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View article: Supplementary Figures from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Figures from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
Figure S1 - S8, Table S1-S2
View article: Bronchial gene expression clustering in COPD identifies a subgroup of patients with higher level of bronchial T-cells and accelerated lung function decline
Bronchial gene expression clustering in COPD identifies a subgroup of patients with higher level of bronchial T-cells and accelerated lung function decline Open
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with varying degrees of airway wall thickening, chronic bronchitis, and emphysema. A better understanding of the underlying pathology is needed to improve the personal…
View article: An atlas of gene programs in non-small cell lung cancer delineates novel patterns of lineage vacillation, plasticity, and aggressiveness
An atlas of gene programs in non-small cell lung cancer delineates novel patterns of lineage vacillation, plasticity, and aggressiveness Open
Combinations of molecular programs can be altered in cancer cells and contribute to tumor initiation and aggressiveness. We developed a novel framework called a Gene Program Association Study (GPAS) to create an atlas of gene co-expression…
View article: Epithelial miR-149-5p up-regulation is associated with immune evasion in progressive bronchial premalignant lesions
Epithelial miR-149-5p up-regulation is associated with immune evasion in progressive bronchial premalignant lesions Open
The molecular drivers bronchial premalignant lesion progression to invasive lung squamous cell carcinoma are not well defined. Prior work profiling longitudinally collected bronchial premalignant lesion biopsies by RNA sequencing defined a…
View article: Supplementary Figures from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Figures from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
Figure S1 - S8, Table S1-S2
View article: Supplementary Table S4 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Table S4 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
DEGs between subsolid nodule and nLung C20 NKT cells
View article: Supplementary Table S5 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Table S5 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
DEGs between subsolid and nLung AT2 cells
View article: Supplementary Figures from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Figures from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
Figure S1 - S8, Table S1-S2
View article: Supplementary Table S5 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Table S5 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
DEGs between subsolid and nLung AT2 cells
View article: Supplementary Table S3 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Table S3 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
Summary of immune and non-immune cell clusters based on quality control metrics
View article: Data from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Data from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
A greater understanding of molecular, cellular, and immunological changes during the early stages of lung adenocarcinoma development could improve diagnostic and therapeutic approaches in patients with pulmonary nodules at risk for lung ca…
View article: Supplementary Table S4 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Table S4 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
DEGs between subsolid nodule and nLung C20 NKT cells
View article: Supplementary Table S3 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma
Supplementary Table S3 from Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma Open
Summary of immune and non-immune cell clusters based on quality control metrics
View article: The evolution of lung adenocarcinoma precursors is associated with chromosomal instability and transition from innate to adaptive immune response/evasion
The evolution of lung adenocarcinoma precursors is associated with chromosomal instability and transition from innate to adaptive immune response/evasion Open
View article: Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma
Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma Open
View article: An atlas of epithelial cell states and plasticity in lung adenocarcinoma
An atlas of epithelial cell states and plasticity in lung adenocarcinoma Open
Understanding the cellular processes that underlie early lung adenocarcinoma (LUAD) development is needed to devise intervention strategies 1 . Here we studied 246,102 single epithelial cells from 16 early-stage LUADs and 47 matched normal…
View article: Supplementary Table S4 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Table S4 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
DEGs between subsolid nodule and nLung C20 NKT cells
View article: Supplementary Figures from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Figures from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
Figure S1 - S8, Table S1-S2
View article: Supplementary Table S3 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Table S3 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
Summary of immune and non-immune cell clusters based on quality control metrics
View article: Supplementary Table S4 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Table S4 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
DEGs between subsolid nodule and nLung C20 NKT cells
View article: Data from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Data from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
A greater understanding of molecular, cellular, and immunological changes during the early stages of lung adenocarcinoma development could improve diagnostic and therapeutic approaches in patients with pulmonary nodules at risk for lung ca…
View article: Supplementary Table S3 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Table S3 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
Summary of immune and non-immune cell clusters based on quality control metrics
View article: Supplementary Figures from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Figures from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
Figure S1 - S8, Table S1-S2
View article: Supplementary Table S5 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Table S5 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
DEGs between subsolid and nLung AT2 cells
View article: Supplementary Table S5 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Supplementary Table S5 from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
DEGs between subsolid and nLung AT2 cells
View article: Data from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Data from Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
A greater understanding of molecular, cellular, and immunological changes during the early stages of lung adenocarcinoma development could improve diagnostic and therapeutic approaches in patients with pulmonary nodules at risk for lung ca…
View article: Integrative genetic and genomic networks identify microRNA associated with COPD and ILD
Integrative genetic and genomic networks identify microRNA associated with COPD and ILD Open
View article: Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer
Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer Open
Somatic mutations are a hallmark of tumorigenesis and may be useful for non-invasive diagnosis of cancer. We analyzed whole-genome sequencing data from 2,511 individuals in the Pan-Cancer Analysis of Whole Genomes (PCAWG) study as well as …
View article: Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma
Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma Open
A greater understanding of molecular, cellular, and immunological changes during the early stages of lung adenocarcinoma development could improve diagnostic and therapeutic approaches in patients with pulmonary nodules at risk for lung ca…
View article: Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression
Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression Open