Explanipedia

Virtual screening, molecular docking, and molecular dynamics simulation reveal new insights into RNA polymerase inhibition for anti-tuberculosis drug discovery. Open

Taufik Muhammad Fakih, Farendina Suarantika, Aulia Fikri Hidayat, Dwi Syah Fitra Ramadhan, Muchtaridi Muchtaridi · 2025

This study highlights the effectiveness of combining virtual screening, molecular docking, MD simulations, and MM-PBSA analysis in identifying promising RNAP inhibitors. The results establish a strong foundation for further experimental va…

Pengabdian Masyarakat melalui Edukasi Pencegahan Perundungan di SDN Pamoyanan Desa Padamaju Open

Eva Manfaaatin, Alfa Rohmatin, Rista Erika, Tedi Gandara, Aulia Fikri Hidayat , et al. · 2025

Bullying remains a serious problem in primary education because it affects children’s psychosocial development, academic performance, and mental health. This community service program focused on educational efforts to prevent bullying at S…

The Impact of Performance Factors on Performance on Quality in Project Implementation Open

Hermawan Tedi, Oktavia Futri Fajarni, Aminudin Aminudin, Marpaung Richo Ronald, Iman Darul , et al. · 2025

This study aims to analyze the impact of various performance factors on contractor performance in the implementation project, as part of the National Police's institutional transformation toward a predictive, responsive, and transparent wo…

A Review on QbD-Driven Optimization of Lipid Nanoparticles for Oral Drug Delivery: From Framework to Formulation Open

Aulia Fikri Hidayat, Yoga Windhu Wardhana, Suwendar Suwendar, Ahmed Fouad Abdelwahab Mohammed, Safwat A. Mahmoud , et al. · 2025

Oral administration is the most preferred route for drug delivery due to its convenience, non-invasiveness, and patient compliance. However, it is challenged by gastrointestinal barriers, enzymatic degradation, and first-pass metabolism, w…

Improving the solubility of remdesivir–cyclodextrin encapsulations in water-saturated 1-octanol solution: A molecular dynamics simulation study Open

Sani Ega Priani, Aulia Fikri Hidayat, Taufik Muhammad Fakih · 2025

Remdesivir was selected as a treatment for viral infections due to its efficacy as an antiviral agent against various RNA viruses such as Ebola and coronaviruses. The drug exerts its benefits during the later stages of viral infection, par…

PERANCANGAN IDENTITAS VISUAL PRODUK TEH HERBAL BUNGA TELANG UNTUK MENINGKATKAN DAYA TARIK KONSUMEN DI DESA CIKELAT Open

Irsa Novia, Aulia Fikri Hidayat, Rizqi Ahmad Gozali, Zaenal Alamsyah · 2025

Telang Flower Herbal Tea is a herbal drink produced from butterfly pea flowers (Clitoria ternatea), a plant that grows abundantly in tropical areas, including Indonesia. Butterfly pea flower, also known as butterfly pea flower or blue flow…

Molecular simulation-based evaluation of anti-inflammatory properties of natural compounds derived from tobacco (Nicotiana tabacum L.): Computational multi-target approaches Open

Vinda Maharani Patricia, Aulia Fikri Hidayat, Taufik Muhammad Fakih · 2024

Various components of the tobacco plant ( Nicotiana tabacum L.) have undergone pharmacological assessment to highlight their traditional role in addressing different health conditions. The anti-inflammatory properties of thirteen natural s…

Dendrimer sebagai Sistem Penghantaran Obat Terapi Kanker Payudara Open

Azmi Aziz, Aulia Fikri Hidayat, Ratih Aryani · 2024

Breast cancer is one of the most common types of cancer in women and a leading cause of cancer-related deaths over the past two decades. Current breast cancer therapies using anticancer drugs face challenges such as non-specific toxicity, …

Formulasi Sediaan Nanoemulsi Minyak Biji Rosehip Open

Ratnasari, Aulia Fikri Hidayat, Hanifa Rahma · 2024

The skin is the outermost organ of the body which plays a role in the process of protecting against UV radiation which can trigger ROS (Reactive Oxygen Species). Rosehip seed oil (Rosa canina L.) has activity as an antioxidant which can be…

Formulasi dan Uji Aktivitas Antioksidan Sediaan Emulgel Ekstrak Daun Tanjung (Mimusops elengi L.) Open

Nashita Rafawziya, Aulia Fikri Hidayat, Sani Ega Priani · 2024

Antioxidants are compounds that function to prevent, inhibit, or reduce free radical and oxidant reactions, and prevent tissue damage. One of the plants as an antioxidant to counteract free radicals is the cape leaf. Antioxidant activity t…

