Aya Abe
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View article: Effects of Blackcurrant Extract and Partially Hydrolyzed Guar Gum Intake on Gut Dysbiosis in Male University Rugby Players
Effects of Blackcurrant Extract and Partially Hydrolyzed Guar Gum Intake on Gut Dysbiosis in Male University Rugby Players Open
Our previous study reported that male university rugby players tended to have a gut with a dysbiotic environment, characterized by abundant pathobiont bacteria and an accumulation of succinate, when compared with age-matched, non-rugby pla…
View article: Partially hydrolyzed guar gum ingestion suppresses atopic dermatitis-like symptoms through prebiotic effect in mice
Partially hydrolyzed guar gum ingestion suppresses atopic dermatitis-like symptoms through prebiotic effect in mice Open
Growing knowledge reveals the association between the gut microbiome and skin, rendering the gut microbiome an appealing potential therapeutic target for atopic dermatitis (AD). In this study, we assessed the effect of partially hydrolyzed…
View article: Are We Getting Closer to Consensus? An Analysis of Changes in Socially Perceived Necessities Over Time in Japan
Are We Getting Closer to Consensus? An Analysis of Changes in Socially Perceived Necessities Over Time in Japan Open
The measurement of poverty using the material deprivation scale has become widespread throughout the world. One of the technical challenges in constructing the material deprivation scale is the identification of socially perceived necessit…
View article: Partially hydrolyzed guar gum suppresses binge alcohol‐induced liver fat accumulation via gut environment modulation in mice
Partially hydrolyzed guar gum suppresses binge alcohol‐induced liver fat accumulation via gut environment modulation in mice Open
Alcohol‐associated liver disease (ALD), including alcoholic fatty liver, is a serious problem in many countries, and its economic costs to society are enormous. There is evidence indicating the relations between gut environments and liver …
View article: Synergistic effect of partially hydrolyzed guar gum on Clostridium butyricum in a synbiotic combination for enhanced butyrate production during in-vitro fermentation
Synergistic effect of partially hydrolyzed guar gum on Clostridium butyricum in a synbiotic combination for enhanced butyrate production during in-vitro fermentation Open
Background: Clostridium butyricum is a butyrate-producing beneficial bacterium and is generally recognized as a significant indicator of appropriate gut microbial metabolism in human health. Objective: The synergistic effects of commercial…
View article: Dietary intervention of prebiotic partially hydrolyzed guar gum improves skin viscoelasticity, stratum corneum hydration, and reduction of trans-epidermal water loss: a randomized, double-blind, and placebo-controlled clinical study in healthy humans
Dietary intervention of prebiotic partially hydrolyzed guar gum improves skin viscoelasticity, stratum corneum hydration, and reduction of trans-epidermal water loss: a randomized, double-blind, and placebo-controlled clinical study in healthy humans Open
Dietary fiber-rich diets are gaining popularity as an alternative therapy for skin health. Plant-based prebiotic partially hydrolyzed guar gum (PHGG) dietary fiber promotes gastrointestinal health, which is imperative for skin health throu…
View article: Effectiveness of Partially Hydrolyzed Guar Gum on Cognitive Function and Sleep Efficiency in Healthy Elderly Subjects in a Randomized, Double-Blind, Placebo-Controlled, and Parallel-Group Study
Effectiveness of Partially Hydrolyzed Guar Gum on Cognitive Function and Sleep Efficiency in Healthy Elderly Subjects in a Randomized, Double-Blind, Placebo-Controlled, and Parallel-Group Study Open
The consumption of functional foods in a daily diet is a promising approach for the maintenance of cognitive health. The present study examines the effects of water-soluble prebiotic dietary-fiber, partially hydrolyzed guar gum (PHGG), on …
View article: Safety evaluation of excessive intake of Hesperetin-7-Glucoside-β-Cyclodextrin Inclusion Complex in Healthy Japanese Subjects
Safety evaluation of excessive intake of Hesperetin-7-Glucoside-β-Cyclodextrin Inclusion Complex in Healthy Japanese Subjects Open
