Explanipedia

Four-Step Framework for Valve-in-Valve Transcatheter Aortic Valve Replacement for Failed Surgical and Transcatheter Aortic Bioprostheses Open

Miloš Branković, Hassan Akram, Aisha Shabbir, Laith Alhuneafat, Abhishek Sharma · 2025

Transcatheter aortic valve replacement (TAVR), originally developed to treat native aortic valve disease, has become increasingly adopted in the valve-in-valve (ViV) setting to manage bioprosthetic valve dysfunction of both surgically impl…

An unstable knee with gross varus deformity treated with unconstrained total knee replacement with long tibial stem: a case report Open

Nikunj Agrawal, Charan Kumar Voonna, Sunil Sharma, Abhishek Sharma · 2025

Severe varus deformity of the knee poses a technical challenge in balancing the flexion and extension gaps. Bone defects are a challenging problem encountered with severe varus deformity of knee during primary total knee arthroplasty (TKA)…

SCAI/HRS technical review on transcatheter left atrial appendage occlusion Open

Edmond M. Cronin, Steven J. Filby, Michael E. Field, Chetan Huded, Julia H. Indik , et al. · 2025

SCAI/HRS Technical Review on Transcatheter Left Atrial Appendage Occlusion Open

Edmond M. Cronin, Steven J. Filby, Michael E. Field, Chetan Huded, Julia H. Indik , et al. · 2025

Topological quantum materials: kagome, chiral, and square-net frameworks Open

Abhishek Sharma, S. Chatterjee, Premakumar Yanda, Claudia Felser, Chandra Shekhar · 2025

Topological quantum materials have emerged as a frontier in condensed matter physics as well as in materials science, with intriguing electronic states that are robust to perturbations. Among the diverse structural motifs, kagome, chiral, …

Intracardiac Echocardiography to Guide Left Atrial Appendage Occlusion: An Update Open

Miloš Branković, Adamantios Tsangaris, Luka Petrovic, Abhishek Sharma · 2025

The left atrial appendage occlusion (LAAO) procedure is an important intervention for stroke prevention in patients with non-valvular atrial fibrillation who cannot tolerate anticoagulation. Accurate imaging is essential to guide and ensur…

Transcatheter Aortic Valve Implantation and Replacement: The Latest Advances and Prospects Open

Miloš Branković, Abhishek Sharma · 2025

Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of aortic stenosis, particularly in patients at high risk of adverse events for traditional open-heart surgery. Since the early 2000s, TAVR has evolved rapidly …

COVID-19 Stigma and Discrimination in a North Indian State: A Concurrent Mixed Method Study Open

Manmeet Kaur, P. V. M. Lakshmi, Abhishek Sharma, Vijin Pandara Purayil, Nandita Mathur , et al. · 2023

Summary We measured COVID-19-related stigma and discrimination and its drivers using a concurrent mixed-methods design in Punjab. The simple random sampling was used to select blocks, subcenters, and urban primary healthcenters from each o…

Monocyte Distribution Width (MDW) in Patients with COVID-19: An Indicator of Disease Severity Open

Praveen Sharma, Shano Naseem, Neelam Varma, Niranjan Khaire, Nishant Jindal , et al. · 2023

Transcatheter Aortic Valve Replacement for Aortic Valve Infective Endocarditis: A Systematic Review and Call for Action Open

Miloš Branković, Ashkan Hashemi, Julia Ansari, Abhishek Sharma · 2023

Is There an Obesity Paradox in Transcatheter Aortic Valve Replacement? Open

Carl J. Lavie, Abhishek Sharma, Jose Tafur Soto · 2022

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The Ongoing National Medical Staffing Crisis: Impacts on Care Delivery for Interventional Cardiologists Open

Robert F. Riley, Mirvat Alasnag, Wayne Batchelor, Abhishek Sharma, Evan Luse , et al. · 2022

We are currently facing an international health care staffing crisis. It extends to all aspects and members of the care delivery team, including both the hospital and ambulatory settings. The COVID-19 pandemic exacerbated this crisis by cr…

E-Cigarettes and myocardial Infarction: a systemic review and meta-analysis Open

Abhishek Sharma, Ishita Gupta, Venkateswara Prasad U., Reshma Golamari · 2021

Funding Acknowledgements Type of funding sources: None. Introduction With widespread awareness about the harmful effects of traditional smoking, many people are considering the use of an e-cigarette. However, there are many studies which h…

Association of Renin-Angiotensin System Blockers With Outcomes in Patients with COVID-19 Open

Aakash Garg, Amit Rout, Abhishek Sharma, Brittany Fiorello, John B. Kostis · 2020

A Review of Various Methods for Prevention of Pressor Response to Intubation Open

Neha Bhardwaj, Abhishake Thakur, Abhishek Sharma · 2020

Endotracheal intubation has become an integral component of airway management. Intubation is associated with sympathetic surge leading to tachycardia and hypertension. Although these sympathetic responses following intubation are brief, th…