Formulasi dan Karakterisasi Nanogel Ekstrak Etanol Daun Katuk (Breynia androgyna L.) Open

Fika Nur Hasyaeni, Aulia Fikri Hidayat, Ratih Aryani · 2024

Katuk leaf is a medicinal plant in Southeast Asia, including Indonesia. Nanogels are gels with small particle sizes and large surface areas that can increase the penetration of active compounds. Objective: Formulation and characterization …

Pengembangan Emulsi Pickering Minyak Atsiri sebagai Antibakteri Open

Rafika Susun Nursunda, Aulia Fikri Hidayat, Sani Ega Priani · 2024

Bacteria are organisms that can enter the digestive tract which can cause several diseases, so it is necessary to be given an antibacterial. Essential is the result of the secondary metabolism of plants containing volatile compounds known …

Karakterisasi Minyak Nilam serta Evaluasi Sediaan Nanoemulsi Minyak Nilam (Pogostemon cablin Benth) Open

Natasya Delarespita, Aulia Fikri Hidayat, Hanifa Rahma · 2024

Patchouli is one of the natural ingredients that can be utilized in the health sector, one of which is as an antimicrobial. Essential oil contained in patchouli plants (Pogostemon cablin Benth) is known to have antimicrobial activity in th…

Metode Kokristal, Koamorf, Kompleks Inklusi, dan Dispersi Padat dalam Upaya Modifikasi Sifat Fisikokimia Zat Aktif Farmasi Open

Nadya Azzahra, Fitrianti Darusman, Aulia Fikri Hidayat · 2024

Modification of the physicochemical properties of active pharmaceutical ingredients is an important step in enhancing the solubility and bioavailability of drugs. Several modifications that can be implemented include cocrystals, coamorphou…

In Silico Coformer Screening for Mefenamic Acid Cocrystallization Open

Aulia Fikri Hidayat, Taufik Muhammad Fakih, Gita Cahya Eka Darma, Ratu Choesrina · 2024

Cocrystallization is a widely used approach to enhance the solubility and dissolution characteristics of poorly soluble drugs. A pharmaceutical cocrystal is a multicomponent system composed of a solid active pharmaceutical ingredient (API)…

Studi Literatur Pengembangan Liposom Sebagai Brain Targeting Drug Delivery System (BTDDS) Open

Almirah Azis, Aulia Fikri Hidayat, Sani Ega Priani · 2024

The development of methods to improve drug delivery used in life-threatening diseases such as cancer and viral infections is urgently needed today. One alternative to drug delivery to the brain is to use a transport system or carrier desig…

EXPLORING THE DIVERSE PHYTOCHEMICALS AND POTENT ANTIOXIDANT PROPERTIES IN BEE HONEY Open

Taufik Muhammad Fakih, Lina Jamilah, Liza Dzulhijjah, Adryan Fristiohady, Jajang Japar Sodik , et al. · 2024

Honey cultivation in the Bandung Regency area has been growing. However, it has not been equipped with scientific data regarding the characteristics of several types of cultivated honey. The study aims to ascertain the physicochemical char…

Identifikasi Struktur Protein Spike Varian Baru SARS-CoV-2 secara Bioinformatika dalam Pengembangan Kandidat Terapi COVID-19 Open

Taufik Muhammad Fakih, Dwi Syah Fitra Ramadhan, Aulia Fikri Hidayat, Budi Prabowo Soewondo · 2023

Despite the relatively slow evolutionary rate of SARS-CoV-2 in comparison to other RNA viruses, the extensive and rapid transmission during the COVID-19 pandemic has led to the emergence of significant genetic diversity since the virus fir…

Analisis, pengembangan, dan sertifikasi produk madu trigona hasil budidaya masyarakat Open

Taufik Muhammad Fakih, Aulia Fikri Hidayat, Budi Prabowo Soewondo, Gita Cahya Eka Darma, Rizki Nuzulfikri , et al. · 2023

Permasalahan pokok yang dihadapi oleh Desa Tenjolaya, yang menjadi mitra dalam Program Pengembangan Produk Unggulan Mitra (P3UM), melibatkan tantangan terkait praktik budi daya lebah madu serta mendapatkan Sertifikat Produksi Pangan Indust…

Uji Aktivitas Antioksidan Kopi Arabika (Coffea arabica) Papandayan dan Gunung Halu Open

