Explanipedia

Perpendicular Vascular Changes in NBI-CE of Laryngeal Lesions: Diagnostic Accuracy, Reproducibility, and Common Pitfalls Open

Paul Pickert, Anja Giers, Anke Lux, Vasiliki-Anna Papaioannou, Nazila Esmaeili , et al. · 2025

Background/Objectives: Differentiating benign, premalignant, and early malignant vocal fold lesions is challenging. Perpendicular vascular changes (PVC) per the European Lar-yngological Society (ELS) are key malignancy indicators. Enhanced…

Development of a robotic test stand for testing vibroacoustic sensor units in needle insertion experiments Open

Yan Huang, Moritz Spiller, Ludwig Wermke, Axel Boese, Nazila Esmaeili , et al. · 2025

To ensure the quality of newly developed medical devices, rigorous testing is essential. Conventional manual testing is a time-consuming, costly, and non-standardized process. Therefore, automation and robotics play an important role. This…

Evaluation and feasibility of diagnostic heatflow imaging in patients with palpable breast lesions: a pilot study Open

Patrik Pöschke, Axel Boese, Katharina Seitz, Niklas Amann, Sophie Eckstein , et al. · 2025

Ex vivo differentiation of cartilage degeneration severity and subchondral bone using vibroacoustic signals from instrument-tissue-interaction Open

Thomas Sühn, Maximilian Costa, Nazila Esmaeili, Moritz Spiller, Axel Boese , et al. · 2025

Osteoarthritis (OA) of the knee is characterized by cartilage matrix degeneration, which eventually leads to joint dysfunction and surgical replacement. Preoperative radiography, the standard for treatment decision-making, provides limited…

Initial findings creating a temperature prediction model using vibroacoustic signals originating from tissue needle interactions Open

Michael Friebe, Witold Serwatka, Katharina Steeg, Gabriele A. Krombach, Hamza Oran , et al. · 2025

Exploring Deep Clustering Methods in Vibro-Acoustic Sensing for Enhancing Biological Tissue Characterization Open

Robin Urrutia, Diego Espejo, Montserrat Guerra, Karin Vío, Thomas Sühn , et al. · 2025

Nonlinear dimensionality reduction techniques, often referred to as manifold learning, are increasingly valuable for data visualization and unsupervised clustering. In the context of surgery and medicine, these methods facilitate the analy…

Temperature Prediction extracted from Tissue-Needle Vibroacoustic Signals: Initial Findings Open

Michael Friebe, Witold Serwatka, Katharina Steeg, Gabriele A. Krombach, Hamza Oran , et al. · 2024

Concept of a load reducing knee-orthosis Open

Abdallah Abdulrazeq, Ahmed Al-Hazba, Till Pöschel, Hanna Thomas, Axel Boese · 2024

Joint diseases are one of the significant challenges that come with age. The pain that these diseases cause can affect the quality of life of the patient, especially if the disease is causing aches in a high-load-bearing joint like the kne…

Assessing underlying pulsatile structures with laparoscopic tools using proximal vibroacoustic sensing Open

Syrine Kaabachi, Alfredo Illanes, Nazila Esmaeili, Thomas Sühn, Moritz Spiller , et al. · 2024

This work presents a novel approach for detecting underlying pulsatile structures with laparoscopic tools by using proximal vibroacoustic sensing. This new method could detect pulsations at a depth of up to 1.5 cm. The outcome of this work…

Variational Autoencoder feature clustering for tissue classification in robotic palpation Open

Robin Urrutia, Diego Espejo, Thomas Sühn, Montserrat Guerra, Patricio Fuentealba , et al. · 2024

Minimally Invasive Robotic Surgery (MIRS) has emerged as a transformative approach in surgical practice, offering reduced patient trauma and enhanced precision. However, challenges persist, including the loss of tactile feedback for surgeo…

