Aurélie Fossey‐Jouenne
YOU?
Author Swipe
View article: Au/CaO as a highly active heterogeneous catalyst for aerobic oxidation of aliphatic alcohols in water-based mild conditions
Au/CaO as a highly active heterogeneous catalyst for aerobic oxidation of aliphatic alcohols in water-based mild conditions Open
The oxidation of alcohols to carboxylic acids is an important reaction in chemistry, which finds use in the production of pharmaceuticals, polymers, surfactants, cosmetics and textiles, to name a few. As an example, oxidation of 1,4-butane…
View article: Hybrid synthesis of AMFC-derived amides using supported gold nanoparticles and acyl-coenzyme A ligases
Hybrid synthesis of AMFC-derived amides using supported gold nanoparticles and acyl-coenzyme A ligases Open
By integrating different types of catalysts in the same system, hybrid catalysis emerges as an attractive and competitive approach. Within the framework of valorizing sustainably sourced bio-based products, we herein present a synthetic me…
View article: A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening
A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening Open
View article: Adapting an acyl CoA ligase from Metallosphaera sedula for lactam formation by structure-guided protein engineering
Adapting an acyl CoA ligase from Metallosphaera sedula for lactam formation by structure-guided protein engineering Open
The CoA ligase from Metallosphaera sedula ( Ms ACL) can be used for the chemoenzymatic synthesis of amides from carboxylic acids. In this CoA-independent conversion, the enzyme catalyzes the adenylation of a carboxylic acid with the help o…
View article: Sequence and HMM libraries
Sequence and HMM libraries Open
This repository contains the data specified in the paper entitled "A refined picture of the native Amine Dehydrogenase family revealed by extensive biodiversity screening". It includes: 1. NAD-dependent_enzymes.fa.gz - The library of 20,31…
View article: Sequence and HMM libraries
Sequence and HMM libraries Open
This repository contains the data specified in the paper entitled "A refined picture of the native Amine Dehydrogenase family revealed by extensive biodiversity screening". It includes: 1. NAD-dependent_enzymes.fa.gz - The library of 20,31…
View article: Native amine dehydrogenases can catalyze the direct reduction of carbonyl compounds to alcohols in the absence of ammonia
Native amine dehydrogenases can catalyze the direct reduction of carbonyl compounds to alcohols in the absence of ammonia Open
Native amine dehydrogenases (nat-AmDHs) catalyze the ( S )-stereoselective reductive amination of various ketones and aldehydes in the presence of high concentrations of ammonia. Based on the structure of Cfus AmDH from Cystobacter fuscus …
View article: Cover Feature: Expanding the Substrate Scope of Native Amine Dehydrogenases through <i>In Silico</i> Structural Exploration and Targeted Protein Engineering (ChemCatChem 22/2022)
Cover Feature: Expanding the Substrate Scope of Native Amine Dehydrogenases through <i>In Silico</i> Structural Exploration and Targeted Protein Engineering (ChemCatChem 22/2022) Open
The Cover Feature shows the active site of an amine dehydrogenase (AmDH), an enzyme which catalyzes the transformation of ketones into chiral amines. The protein has been modified by protein engineering, creating a variant that can synthes…
View article: Expanding the Substrate Scope of Native Amine Dehydrogenases through <i>In Silico</i> Structural Exploration and Targeted Protein Engineering
Expanding the Substrate Scope of Native Amine Dehydrogenases through <i>In Silico</i> Structural Exploration and Targeted Protein Engineering Open
Native Amine Dehydrogenases (nat‐AmDHs) are NAD(P)H‐enzymes performing reductive amination, mainly active towards small aliphatic aldehydes and cyclic ketones, due to active site volumes limited by the presence of several bulky amino acids…
View article: Synthesis of Chiral Amines via a Bi‐Enzymatic Cascade Using an Ene‐Reductase and Amine Dehydrogenase
Synthesis of Chiral Amines via a Bi‐Enzymatic Cascade Using an Ene‐Reductase and Amine Dehydrogenase Open
Access to chiral amines with more than one stereocentre remains challenging, although an increasing number of methods are emerging. Here we developed a proof‐of‐concept bi‐enzymatic cascade, consisting of an ene reductase and amine dehydro…
View article: XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii
XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii Open
View article: Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars
Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars Open
View article: Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine Open
Amino alcohols are versatile compounds with a wide range of applications. For instance, they have been used as chiral scaffolds in organic synthesis. Their synthesis by conventional organic chemistry often requires tedious multi-step synth…