Nabila Shofura Mahardhika, Taufik Muhammad Fakih, Aulia Fikri Hidayat · 2023

Kopi merupakan minuman yang populer di kalangan masyarakat Indonesia di seluruh dunia karena memiliki rasa dan cita rasa yang khas serta bermanfaat bagi kesehatan. Kopi mengandung antioksidan yang salah satunya berasal dari senyawa fenolik…

Kajian Potensi Pengaruh Penerapan Teknologi Plasma Terhadap Efektivitas Ketercampuran Sistem Emulsifikasi Open

E Nurul Kholisoh Febriani, Gita Cahya Eka Darma, Aulia Fikri Hidayat · 2023

A formulator often faces challenges in formulating pharmaceutical preparations, especially emulsion preparations. The classic problem of making emulsion preparations which are difficult to mix is a challenge in itself. With these condition…

FORMULASI DAN KARAKTERISASI SISTEM NIOSOM ETIL VITAMIN C Open

Ratu Nabila Afriandini, Aulia Fikri Hidayat, Ratih Aryani · 2023

Abstrak. Etil vitamin C merupakan salah satu senyawa turunan vitamin C yang memiliki stabilitas yang lebih baik di banding turunan lainnya, yang memiliki fungsi sebagai whitening agent. Namun senyawa etil vitamin C diketahui sulit berpenen…

Studi Literatur Pengaplikasian Carbon Dots (CD) Sebagai Sistem Penghantaran Obat Terapi Kanker Open

Nur Hamida, Aulia Fikri Hidayat, Gita Cahya Eka Darma · 2023

Abstrak. Carbon dots (CD) merupakan salah satu sistem penghantaran obat berbasis karbon yang menarik perhatian dibidang nanoteknologi terutama pengaplikasiannya pada terapi kanker karena biokompatibilitas yang baik dan sitotoksisitasnya ya…

Pembentukan Kokristal Sebagai Upaya Peningkatan Kelarutan dan Laju Disolusi Obat BCS Kelas II Open

Silvi Sandi Putri, Fitrianti Darusman, Aulia Fikri Hidayat · 2023

Solubility is one of the critical physicochemical properties in drug absorption. Co-crystallization is an effort to increase the solubility and dissolution rate of active pharmaceutical ingredients with low solubility. This review article …

Pelatihan Diversifikasi Produk Madu di Kecamatan Pasirjambu, Kabupaten Bandung, Jawa Barat melalui Kolaborasi Luar Negeri dengan Thammasat University Open

Taufik Muhammad Fakih, Lina Jamilah, Liza Dzulhijjah, Adryan Fristiohady, Aulia Fikri Hidayat , et al. · 2023

The main problems found in the Malaya Farmer Group in Pasirjambu District which are partners, are problems related to honey bee harvesting techniques and the diversification of honey products. Some of the methods applied to achieve the tar…

Development and Characterization of Mefenamic Acid-Nicotinamide Nano-Cocrystal Open

Aulia Fikri Hidayat, Larasati Sofiyandini, Fitrianti Darusman · 2023

Oxidative Stability of Nano-Encapsulated Candlenut Oil Open

Aulia Fikri Hidayat, Ratih Aryani, Ratu Choesrina, Iin Dian Novita, Anggi Meliana Devi · 2022

Candlenut has a lot of potential pharmacological benefits including in hair care, in treating skin problems such as psoriasis, and in its use as an emollient. However, the high unsaturated fatty acid content of candlenut oil causes it to b…

Kajian Pengembangan Sistem Nanokapsul untuk Senyawa Flavonoid yang Memiliki Aktivitas Antioksidan Open

Farha Fadila, Aulia Fikri Hidayat, Ratih Aryani · 2022

The clinical use of flavonoid compounds is limited because their activity decreases during storage which is influenced by temperature, light, pH and oxygen. The nanocapsule system can be chosen to protect the compound from being rapidly de…

Identifikasi Epitop Sel-T COVID-19 terhadap Reseptor Imun TLR-2 (Toll-like Receptor-2) untuk Pengembangan Vaksin Berbasis Peptida Open

Ridwan Wijaya, Aulia Fikri Hidayat, Taufik Muhammad Fakih · 2022

The coronavirus outbreak that is sweeping the world is a serious challenge for the international health system. Overcoming the lack of information regarding experimental data, tools and even understanding of the body's immune response to S…

Formulasi dan Karakterisasi Transfersom Andrografolid Open

Syafanisa Alifia Rahma, Aulia Fikri Hidayat, Fitrianti Darusman · 2022

Andrographolide is the main bioactive compound in the sambiloto plant (Andrographis paniculata (Burm. f) Nees). Andrographolide is known to have poor solubility and low oral bioavailability. The transdermal route can be an alternative for …

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