Audrius Dulskas
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View article: A novel laparoscopic magnet-assisted technique for extracting a retained needle after repair of PEG-related gastrocolic perforation in a neurologically impaired adolescent: a case report
A novel laparoscopic magnet-assisted technique for extracting a retained needle after repair of PEG-related gastrocolic perforation in a neurologically impaired adolescent: a case report Open
Background Percutaneous endoscopic gastrostomy (PEG) is widely used to provide long-term enteral nutrition in neurologically impaired children. Although generally safe, PEG placement may rarely result in major complications such as viscera…
View article: Quality of Life after Treatment of Presacral Tumors
Quality of Life after Treatment of Presacral Tumors Open
Background. Presacral tumors are rare and anatomically complex lesions located between the rectum and the sacrum. Due to their often asymptomatic nature, most cases are diagnosed incidentally. Although typically benign, these tumors are su…
View article: Colorectal and emergency surgical patients in the literature supporting EHS and AHS guidelines on abdominal wound closure: a granular analysis
Colorectal and emergency surgical patients in the literature supporting EHS and AHS guidelines on abdominal wound closure: a granular analysis Open
View article: Correction: Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study
Correction: Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study Open
View article: Lymph node mapping-based optimal bowel-resection margin and central radicality in colon cancer surgery: an international, prospective, observational cohort study
Lymph node mapping-based optimal bowel-resection margin and central radicality in colon cancer surgery: an international, prospective, observational cohort study Open
Background: Substantial variations in the extent of lymphadenectomy are acknowledged internationally in colon cancer surgery because essential data for standardization, including the anatomical distribution of metastatic lymph nodes (LN), …
View article: Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study
Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study Open
View article: Quality of life following ileostomy takedown: single-centre, retrospective clinical trial—does closure time matter?
Quality of life following ileostomy takedown: single-centre, retrospective clinical trial—does closure time matter? Open
This study was a secondary analysis of the prospective trial registered at ClinicalTrials.gov no. NCT03607370, 01.07.2017.
View article: Oral Microbiota: an Innovative Approach to Colorectal Cancer Diagnosis
Oral Microbiota: an Innovative Approach to Colorectal Cancer Diagnosis Open
Background. Colorectal cancer is one of the most common and deadly oncological diseases worldwide. Current early diagnostic methods, such as the fecal occult blood test, often lack sufficient sensitivity and specificity, making them potent…
View article: PARP9-PARP13-PARP14 axis tunes colorectal cancer response to radiotherapy
PARP9-PARP13-PARP14 axis tunes colorectal cancer response to radiotherapy Open
Background Colorectal cancer (CRC) is the third most prevalent cancer worldwide. Despite substantial advancements in CRC therapy in recent years, ionizing radiation (IR) continues to be the predominant treatment for colon malignances. Howe…
View article: Differences in cause-specific mortality between healthcare workers and all other employees in Lithuania, 2011–2019
Differences in cause-specific mortality between healthcare workers and all other employees in Lithuania, 2011–2019 Open
Background Healthcare workers face health risks, including stress, burnout, and communicable diseases, leading to higher mortality rates. However, excess mortality diminishes with better disease control and lifestyle factors. Methods The s…
View article: A review on the role of microRNA-340 and curcumin in apoptosis and metastasis in colorectal cancer
A review on the role of microRNA-340 and curcumin in apoptosis and metastasis in colorectal cancer Open
MicroRNAs (miRNAs), which are small non-coding RNA molecules, play a crucial role in regulating gene expression following transcription. They are essential for cellular functions like proliferation, metastasis, apoptosis, and differentiati…
View article: Early urinary catheter removal in patients undergoing rectal cancer surgery: a randomized controlled trial on silodosin versus no pharmacological treatment on urinary function in the early postoperative period
Early urinary catheter removal in patients undergoing rectal cancer surgery: a randomized controlled trial on silodosin versus no pharmacological treatment on urinary function in the early postoperative period Open
Early urinary catheter removal on the first postoperative day was safe in both groups. The use of the oral α-antagonist silodosin did not provide additional benefits in preventing lower urinary tract symptoms in patients undergoing rectal …
View article: The Role of microRNA-31 in the Initiation and rogression of Colorectal Cancer
The Role of microRNA-31 in the Initiation and rogression of Colorectal Cancer Open
miR-31 is critically involved in the initiation and progression of CRC by regulating multiple pathways essential for tumorigenesis and influencing various cellular func- tions, such as proliferation, apoptosis, epithelial-mesenchymal trans…
View article: Young Onset Colorectal Cancer
Young Onset Colorectal Cancer Open
Early onset colorectal cancer - colorectal cacner, appearing in a patient population below 50 years of age. Disease is more aggressive, and diagnosis is more likely in an advanced stage. The increase in the incidence of this form of diseas…
View article: Interim analysis of single – centre randomised controlled trial on incisional hernia repair with vs without synthetic mesh fixation