Instrument Interactions as Source of Information in Robot-Assisted Surgery Open

Thomas Sühn, Moritz Spiller, Nazila Esmaeili, Maximilian Costa, Christoph H. Lohmann , et al. · 2024

The interaction between the surgical instrument and tissue is a yet little-exploited source of information. Vibroacoustic signals resulting from an interaction can be analyzed to extract relevant information related to the tissue. This wor…

Enhancing Veress Needle Entry with Proximal Vibroacoustic Sensing for Automatic Identification of Peritoneum Puncture Open

Moritz Spiller, Nazila Esmaeili, Thomas Sühn, Axel Boese, Salmai Turial , et al. · 2024

Laparoscopic access, a critical yet challenging step in surgical procedures, often leads to complications. Existing systems, such as improved Veress needles and optical trocars, offer limited safety benefits but come with elevated costs. I…

Personalized 3D Printed Patches for Fast and Safe Radiation Therapy of Non Melanoma Skin Cancer Open

Michael Friebe, Axel Boese, Castro Nathan J., Dietmar W. Hutmacher, Ali Pashazadeh · 2024

This study addresses the challenge of treating skin cancer effectively, especially in visible areas like the face, where traditional methods may be undesirable. Current options, including surgery and radiation therapy, have limitations suc…

Clustering Methods for Vibro-Acoustic Sensing Features as a Potential Approach to Tissue Characterisation in Robot-Assisted Interventions Open

Robin Urrutia, Diego Espejo, Natalia Evens, Montserrat Guerra, Thomas Sühn , et al. · 2023

This article provides a comprehensive analysis of the feature extraction methods applied to vibro-acoustic signals (VA signals) in the context of robot-assisted interventions. The primary objective is to extract valuable information from t…

Contact Endoscopy – Narrow Band Imaging (CE-NBI) data set for laryngeal lesion assessment Open

Nazila Esmaeili, Nikolaos Davaris, Axel Boese, Alfredo Illanes, Nassir Navab , et al. · 2023

Concept of a fully-implantable system to monitor tumor recurrence Open

Anna Schaufler, Ahmed Y. Sanin, I. Erol Sandalcioglu, Karl Hartmann, Roland S. Croner , et al. · 2023

Audio-based tissue classification - preliminary investigation for a needle procedure Open

Witold Serwatka, Katarzyna Heryan, Joanna Sorysz, Alfredo Illanes, Axel Boese , et al. · 2023

Image-guided and minimally invasive procedures still require confirmation on having reached a target. Intraoperative imaging is not always sufficient or conclusive as it comes with artifacts that can come with a certain amount of ambiguity…

Towards AI-driven minimally invasive needle interventions Open

Moritz Spiller, Nazila Esmaeili, Thomas Sühn, Axel Boese, Michael Friebe , et al. · 2023

The overall complication rate during laparoscopic access is estimated to be as high as 14 %. Surgeons have to rely heavily on their experience and haptic perception while inserting the Veress needle or a trocar into the peritoneal cavity. …

Conveyor-based robot allows fast and safe instrument handling in the operating room Open

Keisuke Yamashita, Cora Wex, Roland S. Croner, Axel Boese · 2023

According to [1]-[3], the healthcare systems are suffering from severe personnel shortages with a lack of medical care workers, operating room nurses, and surgical technicians. This deficiency will become worse in the upcoming decades. Aut…

Evaluation of flushing parameters for clear view vascular endoscopy Open

Julian Böckmann, Stefan Klebingat, Roland Schwab, Daniel Behme, Axel Boese · 2023

Vascular diseases like aneurysms or atherosclerosis belong to the leading causes of death. For diagnosis and treatment, medical imaging is essential. Standard imaging methods are Ultrasound, X-ray-based Angiography, Computed tomography or …

Laparoscopic surgery augmentation through vibro-acoustic sensing of instrument-tissue interactions Open

Nazila Esmaeili, Sophie Fischerauer, Thomas Sühn, Axel Boese, Jana Bußhoff , et al. · 2023

