Avinash Gadala
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View article: Multicenter evaluation of blood culture contamination and blood cultures practices in US acute care hospitals: time for standardization
Multicenter evaluation of blood culture contamination and blood cultures practices in US acute care hospitals: time for standardization Open
Clinical and Laboratory Standards Institute (CLSI) recommends a blood culture contamination (BCC) threshold of <3%, with ≤1% considered optimal. However, there is not a standardized definition of BCC, and the effect of multiple definitions…
View article: Blood Culture Use in Medical and Surgical Intensive Care Units and Wards
Blood Culture Use in Medical and Surgical Intensive Care Units and Wards Open
Importance Blood culture (BC) use benchmarks in US hospitals have not been defined. Objective To characterize BC use in adult intensive care units (ICUs) and wards in US hospitals. Design, Setting, and Participants A retrospective cross-se…
View article: CLABSIs aren’t just for inpatients: the need to identify CLABSI burden among outpatients
CLABSIs aren’t just for inpatients: the need to identify CLABSI burden among outpatients Open
View article: 2430. Risk Factors for Mortality among Patients who Present from the Community with Central Line-Associated Bloodstream Infections
2430. Risk Factors for Mortality among Patients who Present from the Community with Central Line-Associated Bloodstream Infections Open
Background Central line-associated bloodstream infections (CLABSI) lead to significant morbidity and mortality. Surveillance has contributed to reductions in the CLABSI rate in acute care hospitals. Although there are increasing numbers of…
View article: 2417. Epidemiology of Central Line-Associated Bloodstream Infections Present on Hospital Admission: A Multicenter Study
2417. Epidemiology of Central Line-Associated Bloodstream Infections Present on Hospital Admission: A Multicenter Study Open
Background National estimates of central line-associated bloodstream infections (CLABSI) focus on acute care hospital settings. Little is known about CLABSI that develop outside of hospitals and are present on admission (CLABSI-POA). We ai…
View article: Association of healthcare worker behaviors with coronavirus disease 2019 (COVID-19) risk during four pandemic periods and characteristics associated with high-risk behaviors
Association of healthcare worker behaviors with coronavirus disease 2019 (COVID-19) risk during four pandemic periods and characteristics associated with high-risk behaviors Open
In a large healthcare worker cohort, we quantified the association between behaviors and risk of coronavirus disease 2019 (COVID-19) during different pandemic phases, adjusting for prior infection and vaccination. Individual characteristic…
View article: Trends in pediatric community-onset <i>Staphylococcus aureus</i> antibiotic susceptibilities over a five-year period in a multihospital health system
Trends in pediatric community-onset <i>Staphylococcus aureus</i> antibiotic susceptibilities over a five-year period in a multihospital health system Open
The epidemiology of community-onset Staphylococcus aureus infections is evolving. We performed a multihospital, retrospective study of pediatric community-onset S. aureus susceptibilities between 2015 and 2020. Oxacillin and clindamycin su…
View article: 561. Methicillin-Resistant <i>Staphylococcus aureus</i> is Decreasing in Community-Onset Pediatric Infections Treated at a Mid-Atlantic Health System
561. Methicillin-Resistant <i>Staphylococcus aureus</i> is Decreasing in Community-Onset Pediatric Infections Treated at a Mid-Atlantic Health System Open
Background Hospitalizations due to soft tissue methicillin resistant S. aureus (MRSA) infections are decreasing nationally. Analyzing trends in pediatric community-onset (CO) S. aureus infections is needed to inform empiric antibiotic sele…
View article: Neutralizing SARS-CoV-2 Spike Antibodies against Omicron in Paired Samples after Two or Three Doses of mRNA Vaccine
Neutralizing SARS-CoV-2 Spike Antibodies against Omicron in Paired Samples after Two or Three Doses of mRNA Vaccine Open
This study found little to no neutralizing capability following a 2-dose mRNA vaccine series against the omicron variant, and neutralizing capacity to any variant strain tested was lost by 8-months post 2-dose series. However, the mRNA boo…
View article: Creating a Safety Officer Program to Enhance Staff Safety During the Care of COVID-19 Patients
Creating a Safety Officer Program to Enhance Staff Safety During the Care of COVID-19 Patients Open
Staff safety is paramount when managing an infectious disease event. However, early data from the COVID-19 pandemic suggested that staff compliance with personal protective equipment and other safety protocols was poor. In response to pati…
View article: Durability of Spike Immunoglobin G Antibodies to SARS-CoV-2 Among Health Care Workers With Prior Infection
Durability of Spike Immunoglobin G Antibodies to SARS-CoV-2 Among Health Care Workers With Prior Infection Open
This cohort study examines the durability of spike antibodies to SARS-CoV-2 among a cohort of US health workers.
