Avril Swarts
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View article: Risk factors for incident human immunodeficiency virus infection in South African blood donors
Risk factors for incident human immunodeficiency virus infection in South African blood donors Open
Background and Objectives Recruiting blood donors among a population with a high human immunodeficiency virus (HIV) burden requires detailed information on HIV risks. We studied demographic and behavioural risk factors for incident HIV inf…
View article: Xpert human papillomavirus test is a promising cervical cancer screening test for HIV-seropositive women
Xpert human papillomavirus test is a promising cervical cancer screening test for HIV-seropositive women Open
View article: Performance of the Cellslide® automated liquid-based cytology system amongst HIV-positive women
Performance of the Cellslide® automated liquid-based cytology system amongst HIV-positive women Open
Background: Many women undergoing cervical screening as part of a national South African screening programme may be positive for HIV. The performance of liquid-based cytology (LBC) on samples from HIV-positive women needs to be determined.…
View article: Awareness, perceived risk and practices related to cervical cancer and pap smear screening: A crosssectional study among HIV-positive women attending an urban HIV clinic in Johannesburg, South Africa
Awareness, perceived risk and practices related to cervical cancer and pap smear screening: A crosssectional study among HIV-positive women attending an urban HIV clinic in Johannesburg, South Africa Open
Background. Cervical cancer is a major cause of cancer-related deaths, especially in the context of the HIV epidemic. Objective. To examine awareness, perceived risk and practices related to cervical cancer screening among HIV-positive wom…
View article: A pooled analysis to compare the clinical characteristics of human papillomavirus–positive and -negative cervical precancers
A pooled analysis to compare the clinical characteristics of human papillomavirus–positive and -negative cervical precancers Open
Given that high-risk human papillomavirus (HPV) is the necessary cause of virtually all cervical cancer, the clinical meaning of HPV-negative cervical precancer is unknown. We, therefore, conducted a literature search in Ovid MEDLINE, PubM…
View article: Prevalence of Anal HPV and Anal Dysplasia in HIV-Infected Women from Johannesburg, South Africa
Prevalence of Anal HPV and Anal Dysplasia in HIV-Infected Women from Johannesburg, South Africa Open
Background: Anal cancer is a relatively common cancer among HIV-infected populations. There are limited data on the prevalence of anal high-risk human papillomavirus (HR-HPV) infection and anal dysplasia in HIV-infected women from resource…
View article: Prevalence of Anal Human Papillomavirus (HPV) and Performance of Cepheid Xpert and Hybrid Capture 2 (hc2) HPV Assays in South African HIV-Infected Women
Prevalence of Anal Human Papillomavirus (HPV) and Performance of Cepheid Xpert and Hybrid Capture 2 (hc2) HPV Assays in South African HIV-Infected Women Open
Objectives This study investigated anal high-risk HPV (HR-HPV) prevalence in HIV-infected women using the Cepheid Xpert HPV assay and compares its performance with that of Hybrid Capture-2 (hc2). Methods A total of 199 HIV-infected women w…
View article: A randomized clinical trial comparing cervical dysplasia treatment with cryotherapy vs loop electrosurgical excision procedure in HIV-seropositive women from Johannesburg, South Africa
A randomized clinical trial comparing cervical dysplasia treatment with cryotherapy vs loop electrosurgical excision procedure in HIV-seropositive women from Johannesburg, South Africa Open
Background Mortality associated with cervical cancer is a public health concern for women, particularly in HIV–seropositive women in resource-limited countries. HIV-seropositive women are at a higher risk of high-grade cervical precancer, …
View article: Data from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers
Data from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers Open
Given that high-risk human papillomavirus (HPV) is the necessary cause of virtually all cervical cancer, the clinical meaning of HPV-negative cervical precancer is unknown. We, therefore, conducted a literature search in Ovid MEDLINE, PubM…
View article: Supplemental Figures 1-2 from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers
Supplemental Figures 1-2 from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers Open
Supplemental Figures 1-2
View article: Supplemental Figures 1-2 from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers
Supplemental Figures 1-2 from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers Open
Supplemental Figures 1-2
View article: Supplementary Data Legends from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers
Supplementary Data Legends from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers Open
Supplementary Data Legends
View article: Data from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers
Data from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers Open
Given that high-risk human papillomavirus (HPV) is the necessary cause of virtually all cervical cancer, the clinical meaning of HPV-negative cervical precancer is unknown. We, therefore, conducted a literature search in Ovid MEDLINE, PubM…
View article: Supplementary Data Legends from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers
Supplementary Data Legends from A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers Open
Supplementary Data Legends
View article: Estimates of prevalence of anti-SARS-CoV-2 antibodies among blood donors in South Africa in March 2022
Estimates of prevalence of anti-SARS-CoV-2 antibodies among blood donors in South Africa in March 2022 Open
In line with previous instalments of analysis from this ongoing study to monitor ‘Covid Seroprevalence’ among blood donors in South Africa, we report on an analysis of 3395 samples obtained in mid-March 2022 from all provinces of South Afr…
View article: Estimates of prevalence of anti-SARS-CoV-2 antibodies among blood donors in South Africa in March 2022
Estimates of prevalence of anti-SARS-CoV-2 antibodies among blood donors in South Africa in March 2022 Open
View article: Convalescent plasma in the treatment of moderate to severe COVID-19 pneumonia: a randomized controlled trial (PROTECT-Patient Trial)