Interim analysis of single – centre randomised controlled trial on incisional hernia repair with vs without synthetic mesh fixation Open
View article: Exploring the Role of MiR-373 in Colorectal Cancer Development and Progression
Exploring the Role of MiR-373 in Colorectal Cancer Development and Progression Open
Context: Colorectal cancer (CRC) is a leading cause of cancer-related deaths globally. Its progression is influenced by various molecular factors, including the dysregulation of microRNAs (miRNAs). MiR-373 is an oncogenic miRNA implicated …
View article: Skrandžio vėžio patikros programa: literatūros apžvalga
Skrandžio vėžio patikros programa: literatūros apžvalga Open
Objective. To analyze the causes and consequences of global gastric cancer prevalence and justify the need for a preventive program in Lithuania. Methods. Data for the study was gathered from the PubMed database, articles and scientific pa…
View article: Editorial: Low anterior resection syndrome—treatment possibilities
Editorial: Low anterior resection syndrome—treatment possibilities Open
View article: Systematic review of the needs and health-related quality of life domains relevant to people surviving cancer in Europe
Systematic review of the needs and health-related quality of life domains relevant to people surviving cancer in Europe Open
View article: Recent Progress in Nanoparticle-Driven Drug Delivery Strategies for Cancer Therapy: Focus on Colorectal Cancer
Recent Progress in Nanoparticle-Driven Drug Delivery Strategies for Cancer Therapy: Focus on Colorectal Cancer Open
Context: Nanotechnology, specifically nanoparticles, has revolutionized cancer therapy through enhanced drug delivery, precise imaging, and accurate diagnosis. Their ability to target cancer cells directly with minimal side effects makes t…
View article: Global multi-societies endorsement of the MAFLD definition
Global multi-societies endorsement of the MAFLD definition Open
View article: Anastomotic leak after manual circular stapled left-sided bowel surgery: analysis of technology-, disease-, and patient-related factors
Anastomotic leak after manual circular stapled left-sided bowel surgery: analysis of technology-, disease-, and patient-related factors Open
Background Anastomotic leak rates after colorectal surgery remain high. In most left-sided colon and rectal resection surgeries, a circular stapler is utilized to create the primary bowel anastomosis. However, it remains unclear whether a …
View article: First clinical experience using augmented intelligence in robotic colorectal surgery with the Senhance robotic platform
First clinical experience using augmented intelligence in robotic colorectal surgery with the Senhance robotic platform Open
View article: Impact of mechanical bowel preparation on the gut microbiome of patients undergoing left-sided colorectal cancer surgery: randomized clinical trial
Impact of mechanical bowel preparation on the gut microbiome of patients undergoing left-sided colorectal cancer surgery: randomized clinical trial Open
Background Postoperative complications after colorectal cancer surgery have been linked to the gut microbiome. However, the impact of mechanical bowel preparation using oral preparation agents or rectal enema on postoperative infections re…
View article: Liquid biopsy for monitoring minimal residual disease in colorectal cancer: A promising approach with clinical implications
Liquid biopsy for monitoring minimal residual disease in colorectal cancer: A promising approach with clinical implications Open
Colorectal cancer (CRC) is a global health concern, ranking among the leading causes of cancer-related mortality. This review critically evaluates the role of liquid biopsy in detecting minimal residual disease (MRD) in CRC. The increasing…
View article: Anal fissure treatment in 2022 - A global snapshot audit conducted by the International Society of University Colon and Rectal Surgeons (ISUCRS)
Anal fissure treatment in 2022 - A global snapshot audit conducted by the International Society of University Colon and Rectal Surgeons (ISUCRS) Open
Background An anal fissure is a longitudinal tear in the mucosa of the anal canal, distal to the dentate line. It is usually situated in the posterior midline but can occur in any quadrant. This condition affects both genders and is associ…
View article: Additional Cover
Additional Cover Open
The cover image is based on the Short Communication Epigenetic age oscillates during the day by Karolis Koncevičius et al., https://doi.org/10.1111/acel.14170 [Image: see text]
View article: Prostate Adenocarcinoma with Signet-Ring Cells and Features of Mucin: A Clinical Case and Literature Review
Prostate Adenocarcinoma with Signet-Ring Cells and Features of Mucin: A Clinical Case and Literature Review Open
Introduction: Signet-ring cells are typically associated with mucin-secreting epithelium; thus, they are most commonly found in the gastrointestinal tract, but not exclusively. Primary signet-ring cell carcinoma of the prostate is a rare a…
View article: Immune Checkpoint Blockade in Melanoma – Earlier is Better?
Immune Checkpoint Blockade in Melanoma – Earlier is Better? Open
Administering checkpoint inhibition before surgery, known as neoadjuvant therapy, shows promise in treating bulky yet resectable melanomas, and researchers are investigating its potential in various other cancer types. This approach boasts…
View article: Acute Appendicitis within Incarcerated Hernia Sac: A Case Report and Literature Review
Acute Appendicitis within Incarcerated Hernia Sac: A Case Report and Literature Review Open
Background: Localization of acute appendicitis in a hernia sac is a rare phenomenon with a frequency of around 0.08 - 1 %. Even fewer cases of postoperative hernias with a vermiform appendix in the hernia sac have been described. We select…