Background Multiple factors exist that contribute to anemia in dogs and cats receiving hemodialysis, can necessitate transfusion. Objectives To describe blood product usage in dogs and cats with acute and chronic kidney disease that were t…
View article: Subclinical bacteriuria in cats: prevalence, findings on contemporaneous urinalyses and clinical risk factors
Subclinical bacteriuria in cats: prevalence, findings on contemporaneous urinalyses and clinical risk factors Open
Objectives Subclinical bacteriuria (SB) is bacterial colonization of the urinary tract in the absence of clinical signs. The purposes of this study were to determine the prevalence of SB in cats and to describe results of the contemporaneo…
View article: Pancreatic Lipase Immunoreactivity in Serum of Dogs with Diabetic Ketoacidosis
Pancreatic Lipase Immunoreactivity in Serum of Dogs with Diabetic Ketoacidosis Open
Background Diabetic ketoacidosis ( DKA ) is a relatively common endocrine disorder in dogs and is routinely associated with concurrent pancreatic injury. Objectives The aims of this study were to determine the prevalence of pancreatic inju…