Comparative Study between Crystalloid Preloading and Coloading for Prevention of Hypotension in Elective Cesarean Section Under Spinal Anesthesia in a Secondary Care Hospital Open

Neha Bhardwaj, Abhishake Thakur, Abhishek Sharma · 2020

The anesthesia of choice for majority of elective cesarean deliveries is spinal anesthesia, as it is easier to administer, quicker in action, lesser cost, less risk of anesthetic toxicity, minimum transfer of drug to the fetus and provides…

Clinical Characteristics and In-Hospital Mortality for COVID-19 Across The Globe Open

Sunny Goel, Tarun Jain, Amit Hooda, Rohit Malhotra, Gurpreet Johal , et al. · 2020

There is a significant variation in the clinical characteristics in patients diagnosed with COVID-19 across the globe. In-hospital mortality is similar between America and Europe, but considerably higher than Asia.

Association of Obesity With More Critical Illness in COVID-19 Open

Abhishek Sharma, Akash Garg, Amit Rout, Carl J. Lavie · 2020

Association of Renin Angiotensin System Blockers with Outcomes in Patients with Covid-19: A Systematic Review and Meta-analysis Open

Aakash Garg, Amit Rout, Abhishek Sharma, Brittany Fiorello, John B. Kostis · 2020

Background Patients with cardiovascular disease are at increased risk of critical illness and mortality from Covid-19 disease. Conflicting findings have raised concerns regarding the association of angiotensin converting enzyme inhibitors …

COVID-19 pandemic and its impact on cardiology and its subspecialty training Open

Sunny Goel, Abhishek Sharma · 2020

Mitraclip Plus Medical Therapy Versus Medical Therapy Alone for Functional Mitral Regurgitation: A Meta-Analysis Open

Sunny Goel, Ravi Teja Pasam, Karan Wats, Srilekha Chava, Joseph Gotesman , et al. · 2019

Association between left ventricular function and severity of chronic obstructive pulmonary disease Open

Abhishek Sharma, Yogesh Mani Tripathi, Rinku Garg, Berendra Yadav · 2019

Meta-analysis of double-blind placebo control trials evaluating the role of coenzyme Q10 on semen parameters Open

Anuj Agarwal, Abhishek Sharma, K. Master, Ratti Ram Sharma, Ralf Henkel · 2018

Erythropoietin therapy after out-of-hospital cardiac arrest: A systematic review and meta-analysis Open

Rahul Chaudhary, Jalaj Garg, Parasuram Krishnamoorthy, Kevin Bliden, Neeraj Shah , et al. · 2017

Our study demonstrates no improvement in neurological outcomes and increased incidence of thrombotic events and acute coronary stent thrombosis in OHCA patients who were treated with Epo in addition to standard therapy.

Bioresorbable Coronary Scaffolds: Current State of Evidence Open

Sunny Goel, Shiv Raj, Abhishek Sharma, Umesh Gidwani, Robert Frankel , et al. · 2017

Second-generation drug-eluting stents are currently considered the standard of care in patients undergoing treatment for coronary artery disease with percutaneous coronary intervention. Despite significant improvements in stenting technolo…

Obesity paradox in patients undergoing coronary intervention: A review Open

Nirav Patel, Ossama Elsaid, Abhishek Shenoy, Abhishek Sharma, Samy I. McFarlane · 2017

There is strong relationship exist between obesity and cardiovascular disease including coronary artery disease (CAD). However, better outcomes noted in obese patients undergoing percutaneous cardiovascular interventions for CAD, a phenome…

Changes in parameters of right ventricular function with cardiac resynchronization therapy Open

Abhishek Sharma, Carl J. Lavie, Ajay Vallakati, Akash Garg, Sunny Goel , et al. · 2017

Background Studies have shown that cardiac resynchronization therapy (CRT) significantly improves right ventricle (RV) size and function in patients with heart failure (HF). Hypothesis CRT does not lead to improvement in RV function indepe…

The Reply Open

Aakash Garg, Abhishek Sharma · 2017

Duration of dual antiplatelet therapy following drug‐eluting stent implantation: A systemic review and meta‐analysis of randomized controlled trials with longer follow up Open

Abhishek Sharma, Sahil Agrawal, Aakash Garg, Ajay Vallakati, Carl J. Lavie , et al. · 2017

Objective To evaluate the long term efficacy and safety of long duration DAPT (L‐DAPT) compared to short duration DAPT (S‐DAPT) after drug‐eluting stent (DES) implantation. Methods We searched Medline, Embase, and Cochrane Central Register…

‘Optimized’ LV only pacing using a dual chamber pacemaker as a cost effective alternative to CRT Open

K. Maneesh, Mukund A. Prabhu, Abhishek Sharma, Ritesh Vekariya, Padmanabh Kamath , et al. · 2017

Optimized LVOP using 2D strain and ECG can be a cost-effective alternative to CRT in patients with LBBB, heart failure and normal AV node conduction.

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