This paper presents the use of vibro-acoustic sensing to augment laparoscopic surgery procedures by analyzing the signals produced during cutting and palpation tasks on various tissue samples. Vibro-acoustic signals were acquired during an…

Vibro-acoustic sensing of tissue-instrument-interactions allows a differentiation of biological tissue in computerised palpation Open

Thomas Sühn, Nazila Esmaeili, Moritz Spiller, Maximilian Costa, Axel Boese , et al. · 2023

Simple features derived from the vibro-acoustic signals facilitate the differentiation between biological tissues, showing the potential of the presented approach to provide information related to the interacting tissue. The results encour…

Vibro-Acoustic Sensing of Instrument Interactions as a Potential Source of Texture-Related Information in Robotic Palpation Open

Thomas Sühn, Nazila Esmaeili, Sandeep Y. Mattepu, Moritz Spiller, Axel Boese , et al. · 2023

The direct tactile assessment of surface textures during palpation is an essential component of open surgery that is impeded in minimally invasive and robot-assisted surgery. When indirectly palpating with a surgical instrument, the struct…

Remote knee endoprosthesis monitoring – alignment requirements and prototyping of the external readout unit Open

Paul Rieck, Anna Schaufler, Holger Fritzsche, Jessica Bertrand, Christoph Lohmann , et al. · 2022

Knee arthroplasty follow-up involves only a limited number of X-ray-based implant condition assessments at extended intervals. Polyethylene (PE) wear of knee endoprosthesis often progresses unnoticed until symptomatic adverse effects becom…

A concept to combine a gamma probe with ultrasound imaging for improved localization of sentinel lymph nodes: a feasibility study of the concept Open

Ali Pashazadeh, Christoph Hoeschen, Oliver S. Großer, Michael C. Kreißl, Dennis Kupitz , et al. · 2022

This paper presents the proof-of-concept study of an adaptor allowing the combination of a gamma probe with ultrasound (US) imaging, intending to improve the detectability of sentinel lymph nodes (SLNs). The performance of the adaptor in U…

Concept for a retractor with force indicator for reduction of tissue trauma in abdominal surgery Open

Axel Boese, Roland S. Croner, Cora Wex · 2022

Retractors are used in surgery for the displacement of tissue and organs and to keep the surgical area open. The retraction can lead to a tissue compression that can cause irritation on nerves, perfusion deficits, hematoma or late sequelae…

Thyroid Nodule Region Estimation using Auto-Regressive Modelling and Machine Learning Open

Elmer Jeto Gomes Ataide, Mathews S. Jabaraj, Alfredo Illanes, Simone Schenke, Axel Boese , et al. · 2022

Ultrasound (US) imaging is used for the diagnosis and also evaluation of thyroid nodules. A Thyroid Imaging Reporting and Data System (TIRADS) is used for the risk stratification of thyroid nodules through US images. The composition of thy…

A new method for OCT Imaging of the Eustachian tube Open

Axel Boese, Holger Fritzsche, Gerrit Paasche, Thomas Lenarz, Robert Schuon · 2022

For treatment decision of Eustachian tube (ET) dysfunction, a reliable diagnosis of the reason for this dysfunction is of interest. Imaging methods like CT or MRI do not show enough details today. Endoscopy is challenging but can show at l…

Surgeons' requirements for a surgical support system to improve laparoscopic access Open

Moritz Spiller, Marcus Bruennel, Victoria Grosse, Thomas Sühn, Nazila Esmaeili , et al. · 2022

Contact Endoscopy – Narrow Band Imaging (CE-NBI) Data Set for Laryngeal Lesion Assessment Open

Nazila Esmaeili, Nikolaos Davaris, Axel Boese, Alfredo Illanes, Michael Friebe , et al. · 2022

The endoscopic examination of subepithelial vascular variations of vocal folds can provide complementary diagnostic information for clinicians regarding the development of benign and malignant laryngeal lesions. As one novel technique, Con…

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