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View article: MuSK cysteine-rich domain antibodies are pathogenic in a mouse model of autoimmune myasthenia gravis
MuSK cysteine-rich domain antibodies are pathogenic in a mouse model of autoimmune myasthenia gravis Open
The neuromuscular junction (NMJ), a synapse between the motor neuron terminal and a skeletal muscle fiber, is crucial throughout life in maintaining the reliable neurotransmission required for functional motricity. Disruption of this syste…
View article: Development of a refined experimental mouse model of myasthenia gravis with anti-acetylcholine receptor antibodies
Development of a refined experimental mouse model of myasthenia gravis with anti-acetylcholine receptor antibodies Open
Myasthenia gravis (MG) is an autoimmune disorder primarily caused by autoantibodies that target the acetylcholine receptor (AChR) at the neuromuscular junction (NMJ). The classical experimental autoimmune myasthenia gravis (C-EAMG) mouse m…
View article: Issue Information
Issue Information Open
Wiley is a founding member of the UN-backed HINARI, AGORA, and OARE initiatives.They are now collectively known as Research4Life, making online scientific content available free or at nominal cost to researchers in developing countries.
View article: Central Role of Macrophages and Nucleic Acid Release in Myasthenia Gravis Thymus
Central Role of Macrophages and Nucleic Acid Release in Myasthenia Gravis Thymus Open
Objective Myasthenia gravis (MG) is a neuromuscular disease mediated by antibodies against the acetylcholine receptor (AChR). The thymus plays a primary role in AChR‐MG and is characterized by a type I interferon (IFN) signature linked to …
View article: A new platform for autoimmune diseases. Inducing tolerance with liposomes encapsulating autoantigens
A new platform for autoimmune diseases. Inducing tolerance with liposomes encapsulating autoantigens Open
Autoimmune diseases (AIDs) are caused by the loss of self-tolerance and destruction of tissues by the host's immune system. Several antigen-specific immunotherapies, focused on arresting the autoimmune attack, have been tested in clinical …
View article: Myasthenia Gravis: An Acquired Interferonopathy?
Myasthenia Gravis: An Acquired Interferonopathy? Open
Myasthenia gravis (MG) is a rare autoimmune disease mediated by antibodies against components of the neuromuscular junction, particularly the acetylcholine receptor (AChR). The thymus plays a primary role in AChR-MG patients. In early-onse…