View article: Association of Vaccine Type and Prior SARS-CoV-2 Infection With Symptoms and Antibody Measurements Following Vaccination Among Health Care Workers
Association of Vaccine Type and Prior SARS-CoV-2 Infection With Symptoms and Antibody Measurements Following Vaccination Among Health Care Workers Open
This cohort study evaluates symptoms following vaccination and antibody measurements in hospital workers who received an mRNA SARS-CoV-2 vaccine and had prior SARS-CoV-2 infection.
View article: Impact of postnatal age on neonatal intensive care unit bloodstream infection reporting
Impact of postnatal age on neonatal intensive care unit bloodstream infection reporting Open
View article: A model to forecast central-line-associated bloodstream infection rates in acute care hospital units
A model to forecast central-line-associated bloodstream infection rates in acute care hospital units Open
Background:Approximately 250,000 CLABSIs occur in the U.S. each year, 80,000 in intensive care units, these infections are associated with over 28,000 deaths each year and cost over $2 billion1. CLABSI increases patient morbidity and morta…
View article: A Diagnostic Stewardship Intervention To Improve Blood Culture Use among Adult Nonneutropenic Inpatients: the DISTRIBUTE Study
A Diagnostic Stewardship Intervention To Improve Blood Culture Use among Adult Nonneutropenic Inpatients: the DISTRIBUTE Study Open
Interventions to optimize blood culture (BCx) practices in adult inpatients are limited. We conducted a before-after study evaluating the impact of a diagnostic stewardship program that aimed to optimize BCx use in a medical intensive care…
View article: ICE volume 40 issue 5 Cover and Front matter
ICE volume 40 issue 5 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: ICE volume 40 issue 4 Cover and Front matter
ICE volume 40 issue 4 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Predicting probability of perirectal colonization with carbapenem-resistant Enterobacteriaceae (CRE) and other carbapenem-resistant organisms (CROs) at hospital unit admission
Predicting probability of perirectal colonization with carbapenem-resistant Enterobacteriaceae (CRE) and other carbapenem-resistant organisms (CROs) at hospital unit admission Open
Background: Targeted screening for carbapenem-resistant organisms (CROs), including carbapenem-resistant Enterobacteriaceae (CRE) and carbapenemase-producing organisms (CPOs), remains limited; recent data suggest that existing policies mis…
View article: ICE volume 39 issue 3 Cover and Front matter
ICE volume 39 issue 3 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: National Healthcare Safety Network laboratory-identified Clostridium difficile event reporting: A need for diagnostic stewardship
National Healthcare Safety Network laboratory-identified Clostridium difficile event reporting: A need for diagnostic stewardship Open
View article: The Role of Negative Methicillin-Resistant Staphylococcus aureus Nasal Surveillance Swabs in Predicting the Need for Empiric Vancomycin Therapy
The Role of Negative Methicillin-Resistant Staphylococcus aureus Nasal Surveillance Swabs in Predicting the Need for Empiric Vancomycin Therapy Open
Background The role of MRSA nasal surveillance swabs in guiding decisions about need for subsequent vancomycin therapy is unclear. Our objectives were to (1) determine the likelihood that patients with negative MRSA nasal swabs went on to …
View article: Clostridium difficile Laboratory Identification Event Reporting – A Need for Diagnostic Stewardship
Clostridium difficile Laboratory Identification Event Reporting – A Need for Diagnostic Stewardship Open
Background Clostridium difficile LabID event reporting uses electronic laboratory results without chart review. Nucleic acid amplification testing is common in the US. A positive result may represent colonization or C. diff infection (CDI)…