Background: Hesperidin, a flavonoid glycoside, is widely found in the peels and rinds of citrus fruits, offering various physiological benefits. However, its effectiveness is hindered by challenges related to insolubility and low bioavaila…
View article: Alleviating the physical discomfort in healthy individuals with Moringa seed extract: a randomized, double-blind, placebo-controlled, parallel-group trial
Alleviating the physical discomfort in healthy individuals with Moringa seed extract: a randomized, double-blind, placebo-controlled, parallel-group trial Open
Background: Moringa oleifera is well recognized for its rich nutritional content and diverse bioactive compounds. Moringa, abundant in various bioactive compounds such as flavonoids and alkaloids present across all plant parts including le…
View article: Hesperetin-7-O-glucoside/β-cyclodextrin Inclusion Complex Induces Acute Vasodilator Effect to Inhibit the Cold Sensation Response during Localized Cold-Stimulate Stress in Healthy Human Subjects: A Randomized, Double-Blind, Crossover, and Placebo-Controlled Study
Hesperetin-7-O-glucoside/β-cyclodextrin Inclusion Complex Induces Acute Vasodilator Effect to Inhibit the Cold Sensation Response during Localized Cold-Stimulate Stress in Healthy Human Subjects: A Randomized, Double-Blind, Crossover, and Placebo-Controlled Study Open
Hesperetin, a citrus flavonoid, exerts vasodilation and is expected to improve endothelial function and alleviate cold sensation by activating nervous system thermal transduction pathways. In this randomized, double-blind, crossover, and p…
View article: Improved bioavailability of hesperetin 7-O-glucoside inclusion complex with β-cyclodextrin in Sprague-Dawley rats and healthy humans
Improved bioavailability of hesperetin 7-O-glucoside inclusion complex with β-cyclodextrin in Sprague-Dawley rats and healthy humans Open
The flavonoid hesperidin and its aglycone are widely recognized for their functionality, wherein bioavailability is the key to ensuring their bio-efficacy for diverse health benefits. The aim of the present study was to evaluate the pharma…
View article: The effects of prebiotic partially hydrolyzed guar gum on skin hydration: A randomized, open-label, parallel, controlled study in healthy humans
The effects of prebiotic partially hydrolyzed guar gum on skin hydration: A randomized, open-label, parallel, controlled study in healthy humans Open
Dose-response of prebiotic partially hydrolyzed guar gum (PHGG) dietary fiber supports the gut microbiome abundance and improves gastrointestinal health, which is imperative for healthy skin. In this 12 week of open-label randomized, paral…
View article: Partially hydrolyzed guar gum is associated with improvement in gut health, sleep, and motivation among healthy subjects
Partially hydrolyzed guar gum is associated with improvement in gut health, sleep, and motivation among healthy subjects Open
Partially hydrolyzed guar gum dietary fiber is well recognized for a number of health benefits. In the present study, we aim to investigate the effects of partially hydrolyzed guar gum on constipation, intestinal microbiota as well as ment…
View article: Evaluation of Habitual Energy and Nutrient Intake in Children Attending Nursery Schools
Evaluation of Habitual Energy and Nutrient Intake in Children Attending Nursery Schools Open
2019年あるいは2020年の秋期に全国7都市の保育所に在籍する3‐6歳児の幼児798名を対象に, 連続しない平日2日と休日2日の計4日間, 秤量記録法による食事調査を実施した。平日と休日それぞれの習慣的な栄養素等摂取量を算出し, 日本人の食事摂取基準 (2020年版) の各指標の基準と比較し評価した。習慣的な栄養素摂取量が推定平均必要量 (EAR) 未満の割合が平日に比べて休日で有意に多かった栄養素はビタミンA, B1, B2, C, カリウム, カルシウム, 鉄であった…
View article: Working poverty and anti-poverty policy in four East Asian societies
Working poverty and anti-poverty policy in four East Asian societies Open
"Working poverty" occurs when market labor earnings plus post-market transfers together do not provide adequate resources to reach a minimal standard of living. This chapter overviews working poverty and social policy aimed to address it i…
View article: Income packaging and social safety nets for low-income families with children in East Asia
Income packaging and social safety nets for low-income families with children in East Asia Open
The welfare regimes in East Asia are traditionally characterized as productivist, where social policies are subordinated to economic development goals. However, many studies have suggested that welfare approaches adopted by East Asian coun…
View article: What makes old-age poverty in East Asian societies so high?
