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View article: Profiling of <i>Burkholderia pseudomallei</i> variants derived from Queensland’s clinical isolates
Profiling of <i>Burkholderia pseudomallei</i> variants derived from Queensland’s clinical isolates Open
Burkholderia pseudomallei ( Bp ), an environmental bacterium and opportunistic pathogen endemic to tropical regions, is highly adaptive and thrives in diverse environments, from soil to human hosts. Bacterial adaptation is critical for sur…
View article: Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland
Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland Open
While investigating colony morphology variation within clinical isolates of Burkholderia pseudomallei ( Bp) isolated from a single clinical infection, we identified two distinct strains (based on their multi-locus sequence type) from Bp TS…
View article: Co-isolation of genetically distinct <i>Burkholderia pseudomallei</i> strains from a single patient in North Queensland
Co-isolation of genetically distinct <i>Burkholderia pseudomallei</i> strains from a single patient in North Queensland Open
While investigating colony morphology variation (CMV) within clinical isolates of Burkholderia pseudomallei ( Bp ) isolated from a single infection, we identified two distinct strains (based on their multi-locus sequence type) from Bp TSV2…
View article: Profiling of <i>Burkholderia pseudomallei</i> variants derived from Queensland’s clinical isolates
Profiling of <i>Burkholderia pseudomallei</i> variants derived from Queensland’s clinical isolates Open
Burkholderia pseudomallei ( Bp ), an environmental bacterium and opportunistic pathogen endemic to tropical regions, is highly adaptive and thrives in diverse environments, from soil to human hosts. Bacterial adaptation is critical for sur…
View article: Gut Symptoms, Gut Dysbiosis and Gut-Derived Toxins in ALS
Gut Symptoms, Gut Dysbiosis and Gut-Derived Toxins in ALS Open
Many pathogenetic mechanisms have been proposed for amyotrophic lateral sclerosis (ALS). Recently, there have been emerging suggestions of a possible role for the gut microbiota. Gut microbiota have a range of functions and could influence…
View article: Elevated Levels of Homocysteinesulfinic Acid in the Plasma of Patients with Amyotrophic Lateral Sclerosis: A Potential Source of Excitotoxicity?
Elevated Levels of Homocysteinesulfinic Acid in the Plasma of Patients with Amyotrophic Lateral Sclerosis: A Potential Source of Excitotoxicity? Open
Objectives: Excitotoxicity is thought to be involved in the pathogenesis of amyotrophic lateral sclerosis (ALS). One possible source of excitotoxicity is the presence of sulphur amino acids (SAAs). In the brain of subjects with ALS, there …
View article: Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls
Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls Open
In amyotrophic lateral sclerosis, there is a need for biomarkers to distinguish patients from controls, to follow disease progression and to provide information about the pathogenesis of disease. In a previous mass spectrometry study that …
View article: Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects
Mass spectrometry analysis of plasma from amyotrophic lateral sclerosis and control subjects Open
Mass spectrometry was used to study blood samples from patients with amyotrophic lateral sclerosis (ALS) and healthy controls. Addenbrooke’s cognitive examination-III (ACE-III) was used to test for cognitive impairment (CI). Nano liquid ch…