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View article: Prevalence of oxalotrophy in the human microbiome
Prevalence of oxalotrophy in the human microbiome Open
While oxalotrophy is relatively uncommon, the broader capacity for oxalate degradation is more widespread. Notably, the genes frc and oxc are frequently found in close proximity within genomes, suggesting a selective advantage for organism…
View article: Chimeric Allergen Receptor regulatory T cells suppress birch pollen allergic airway inflammation.
Chimeric Allergen Receptor regulatory T cells suppress birch pollen allergic airway inflammation. Open
Asthma is a deadly chronic respiratory disease affecting over 300 million people. While allergen immunotherapy remains the only disease-modifying treatment, it is poorly applicable for patients with severe asthma. Here we explored the ther…
View article: Fighting <i>Aspergillus</i> infection using biocontrol bacteria: A proof-of-concept of environmental interference in a translational setting
Fighting <i>Aspergillus</i> infection using biocontrol bacteria: A proof-of-concept of environmental interference in a translational setting Open
Aspergillus fungi are opportunistic pathogens that affect millions of people worldwide. Aspergilli produce organic acids to optimize the environmental pH and match the needs of their enzymatic machinery. In this study, we tested the hypoth…
View article: Prevalence of Oxalotrophy in the Human Microbiome
Prevalence of Oxalotrophy in the Human Microbiome Open
Incomplete degradation of oxalate, a compound commonly found in the diet, can cause disease in humans, particularly of the kidney. Its concentration in the body depends on several factors, one of which is intestinal absorption, which is it…
View article: One-Step Soft Agar Enrichment and Isolation of Human Lung Bacteria Inhibiting the Germination of Aspergillus fumigatus Conidia
One-Step Soft Agar Enrichment and Isolation of Human Lung Bacteria Inhibiting the Germination of Aspergillus fumigatus Conidia Open
Fungi of the genus Aspergillus are widespread in the environment, where they produce large quantities of airborne conidia. Inhalation of Aspergillus spp. conidia in immunocompromised individuals can cause a wide spectrum of diseases, rangi…
View article: Use of a novel microbiome modulator improves anticancer immunity in a murine model of malignant pleural mesothelioma
Use of a novel microbiome modulator improves anticancer immunity in a murine model of malignant pleural mesothelioma Open
MMC administration boosts antitumor immunity, which correlates with a change in gut microbiome and metabolome. MMC may represent a valuable treatment option to combine with immunotherapy in patients with cancer.
View article: One-Step Soft Agar Enrichment and Isolation of Human Lung Bacteria Inhibiting the Germination of Aspergillus fumigatus conidia
One-Step Soft Agar Enrichment and Isolation of Human Lung Bacteria Inhibiting the Germination of Aspergillus fumigatus conidia Open
Fungi of the genus Aspergillus are widespread in the environment where they produce large quantities of airborne conidia. Inhalation of Aspergillus spp. conidia in immunocompromised individuals can cause a wide spectrum of diseases, rangin…
View article: Skin barrier immunology from early life to adulthood
Skin barrier immunology from early life to adulthood Open
View article: Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation
Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation Open
Barrier integrity is central to the maintenance of healthy immunological homeostasis. Impaired skin barrier function is linked with enhanced allergen sensitization and the development of diseases such as atopic dermatitis (AD), which can p…
View article: A BAFF/APRIL axis regulates obesogenic diet-driven weight gain
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain Open
View article: An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products
An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products Open
A helminth larval extract and its component Hpb glutamate dehydrogenase induce an anti-inflammatory mediator switch to suppress type-2 inflammation.
View article: Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism Open