What makes old-age poverty in East Asian societies so high? Open
This study compares poverty among older adults in China, Japan, Korea, and Taiwan with that in selected Western societies and explores factors contributing to these high levels of poverty among older adults from a comparative perspective. …
View article: Structural Investigation of Hesperetin-7-O-Glucoside Inclusion Complex with β-Cyclodextrin: A Spectroscopic Assessment
Structural Investigation of Hesperetin-7-O-Glucoside Inclusion Complex with β-Cyclodextrin: A Spectroscopic Assessment Open
Flavonoids are biologically active natural products of great interest for their potential applications in functional foods and pharmaceuticals. A hesperetin-7-O-glucoside inclusion complex with β-cyclodextrin (HEPT7G/βCD; SunActive® HCD) w…
View article: Monocaprin Enhances Bioavailability of Fucoxanthin in Diabetic/Obese KK-Ay Mice
Monocaprin Enhances Bioavailability of Fucoxanthin in Diabetic/Obese KK-Ay Mice Open
Fucoxanthin is a marine carotenoid found in brown seaweeds and several microalgae. It has been reported that fucoxanthin has health benefits such as anti-obesity and anti-diabetic effects. To facilitate fucoxanthin applications in the food…
View article: Partially Hydrolyzed Guar Gum Suppresses the Development of Sarcopenic Obesity
Partially Hydrolyzed Guar Gum Suppresses the Development of Sarcopenic Obesity Open
Partially hydrolyzed guar gum (PHGG) is a soluble dietary fiber derived through controlled enzymatic hydrolysis of guar gum, a highly viscous galactomannan derived from the seeds of Cyamopsis tetragonoloba. Here, we examined the therapeuti…
View article: Water‐soluble dietary fiber alleviates cancer‐induced muscle wasting through changes in gut microenvironment in mice
Water‐soluble dietary fiber alleviates cancer‐induced muscle wasting through changes in gut microenvironment in mice Open
Cancer cachexia and the associated skeletal muscle wasting are considered poor prognostic factors, although effective treatment has not yet been established. Recent studies have indicated that the pathogenesis of skeletal muscle loss may i…
View article: Derivatized-imaging mass spectrometer revealed the effect of theanine for monoamine metabolism
Derivatized-imaging mass spectrometer revealed the effect of theanine for monoamine metabolism Open
L-Theanine (LTE) is a derivative of glutamic acid, which is abundant in tea leaves and contributes to the umami and sweetness of tea. In recent years, its effects on the brain, such as relaxation, have been attracting attention. In this st…
View article: The Effect of Programs to Reduce Health Care Cost for Children on Parental Behavior
The Effect of Programs to Reduce Health Care Cost for Children on Parental Behavior Open
本稿は，市区町村による子どもの医療費助成制度が，子どもの医療サービスの受診抑制に与える影響を，三つの都県の子どもの生活に関する調査を統合したデータを用いて推計したものである。本件で用いられたデータでは，子どもの居住する市区町村が判別できるため，医療サービスの自己負担が０円，定額（200～500円），３割（助成制度なし），償還払い（窓口は３割。後ほど定額負担以外が償還）の四つの制度に分類し，保護者回答による「（過去１年間）の医療機関で受診させた方がよいと思ったが，実際には受診…
View article: Effects of Partially Hydrolyzed Guar Gum Supplementation on the Fecal Microbiotas of Piglets
Effects of Partially Hydrolyzed Guar Gum Supplementation on the Fecal Microbiotas of Piglets Open
Probiotics and prebiotics have become viable alternatives of growth-promoting antimicrobials in animal production. Here, we tested partially hydrolyzed guar gum (PHGG) as a possible prebiotic for piglets in the commercial farm. Five hundre…
View article: Mothers’ nonstandard work schedules and adolescent obesity: a population-based cross-sectional study in the Tokyo metropolitan area
Mothers’ nonstandard work schedules and adolescent obesity: a population-based cross-sectional study in the Tokyo metropolitan area Open
Background Many wage earners in developed countries have irregular shift patterns and work evenings, nights, and weekends. Some studies have demonstrated that the nonstandard work schedules of parents have adverse effects on their children…