Convalescent plasma in the treatment of moderate to severe COVID-19 pneumonia: a randomized controlled trial (PROTECT-Patient Trial) Open
View article: Estimates of prevalence of anti-SARS-CoV-2 antibodies among blood donors in eight provinces of South Africa in November 2021
Estimates of prevalence of anti-SARS-CoV-2 antibodies among blood donors in eight provinces of South Africa in November 2021 Open
In line with previous instalments of analysis from this ongoing study to monitor ‘Covid Seroprevalence’ among blood donors in South Africa, we report on analysis of 3395 samples obtained from 8 to 12 November 2021 in all provinces of South…
View article: Rapid and Successful Implementation of a COVID-19 Convalescent Plasma Programme—The South African Experience
Rapid and Successful Implementation of a COVID-19 Convalescent Plasma Programme—The South African Experience Open
Background: COVID-19 convalescent plasma (CCP) has been considered internationally as a treatment option for COVID-19. CCP refers to plasma collected from donors who have recovered from and made antibodies to SARS-CoV-2. To date, convalesc…
View article: Validation of Cervical Cancer Screening Methods in HIV Positive Women from Johannesburg South Africa
Validation of Cervical Cancer Screening Methods in HIV Positive Women from Johannesburg South Africa Open
BackgroundHIV-infected women are at increased risk for developing cervical cancer. Women living in resource-limited countries are especially at risk due to poor access to cervical cancer screening and treatment. We evaluated three cervical…
View article: Evaluation of a Cervicography-Based Program to Ensure Quality of Visual Inspection of the Cervix in HIV-Infected Women in Johannesburg, South Africa
Evaluation of a Cervicography-Based Program to Ensure Quality of Visual Inspection of the Cervix in HIV-Infected Women in Johannesburg, South Africa Open
Quality assurance with cervicography and specialist review significantly improved the sensitivity of visual inspection with acetic acid to detect cervical intraepithelial neoplasia grade 2 or worse.AbstractObjectiveTo determine whether a q…
View article: Human Papillomavirus Vaccination Prior to Loop Electroexcision Procedure Does Not Prevent Recurrent Cervical High-grade Squamous Intraepithelial Lesions in Women Living With Human Immunodeficiency Virus: A Randomized, Double-blind, Placebo-controlled Trial
Human Papillomavirus Vaccination Prior to Loop Electroexcision Procedure Does Not Prevent Recurrent Cervical High-grade Squamous Intraepithelial Lesions in Women Living With Human Immunodeficiency Virus: A Randomized, Double-blind, Placebo-controlled Trial Open
Background Women living with human immunodeficiency virus (HIV), especially in sub-Saharan Africa, are at high risk for cervical high-grade squamous intraepithelial lesions (HSIL) and cervical cancer. These women have high HSIL recurrence …
View article: A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers
A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers Open
Given that high-risk human papillomavirus (HPV) is the necessary cause of virtually all cervical cancer, the clinical meaning of HPV-negative cervical precancer is unknown. We, therefore, conducted a literature search in Ovid MEDLINE, PubM…
View article: Prospective One Year Follow Up of HIV Infected Women Screened for Cervical Cancer Using Visual Inspection with Acetic Acid, Cytology and Human Papillomavirus Testing in Johannesburg South Africa
Prospective One Year Follow Up of HIV Infected Women Screened for Cervical Cancer Using Visual Inspection with Acetic Acid, Cytology and Human Papillomavirus Testing in Johannesburg South Africa Open
BackgroundCervical cancer is the most common cancer in Sub-Saharan Africa. There are little of HIV-infected women one-year after screening using visual inspection with acetic acid (VIA), HPV or cytology in sub-Saharan Africa.MethodsHIV-inf…
View article: Estimating the burden of cervical disease among HIV-infected women accessing screening services in South Africa: A model-based analysis
Estimating the burden of cervical disease among HIV-infected women accessing screening services in South Africa: A model-based analysis Open
Background. Cervical cancer remains the second most common cancer among women worldwide, with much of the global burden occurring in low- and middle-income countries. HIV-infected women are at increased risk of human papillomavirus infecti…
View article: Estimating the burden of cervical disease among HIV-infected women accessing screening services in South Africa: A model-based analysis
Estimating the burden of cervical disease among HIV-infected women accessing screening services in South Africa: A model-based analysis Open
Our findings highlight the magnitude of cervical disease among HIV-infected women in SA.
View article: Table of Contents
Table of Contents Open
View article: Prevalence of Anal Human Papillomavirus (HPV) and Performance of Cepheid Xpert and Hybrid Capture 2 (hc2) HPV Assays in South African HIV-Infected Women
Prevalence of Anal Human Papillomavirus (HPV) and Performance of Cepheid Xpert and Hybrid Capture 2 (hc2) HPV Assays in South African HIV-Infected Women Open
Xpert HPV typing is a promising anal screening test in HIV-infected women that performs similarly to hc2.
View article: Prevalence of Anal HPV and Anal Dysplasia in HIV-Infected Women From Johannesburg, South Africa
Prevalence of Anal HPV and Anal Dysplasia in HIV-Infected Women From Johannesburg, South Africa Open
Background: Anal cancer is a relatively common cancer among HIV-infected populations. There are limited data on the prevalence of anal high-risk human papillomavirus (HR-HPV) infection and anal dysplasia in HIV-infected women from resource…
View article: Awareness, perceived risk and practices related to cervical cancer and Pap smear screening: A cross-sectional study among HIV-positive women attending an urban HIV clinic in Johannesburg, South Africa
Awareness, perceived risk and practices related to cervical cancer and Pap smear screening: A cross-sectional study among HIV-positive women attending an urban HIV clinic in Johannesburg, South Africa Open
High levels of Pap smear awareness and low levels of Pap smear screening uptake were observed. However, Pap smear awareness was associated with adequate screening practice. More research into effective health education programmes to addres…